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@article{2229948,
author = {Motil, Igor and Macík, Daniel and Šrámková, Kateřina and Jarkovský, Jiří and Šrámková, Taťána},
article_location = {BASEL},
article_number = {10},
doi = {http://dx.doi.org/10.1159/000525973},
keywords = {Shockwave therapy; Penile rehabilitation; Erectile dysfunction; Radical prostatectomy},
language = {eng},
issn = {0042-1138},
journal = {UROLOGIA INTERNATIONALIS},
title = {Linear Low-Intensity Extracorporeal Shockwave Therapy as a Method for Penile Rehabilitation in Erectile Dysfunction Patients after Radical Prostatectomy: A Randomized, Single-Blinded, Sham-Controlled Clinical Trial},
url = {https://www.karger.com/Article/FullText/525973},
volume = {106},
year = {2022}
}
TY - JOUR
ID - 2229948
AU - Motil, Igor - Macík, Daniel - Šrámková, Kateřina - Jarkovský, Jiří - Šrámková, Taťána
PY - 2022
TI - Linear Low-Intensity Extracorporeal Shockwave Therapy as a Method for Penile Rehabilitation in Erectile Dysfunction Patients after Radical Prostatectomy: A Randomized, Single-Blinded, Sham-Controlled Clinical Trial
JF - UROLOGIA INTERNATIONALIS
VL - 106
IS - 10
SP - 1050-1055
EP - 1050-1055
PB - KARGER
SN - 00421138
KW - Shockwave therapy
KW - Penile rehabilitation
KW - Erectile dysfunction
KW - Radical prostatectomy
UR - https://www.karger.com/Article/FullText/525973
N2 - Introduction: The objective of this study was to investigate the effect and feasibility of linear low-intensity extracorporeal shockwave therapy (LI-LiESWT) as a penile rehabilitation method for erectile dysfunction (ED) after bilateral nerve-sparing (NS) radical prostatectomy (RP). Methods: Patients who had undergone bilateral NS RP (either radical retropubic prostatectomy or robot-assisted laparoscopic RP), 3 or more months prior to the study, and who had no ED preoperatively and were suffering from mild to severe postoperative ED were included in the study. Four treatments were given over a 4-week period, using the PiezoWave2 device with a linear shockwave applicator and the linear shockwave tissue coverage (LSTC-ED®) technique. If the improvement in erectile function was still considered insufficient (less than an IIEF-5 score of 22–25) at 2 months after the start of LI-LiESWT, penile rehabilitation was supplemented by pharmacological penile rehabilitation. The final effect of treatment was evaluated after 12 months. The main outcome measure was changes in the five-item International Index of Erectile Function (IIEF-5) score. Results: Between September 2019 and September 2020, a total of 40 patients were included in the study and randomly divided into 2 groups: treatment group and sham group. Eight patients were excluded from the study and were not evaluated due to other conditions which required additional treatment (COVID-19 disease, postoperative incontinence, urethral stricture, and ischemic stroke). Thirty-two patients were included in the final analysis: 16 in the control group and 16 in the intervention group. At 6 months from the end of treatment, patients in both the treatment and the sham group achieved physiological IIEF-5 values, and the beneficial effect persisted for 12 months after the end of treatment. Conclusions: LI-LiESWT using the LSTC-ED® technique is a suitable and safe method for penile rehabilitation in patients with ED after bilateral NS RP, not only because of the vasculogenic effect of LI-LiESWT but also because of its neuroprotective and/or regenerative effects.
ER -
MOTIL, Igor, Daniel MACÍK, Kateřina ŠRÁMKOVÁ, Jiří JARKOVSKÝ and Taťána ŠRÁMKOVÁ. Linear Low-Intensity Extracorporeal Shockwave Therapy as a Method for Penile Rehabilitation in Erectile Dysfunction Patients after Radical Prostatectomy: A Randomized, Single-Blinded, Sham-Controlled Clinical Trial. \textit{UROLOGIA INTERNATIONALIS}. BASEL: KARGER, 2022, vol.~106, No~10, p.~1050-1055. ISSN~0042-1138. Available from: https://dx.doi.org/10.1159/000525973.
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