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@proceedings{2220962,
author = {Rohan, Tomáš and Matkulčík, Peter and Uher, Michal and Čechová, Barbora and Straka, Matej and Válek, Vlastimil and Klail, Tomáš and Rosinová, Dominika and Andrašina, Tomáš},
booktitle = {CIRSE 2022},
doi = {http://dx.doi.org/10.1007/s00270-022-03246-4},
keywords = {biliary cancer; percutaneous transhepatic drainage; risk factors; survival},
language = {eng},
title = {Prognostic factors for survival in patients with unresectable cancer of biliary origin treated with percutaneous transhepatic drainage},
url = {https://programme.cirse2022.cirse.org/cirse2022poster/crs/prognostic-factors-for-survival-in-patients-with-unresectable-cancer-of-biliary-origin-treated-with-percutaneous-transhepatic-drainage},
year = {2022}
}
TY - CONF
ID - 2220962
AU - Rohan, Tomáš - Matkulčík, Peter - Uher, Michal - Čechová, Barbora - Straka, Matej - Válek, Vlastimil - Klail, Tomáš - Rosinová, Dominika - Andrašina, Tomáš
PY - 2022
TI - Prognostic factors for survival in patients with unresectable cancer of biliary origin treated with percutaneous transhepatic drainage
KW - biliary cancer
KW - percutaneous transhepatic drainage
KW - risk factors
KW - survival
UR - https://programme.cirse2022.cirse.org/cirse2022poster/crs/prognostic-factors-for-survival-in-patients-with-unresectable-cancer-of-biliary-origin-treated-with-percutaneous-transhepatic-drainage
N2 - Purpose: To identify factors affecting survival in patients with unresectable cancer of biliary origin treated with percutaneous transhepatic drainage (PTD). Materials and Methods: This single-centre retrospective study included 233 consecutive patients undergoing PTD for cancer of biliary origin at a tertiary referral hospital from 1/2005 to 12/2019. Cox regression model was used to assess variables related to overall survival after initial PTD. The variables included demographic (age, sex), imaging (mass forming vs. infiltrative, size of mass forming tumor, localisation, Bismuth-Corlette classification in hilar tumors, presence of metastasis), laboratory (bilirubin, liver enzymes and inflammatory markers before and 3-7 days after the procedure, and hemoglobin, thrombocytes, urea and creatinine before the procedure), and treatment parameters of PTD (number of percutaneous drains, presence and number of implanted metal stents, and performance of endobiliary radiofrequency ablation). Results: In multivariate analysis, age (HR 1.23 per 10 years, p=0.005), location (gallbladder cancer HR 2.82 and p<0.001 compared to hilar cancer; common bile duct cancer HR 0.64 and p=0.049; papilla Vateri HR 0.31 and p=0.002), size of the mass (HR 1.07 per cm, p=0.005), level of bilirubin (≥250 umol/L with HR 1.57 and p=0.009) and hemoglobin (≤110 g/L with HR 1.93 and p=0.001) were shown to be significant factors affecting survival in patients with cancer of biliary origin since first PTD. Conslusion: Age, tumour location, mass size, bilirubin and hemoglobin levels before the first PTD have been shown to be significant prognostic factors for survival in patients with cancer of biliary origin treated with PTD.
ER -
ROHAN, Tomáš, Peter MATKULČÍK, Michal UHER, Barbora ČECHOVÁ, Matej STRAKA, Vlastimil VÁLEK, Tomáš KLAIL, Dominika ROSINOVÁ a Tomáš ANDRAŠINA. Prognostic factors for survival in patients with unresectable cancer of biliary origin treated with percutaneous transhepatic drainage. In \textit{CIRSE 2022}. 2022. Dostupné z: https://dx.doi.org/10.1007/s00270-022-03246-4.
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