Is non-invasive brain stimulation effective for cognitive
enhancement in Alzheimer?s disease? An updated meta-analysis

J 2022

Is non-invasive brain stimulation effective for cognitive enhancement in Alzheimer?s disease? An updated meta-analysis

ŠIMKO, Patrik, Julia Anna KENT a Irena REKTOROVÁ

Základní údaje

Originální název

Is non-invasive brain stimulation effective for cognitive enhancement in Alzheimer?s disease? An updated meta-analysis

Autoři

ŠIMKO, Patrik (703 Slovensko, domácí), Julia Anna KENT (203 Česká republika, domácí) a Irena REKTOROVÁ (203 Česká republika, garant, domácí)

Vydání

Clinical Neurophysiology, Clare, Elsevier Ireland, 2022, 1388-2457

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30103 Neurosciences

Stát vydavatele

Irsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 4.700

Kód RIV

RIV/00216224:14740/22:00129715

Organizační jednotka

Středoevropský technologický institut

DOI

http://dx.doi.org/10.1016/j.clinph.2022.09.010

UT WoS

000886064800004

Klíčová slova anglicky

Brain stimulation; Noninvasive; tDCS; rTMS; Dementia; Alzheimer?s disease; Mild cognitive impairment; MCI

Štítky

14110127, 14110132, podil, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 13. 12. 2022 14:12, Mgr. Pavla Foltynová, Ph.D.

Anotace

V originále

Objective: Alzheimer's disease dementia (AD) and its preclinical stage, mild cognitive impairment (MCI), are critical issues confronting the aging society. Non-invasive brain stimulation (NIBS) techniques have the potential to be effective tools for enhancing cognitive functioning. The main objective of our meta -analysis was to quantify and update the status of the efficacy of repetitive Transcranial Magnetic Stimulation (rTMS) and Transcranial Direct Current Stimulation (tDCS) when applied in AD and MCI.Methods: The systematic literature search was conducted in PubMed and Web of Science according to PRISMA statement.Results: Pooled effect sizes (Hedges' g) from 32 studies were analyzed using random effect models. We found both, rTMS and tDCS to have significant immediate cognition-enhancing effect in AD with rTMS inducing also beneficial long-term effects. We found no evidence for synergistic effect of cognitive train-ing with NIBS.Conclusions: In AD a clinical recommendation can be made for NEURO-ADTM system and for high -frequency rTMS over the left dorsolateral prefrontal cortex (DLPFC) as probably effective protocols (B -level of evidence) and for anodal tDCS over the left DLPFC as a possibly effective.Significance: According to scientific literature, NIBS may be an effective method for improving cognition in AD and possibly in MCI.(c) 2022 International Federation of Clinical Neurophysiology. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

Návaznosti

NV18-04-00256, projekt VaV

Název: Efekt transkraniální stimulace tDCS na zrakovou pozornost u pacientů s mírnou kognitivní poruchou - studie kombinující MRI a neinvazivní mozkovou stimulaci

Investor: Ministerstvo zdravotnictví ČR, The effect of transcranial direct current stimulation on visual attention in mild cognitive impairment – a combined fMRI and non-invasive brain stimulation study

Citovat

ŠIMKO, Patrik, Julia Anna KENT a Irena REKTOROVÁ. Is non-invasive brain stimulation effective for cognitive enhancement in Alzheimer?s disease? An updated meta-analysis. Clinical Neurophysiology. Clare: Elsevier Ireland, 2022, roč. 144, DEC, s. 23-40. ISSN 1388-2457. Dostupné z: https://dx.doi.org/10.1016/j.clinph.2022.09.010.

@article{2237540,
   author = {Šimko, Patrik and Kent, Julia Anna and Rektorová, Irena},
   article_location = {Clare},
   article_number = {DEC},
   doi = {http://dx.doi.org/10.1016/j.clinph.2022.09.010},
   keywords = {Brain stimulation; Noninvasive; tDCS; rTMS; Dementia; Alzheimer?s disease; Mild cognitive impairment; MCI},
   language = {eng},
   issn = {1388-2457},
   journal = {Clinical Neurophysiology},
   title = {Is non-invasive brain stimulation effective for cognitive enhancement in Alzheimer?s disease? An updated meta-analysis},
   url = {https://www.sciencedirect.com/science/article/pii/S1388245722008975?via%3Dihub},
   volume = {144},
   year = {2022}
}

TY  - JOUR
ID  - 2237540
AU  - Šimko, Patrik - Kent, Julia Anna - Rektorová, Irena
PY  - 2022
TI  - Is non-invasive brain stimulation effective for cognitive enhancement in Alzheimer?s disease? An updated meta-analysis
JF  - Clinical Neurophysiology
VL  - 144
IS  - DEC
SP  - 23-40
EP  - 23-40
PB  - Elsevier Ireland
SN  - 13882457
KW  - Brain stimulation
KW  - Noninvasive
KW  - tDCS
KW  - rTMS
KW  - Dementia
KW  - Alzheimer?s disease
KW  - Mild cognitive impairment
KW  - MCI
UR  - https://www.sciencedirect.com/science/article/pii/S1388245722008975?via%3Dihub
N2  - Objective: Alzheimer's disease dementia (AD) and its preclinical stage, mild cognitive impairment (MCI), are critical issues confronting the aging society. Non-invasive brain stimulation (NIBS) techniques have the potential to be effective tools for enhancing cognitive functioning. The main objective of our meta -analysis was to quantify and update the status of the efficacy of repetitive Transcranial Magnetic Stimulation (rTMS) and Transcranial Direct Current Stimulation (tDCS) when applied in AD and MCI.Methods: The systematic literature search was conducted in PubMed and Web of Science according to PRISMA statement.Results: Pooled effect sizes (Hedges' g) from 32 studies were analyzed using random effect models. We found both, rTMS and tDCS to have significant immediate cognition-enhancing effect in AD with rTMS inducing also beneficial long-term effects. We found no evidence for synergistic effect of cognitive train-ing with NIBS.Conclusions: In AD a clinical recommendation can be made for NEURO-ADTM system and for high -frequency rTMS over the left dorsolateral prefrontal cortex (DLPFC) as probably effective protocols (B -level of evidence) and for anodal tDCS over the left DLPFC as a possibly effective.Significance: According to scientific literature, NIBS may be an effective method for improving cognition in AD and possibly in MCI.(c) 2022 International Federation of Clinical Neurophysiology. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
ER  -

ŠIMKO, Patrik, Julia Anna KENT a Irena REKTOROVÁ. Is non-invasive brain stimulation effective for cognitive enhancement in Alzheimer?s disease? An updated meta-analysis. \textit{Clinical Neurophysiology}. Clare: Elsevier Ireland, 2022, roč.~144, DEC, s.~23-40. ISSN~1388-2457. Dostupné z: https://dx.doi.org/10.1016/j.clinph.2022.09.010.

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