PREISLER, J. a E. S. YEUNG. Laser Photodissociation of Insulin Ions Generated by Matrix-Assisted Laser Desorption. Analytical Chemistry. Washington, D.C., USA: American Chemical Society, 1997, roč. 69, č. 21, s. 4390-4398. ISSN 0003-2700. |
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@article{216651, author = {Preisler, J. and Yeung, E. S.}, article_location = {Washington, D.C., USA}, article_number = {21}, keywords = {laser; photodissociation; MALDI; matrix; desorption; insulin;}, language = {eng}, issn = {0003-2700}, journal = {Analytical Chemistry}, title = {Laser Photodissociation of Insulin Ions Generated by Matrix-Assisted Laser Desorption}, volume = {69}, year = {1997} }
TY - JOUR ID - 216651 AU - Preisler, J. - Yeung, E. S. PY - 1997 TI - Laser Photodissociation of Insulin Ions Generated by Matrix-Assisted Laser Desorption JF - Analytical Chemistry VL - 69 IS - 21 SP - 4390 EP - 4390 PB - American Chemical Society SN - 00032700 KW - laser KW - photodissociation KW - MALDI KW - matrix KW - desorption KW - insulin; N2 - A novel method for studying the ionization step of matrixassisted laser desorption/ionization (MALDI) is demonstrated. A 193-nm pulse from an ArF excimer laser is used to photodissociate a portion of a plume of insulin ions generated by MALDI. Laser photodissociation (LPD) creates a "hole", i.e., a negative spike in the insulin peak in the time-of-flight (TOF) mass spectrum. The position of the hole in the mass spectrum provides useful measurements of the characteristics (position, time, and velocity) of insulin ions shortly after their creation. Although the performance of the method can be further improved, the data obtained could be used to refine our current understanding of MALDI and to improve the resolution of MALDI-TOFMS. ER -
PREISLER, J. a E. S. YEUNG. Laser Photodissociation of Insulin Ions Generated by Matrix-Assisted Laser Desorption. \textit{Analytical Chemistry}. Washington, D.C., USA: American Chemical Society, 1997, roč.~69, č.~21, s.~4390-4398. ISSN~0003-2700.
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