Case Report: Repeated Stereotactic Radiotherapy of Recurrent
Ventricular Tachycardia: Reasons, Feasibility, and Safety

J 2022

Case Report: Repeated Stereotactic Radiotherapy of Recurrent Ventricular Tachycardia: Reasons, Feasibility, and Safety

HASKOVA, Jana, Petr PEICHL, Šramko MAREK, Jakub CVEK, Knybel LUKAS et. al.

Základní údaje

Originální název

Case Report: Repeated Stereotactic Radiotherapy of Recurrent Ventricular Tachycardia: Reasons, Feasibility, and Safety

Autoři

HASKOVA, Jana (203 Česká republika, garant), Petr PEICHL (203 Česká republika), Šramko MAREK (203 Česká republika), Jakub CVEK (203 Česká republika), Knybel LUKAS (203 Česká republika), Otakar JIRAVSKÝ (203 Česká republika), Radek NEUWIRTH (203 Česká republika, domácí) a Josef KAUTZNER (203 Česká republika)

Vydání

FRONTIERS IN CARDIOVASCULAR MEDICINE, LAUSANNE, FRONTIERS MEDIA SA, 2022, 2297-055X

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30201 Cardiac and Cardiovascular systems

Stát vydavatele

Švýcarsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 3.600

Kód RIV

RIV/00216224:14110/22:00126387

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.3389/fcvm.2022.845382

UT WoS

000787883100001

Klíčová slova anglicky

Recurrent Ventricular Tachycardia; Repeated Stereotactic Radiotherapy

Štítky

14110211, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 1. 2. 2023 13:41, Mgr. Tereza Miškechová

Anotace

V originále

Stereotactic body radiotherapy (SBRT) has been reported as an attractive option for cases of failed catheter ablation of ventricular tachycardia (VT) in structural heart disease. However, even this strategy can fail for various reasons. For the first time, this case series describes three re-do cases of SBRT which were indicated for three different reasons. The purpose in the first case was the inaccuracy of the determination of the treatment volume by indirect comparison of the electroanatomical map and CT scan. A newly developed strategy of co-registration of both images allowed precise targeting of the substrate. In this case, the second treatment volume overlapped by 60% with the first one. The second reason for the re-do of SBRT was an unusual character of the substrate-large cardiac fibroma associated with different morphologies of VT from two locations around the tumor. The planned treatment volumes did not overlap. The third reason for repeated SBRT was the large intramural substrate in the setting of advanced heart failure. The first treatment volume targeted arrhythmias originating in the basal inferoseptal region, while the second SBRT was focused on adjacent basal septum without significant overlapping. Our observations suggested that SBRT for VT could be safely repeated in case of later arrhythmia recurrences (i.e., after at least 6 weeks). No acute toxicity was observed and in two cases, no side effects were observed during 32 and 22 months, respectively. To avoid re-do SBRT due to inaccurate targeting, the precise and reproducible strategy of substrate identification and co-registration with CT image should be used.

Citovat

HASKOVA, Jana, Petr PEICHL, Šramko MAREK, Jakub CVEK, Knybel LUKAS, Otakar JIRAVSKÝ, Radek NEUWIRTH a Josef KAUTZNER. Case Report: Repeated Stereotactic Radiotherapy of Recurrent Ventricular Tachycardia: Reasons, Feasibility, and Safety. FRONTIERS IN CARDIOVASCULAR MEDICINE. LAUSANNE: FRONTIERS MEDIA SA, 2022, roč. 9, March 2022, s. 1-9. ISSN 2297-055X. Dostupné z: https://dx.doi.org/10.3389/fcvm.2022.845382.

@article{2200457,
   author = {Haskova, Jana and Peichl, Petr and Marek, Šramko and Cvek, Jakub and Lukas, Knybel and Jiravský, Otakar and Neuwirth, Radek and Kautzner, Josef},
   article_location = {LAUSANNE},
   article_number = {March 2022},
   doi = {http://dx.doi.org/10.3389/fcvm.2022.845382},
   keywords = {Recurrent Ventricular Tachycardia; Repeated Stereotactic Radiotherapy},
   language = {eng},
   issn = {2297-055X},
   journal = {FRONTIERS IN CARDIOVASCULAR MEDICINE},
   title = {Case Report: Repeated Stereotactic Radiotherapy of Recurrent Ventricular Tachycardia: Reasons, Feasibility, and Safety},
   url = {https://www.frontiersin.org/articles/10.3389/fcvm.2022.845382/full},
   volume = {9},
   year = {2022}
}

TY  - JOUR
ID  - 2200457
AU  - Haskova, Jana - Peichl, Petr - Marek, Šramko - Cvek, Jakub - Lukas, Knybel - Jiravský, Otakar - Neuwirth, Radek - Kautzner, Josef
PY  - 2022
TI  - Case Report: Repeated Stereotactic Radiotherapy of Recurrent Ventricular Tachycardia: Reasons, Feasibility, and Safety
JF  - FRONTIERS IN CARDIOVASCULAR MEDICINE
VL  - 9
IS  - March 2022
SP  - 1-9
EP  - 1-9
PB  - FRONTIERS MEDIA SA
SN  - 2297055X
KW  - Recurrent Ventricular Tachycardia
KW  - Repeated Stereotactic Radiotherapy
UR  - https://www.frontiersin.org/articles/10.3389/fcvm.2022.845382/full
N2  - Stereotactic body radiotherapy (SBRT) has been reported as an attractive option for cases of failed catheter ablation of ventricular tachycardia (VT) in structural heart disease. However, even this strategy can fail for various reasons. For the first time, this case series describes three re-do cases of SBRT which were indicated for three different reasons. The purpose in the first case was the inaccuracy of the determination of the treatment volume by indirect comparison of the electroanatomical map and CT scan. A newly developed strategy of co-registration of both images allowed precise targeting of the substrate. In this case, the second treatment volume overlapped by 60% with the first one. The second reason for the re-do of SBRT was an unusual character of the substrate-large cardiac fibroma associated with different morphologies of VT from two locations around the tumor. The planned treatment volumes did not overlap. The third reason for repeated SBRT was the large intramural substrate in the setting of advanced heart failure. The first treatment volume targeted arrhythmias originating in the basal inferoseptal region, while the second SBRT was focused on adjacent basal septum without significant overlapping. Our observations suggested that SBRT for VT could be safely repeated in case of later arrhythmia recurrences (i.e., after at least 6 weeks). No acute toxicity was observed and in two cases, no side effects were observed during 32 and 22 months, respectively. To avoid re-do SBRT due to inaccurate targeting, the precise and reproducible strategy of substrate identification and co-registration with CT image should be used.
ER  -

HASKOVA, Jana, Petr PEICHL, Šramko MAREK, Jakub CVEK, Knybel LUKAS, Otakar JIRAVSKÝ, Radek NEUWIRTH a Josef KAUTZNER. Case Report: Repeated Stereotactic Radiotherapy of Recurrent Ventricular Tachycardia: Reasons, Feasibility, and Safety. \textit{FRONTIERS IN CARDIOVASCULAR MEDICINE}. LAUSANNE: FRONTIERS MEDIA SA, 2022, roč.~9, March 2022, s.~1-9. ISSN~2297-055X. Dostupné z: https://dx.doi.org/10.3389/fcvm.2022.845382.

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