Diagnostic Test Accuracy of Existing Practices Identifying Type
2 Pre Diabetes in Children A Systematic Review of Diagnostic
Test Evidence

a 2022

Diagnostic Test Accuracy of Existing Practices Identifying Type 2 Pre Diabetes in Children A Systematic Review of Diagnostic Test Evidence

TUČKOVÁ, Dagmar, Abanoub RIAD, Simona SLEZÁKOVÁ a Miloslav KLUGAR

Základní údaje

Originální název

Diagnostic Test Accuracy of Existing Practices Identifying Type 2 Pre Diabetes in Children A Systematic Review of Diagnostic Test Evidence

Autoři

TUČKOVÁ, Dagmar, Abanoub RIAD, Simona SLEZÁKOVÁ a Miloslav KLUGAR

Vydání

GIN 2022, Toronto, 2022

Další údaje

Jazyk

angličtina

Typ výsledku

Konferenční abstrakt

Obor

30202 Endocrinology and metabolism

Stát vydavatele

Kanada

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Organizační jednotka

Lékařská fakulta

Klíčová slova anglicky

diabetes; diagnostic test accuracy;

Změněno: 10. 10. 2022 09:39, Mgr. Bc. Alena Langaufová, Ph.D.

Anotace

V originále

Background 422 million people worldwide have diabetes. In 2019, diabetes was direct of 1.5 million deaths. Between 2000 and 2016, there was a 5% increase in premature mortality from diabetes. The need for a practical, accurate diagnostic test for pediatric patients is great due to the epidemic of childhood obesity in developed countries. Objective Systematic review objective was to identify all alternative tests currently in use for the diagnosis of type 2 pre-diabetes in children and establish their accuracy relative to gold standard. Methods We followed JBI methodology for systematic review of diagnostic test accuracy (DTA SR). Threephases search strategy was used. Two independent reviewers screened, critically appraised, extracted and synthesized data. We performed meta-analyses for sensitivity and specificity of diagnostic tests. SROC (Summary receiver operating curve) plot of tests was utilized as well. Results Total number of four studies was possible to be pooled in the meta-analyses. SR DTA provided evidence of the accuracy: FPG ≥7.0 mmol/L versus OGTT in two studies in two different populations. Three diagnostic tests are recommended for a practice (FPG ≥7.0 mmol/l versus OGTT, HbA1c 6.5 % versus OGTT, and TG_HDL 1.71 mmol/L versus HOMA-IR). Discussion Based on results, it can be further discussed how important predictor is ethnicity and ontogenetic development in determining of cut off points.

Citovat

TUČKOVÁ, Dagmar, Abanoub RIAD, Simona SLEZÁKOVÁ a Miloslav KLUGAR. Diagnostic Test Accuracy of Existing Practices Identifying Type 2 Pre Diabetes in Children A Systematic Review of Diagnostic Test Evidence. In GIN 2022, Toronto. 2022.

@proceedings{2223804,
   author = {Tučková, Dagmar and Riad, Abanoub and Slezáková, Simona and Klugar, Miloslav},
   booktitle = {GIN 2022, Toronto},
   keywords = {diabetes; diagnostic test accuracy;},
   language = {eng},
   title = {Diagnostic Test Accuracy of Existing Practices Identifying Type 2 Pre Diabetes in Children A Systematic Review of Diagnostic Test Evidence},
   url = {http://icsevents.eventsair.com/gin2022/},
   year = {2022}
}

TY  - CONF
ID  - 2223804
AU  - Tučková, Dagmar - Riad, Abanoub - Slezáková, Simona - Klugar, Miloslav
PY  - 2022
TI  - Diagnostic Test Accuracy of Existing Practices Identifying Type 2 Pre Diabetes in Children A Systematic Review of Diagnostic Test Evidence
KW  - diabetes
KW  - diagnostic test accuracy;
UR  - http://icsevents.eventsair.com/gin2022/
N2  - Background 422 million people worldwide have diabetes. In 2019, diabetes was direct of 1.5 million deaths. Between 2000 and 2016, there was a 5% increase in premature mortality from diabetes. The need for a practical, accurate diagnostic test for pediatric patients is great due to the epidemic of childhood obesity in developed countries. Objective Systematic review objective was to identify all alternative tests currently in use for the diagnosis of type 2 pre-diabetes in children and establish their accuracy relative to gold standard. Methods We followed JBI methodology for systematic review of diagnostic test accuracy (DTA SR). Threephases search strategy was used. Two independent reviewers screened, critically appraised, extracted and synthesized data. We performed meta-analyses for sensitivity and specificity of diagnostic tests. SROC (Summary receiver operating curve) plot of tests was utilized as well. Results Total number of four studies was possible to be pooled in the meta-analyses. SR DTA provided evidence of the accuracy: FPG ≥7.0 mmol/L versus OGTT in two studies in two different populations. Three diagnostic tests are recommended for a practice (FPG ≥7.0 mmol/l versus OGTT, HbA1c 6.5 % versus OGTT, and TG_HDL 1.71 mmol/L versus HOMA-IR). Discussion Based on results, it can be further discussed how important predictor is ethnicity and ontogenetic development in determining of cut off points.
ER  -

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