| SOLÁR, Peter, Zdeněk MACKERLE, Michal HENDRYCH, Petr POSPÍŠIL, Radek LAKOMÝ, Hana VALEKOVÁ, Markéta HERMANOVÁ and Radim JANČÁLEK. Prolonged survival in patients with local chronic infection after high-grade glioma treatment: two case reports. FRONTIERS IN ONCOLOGY. LAUSANNE: FRONTIERS MEDIA SA, 2022, vol. 12, December 2022, p. 1-7. ISSN 2234-943X. Available from: https://dx.doi.org/10.3389/fonc.2022.1073036. |
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@article{2237877,
author = {Solár, Peter and Mackerle, Zdeněk and Hendrych, Michal and Pospíšil, Petr and Lakomý, Radek and Valeková, Hana and Hermanová, Markéta and Jančálek, Radim},
article_location = {LAUSANNE},
article_number = {December 2022},
doi = {http://dx.doi.org/10.3389/fonc.2022.1073036},
keywords = {high-grade glioma; glioblastoma; anaplastic astrocytoma; wound infection; prolonged survival},
language = {eng},
issn = {2234-943X},
journal = {FRONTIERS IN ONCOLOGY},
title = {Prolonged survival in patients with local chronic infection after high-grade glioma treatment: two case reports},
url = {https://www.frontiersin.org/articles/10.3389/fonc.2022.1073036/full},
volume = {12},
year = {2022}
}
TY - JOUR
ID - 2237877
AU - Solár, Peter - Mackerle, Zdeněk - Hendrych, Michal - Pospíšil, Petr - Lakomý, Radek - Valeková, Hana - Hermanová, Markéta - Jančálek, Radim
PY - 2022
TI - Prolonged survival in patients with local chronic infection after high-grade glioma treatment: two case reports
JF - FRONTIERS IN ONCOLOGY
VL - 12
IS - December 2022
SP - 1-7
EP - 1-7
PB - FRONTIERS MEDIA SA
SN - 2234943X
KW - high-grade glioma
KW - glioblastoma
KW - anaplastic astrocytoma
KW - wound infection
KW - prolonged survival
UR - https://www.frontiersin.org/articles/10.3389/fonc.2022.1073036/full
N2 - High-grade gliomas are primary brain tumors with poor prognosis, despite surgical treatment followed by radiotherapy and concomitant chemotherapy. We present two cases of long-term survival in patients treated for high-grade glioma and concomitant prolonged bacterial wound infection. The first patient treated for glioblastoma IDH-wildtype had been without disease progression for 61 months from the first resected recurrence. Despite incomplete chemotherapy-induced myelosuppression in the second patient with anaplastic astrocytoma IDH-mutant, she died without disease relapse after 14 years from the diagnosis due to other comorbidities. We assume that the documented prolonged survival could be related to the bacterial infection.
ER -
SOLÁR, Peter, Zdeněk MACKERLE, Michal HENDRYCH, Petr POSPÍŠIL, Radek LAKOMÝ, Hana VALEKOVÁ, Markéta HERMANOVÁ and Radim JANČÁLEK. Prolonged survival in patients with local chronic infection after high-grade glioma treatment: two case reports. \textit{FRONTIERS IN ONCOLOGY}. LAUSANNE: FRONTIERS MEDIA SA, 2022, vol.~12, December 2022, p.~1-7. ISSN~2234-943X. Available from: https://dx.doi.org/10.3389/fonc.2022.1073036.
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