Detailed Information on Publication Record
2022
NOVEL 1,3,5-TRIAZINYL AMINOBENZENESULFONAMIDES AS POTENT ANTI-VRE AGENTS
HAVRÁNKOVÁ, Eva, Josef JAMPÍLEK, Jozef CSÖLLEI, Vladimír GARAJ, Claudiu T. SUPURAN et. al.Basic information
Original name
NOVEL 1,3,5-TRIAZINYL AMINOBENZENESULFONAMIDES AS POTENT ANTI-VRE AGENTS
Authors
HAVRÁNKOVÁ, Eva (203 Czech Republic, guarantor, belonging to the institution), Josef JAMPÍLEK (703 Slovakia), Jozef CSÖLLEI (203 Czech Republic), Vladimír GARAJ (703 Slovakia) and Claudiu T. SUPURAN (380 Italy)
Edition
SAL 2022, 2022
Other information
Language
English
Type of outcome
Prezentace na konferencích
Field of Study
30107 Medicinal chemistry
Country of publisher
Czech Republic
Confidentiality degree
není předmětem státního či obchodního tajemství
References:
RIV identification code
RIV/00216224:14160/22:00126653
Organization unit
Faculty of Pharmacy
Keywords in English
carbonic anhydrases; vancomycin-resistant enterococci; anti-VRE agents; triazinyl-benzenesulfonamides
Změněno: 13/9/2022 14:19, RNDr. Eva Havránková, Ph.D.
Abstract
V originále
Carbonic anhydrases are metalloenzymes catalysing the reversible hydration of CO2, thereby affect the pH and affecting related physiological processes in various organisms. In pathogenic bacteria, CAs play an important role in survival and growth. Inhibition of bacterial CAs leads to growth retardation, growth defects and makes bacteria vulnerable to host defense mechanisms. Bacterial CAs are therefore a very promising target in the search for new antibiotics.
Links
| MUNI/A/1202/2020, interní kód MU |
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