2019
Nanoparticles as tags for protein tissue analysis using laser ablation inductively coupled plasma and mass spectrometry
KUCHYNKA, Michaela, Michal MASAŘÍK, Marcela VLČNOVSKÁ, Viktor KANICKÝ, Tomáš VACULOVIČ et. al.Základní údaje
Originální název
Nanoparticles as tags for protein tissue analysis using laser ablation inductively coupled plasma and mass spectrometry
Název anglicky
Nanoparticles as tags for protein tissue analysis using laser ablation inductively coupled plasma and mass spectrometry
Autoři
Vydání
2019
Další údaje
Typ výsledku
Prezentace na konferencích
Utajení
není předmětem státního či obchodního tajemství
Klíčová slova anglicky
Nanoparticles; Bioimaging; LA, ICP, MS; Immunochemistry
Příznaky
Mezinárodní význam
Změněno: 21. 10. 2022 13:20, Mgr. Michaela Kuchynka, Ph.D.
Anotace
V originále
Laser ablation with inductively coupled plasma is still more used in life science as biology and biomedicine and the utilization of metals and proteins determination simultaneously is also growing up. We have developed a new strategy of antibody labeling by nanoparticles which are composed of thousands of atoms and thus increase the sensitivity enormously and decrease the limit of detection (tens of picograms). The ability of simultaneous imaging proteins such as p53 and elements and their distribution in biological tissue (especially tumour) is presented in this work.
Návaznosti
GA17-12774S, projekt VaV |
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LQ1601, projekt VaV |
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