SOUKUP, Tomáš, I. ERŽEN, Isa JIRMANOVÁ, Gisela ZACHAŘOVÁ, Hana RAUCHOVÁ and Stanislav PAVELKA. Absence of thyroid hormones down regulates the expression of fast myosin heavy chain (MyHC) isoforms in regenerating soleus muscle isografted into fast extensor digitorum longus muscle. Physiological Research [IF=0.521(1998); SCI #cit.<2>]. 1999, vol. 48, 7,, p. S44-S46, 3 pp. ISSN 0862-8408.
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Basic information
Original name Absence of thyroid hormones down regulates the expression of fast myosin heavy chain (MyHC) isoforms in regenerating soleus muscle isografted into fast extensor digitorum longus muscle
Authors SOUKUP, Tomáš (203 Czech Republic), I. ERŽEN (705 Slovenia), Isa JIRMANOVÁ (203 Czech Republic), Gisela ZACHAŘOVÁ (203 Czech Republic), Hana RAUCHOVÁ (203 Czech Republic) and Stanislav PAVELKA (203 Czech Republic, guarantor).
Edition Physiological Research [IF=0.521(1998); SCI #cit.<2>], 1999, 0862-8408.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 10600 1.6 Biological sciences
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 0.521
RIV identification code RIV/00216224:14310/99:00001208
Organization unit Faculty of Science
Keywords in English muscle; myosin; thyroid hormone
Tags muscle, myosin, thyroid hormone
Tags International impact, Reviewed
Changed by Changed by: doc. RNDr. Stanislav Pavelka, CSc., učo 313. Changed: 9/4/2010 19:08.
Abstract
Slow soleus (SOL) muscles of 21- to 28-day-old inbred rats of the Lewis strain were grafted into the fast extensor digitorum longus (EDL) muscles in young adult euthyroid, hyperthyroid or hypothyroid inbred rats of the same strain. One to 12 months after the operation, rats were killed and muscle histochemical profiles and expression of myosin heavy chain (MyHC) isoforms were determined. From our results, it can be concluded that normal level of thyroid hormones is necessary for the expression of fast MyHC isoforms in the regenerating SOL muscle reinnervated by the fast EDL nerve.
Links
GA304/97/0516, research and development projectName: Analýza vlivu myogenních a neurogenních faktorů na expresi specifického fenotypu intrafuzálních svalových vláken
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