Prolonged survival in patients with local chronic infection
after high-grade glioma treatment: two case reports

J 2022

Prolonged survival in patients with local chronic infection after high-grade glioma treatment: two case reports

SOLÁR, Peter, Zdeněk MACKERLE, Michal HENDRYCH, Petr POSPÍŠIL, Radek LAKOMÝ et. al.

Základní údaje

Originální název

Prolonged survival in patients with local chronic infection after high-grade glioma treatment: two case reports

Autoři

SOLÁR, Peter (703 Slovensko, domácí), Zdeněk MACKERLE (203 Česká republika, domácí), Michal HENDRYCH (203 Česká republika, domácí), Petr POSPÍŠIL (203 Česká republika, domácí), Radek LAKOMÝ (203 Česká republika, domácí), Hana VALEKOVÁ (703 Slovensko, domácí), Markéta HERMANOVÁ (203 Česká republika, domácí) a Radim JANČÁLEK (203 Česká republika, garant, domácí)

Vydání

FRONTIERS IN ONCOLOGY, LAUSANNE, FRONTIERS MEDIA SA, 2022, 2234-943X

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30204 Oncology

Stát vydavatele

Švýcarsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 4.700

Kód RIV

RIV/00216224:14110/22:00127373

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.3389/fonc.2022.1073036

UT WoS

000904981000001

Klíčová slova anglicky

high-grade glioma; glioblastoma; anaplastic astrocytoma; wound infection; prolonged survival

Štítky

14110112, 14110131, 14110811, 14110812, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 31. 1. 2023 15:26, Mgr. Tereza Miškechová

Anotace

V originále

High-grade gliomas are primary brain tumors with poor prognosis, despite surgical treatment followed by radiotherapy and concomitant chemotherapy. We present two cases of long-term survival in patients treated for high-grade glioma and concomitant prolonged bacterial wound infection. The first patient treated for glioblastoma IDH-wildtype had been without disease progression for 61 months from the first resected recurrence. Despite incomplete chemotherapy-induced myelosuppression in the second patient with anaplastic astrocytoma IDH-mutant, she died without disease relapse after 14 years from the diagnosis due to other comorbidities. We assume that the documented prolonged survival could be related to the bacterial infection.

Návaznosti

MUNI/A/1408/2021, interní kód MU

Název: Organotypické kultury glioblastomu – personalizované testování protinádorové léčby

Investor: Masarykova univerzita, Organotypické kultury glioblastomu – personalizované testování protinádorové léčby

Citovat

SOLÁR, Peter, Zdeněk MACKERLE, Michal HENDRYCH, Petr POSPÍŠIL, Radek LAKOMÝ, Hana VALEKOVÁ, Markéta HERMANOVÁ a Radim JANČÁLEK. Prolonged survival in patients with local chronic infection after high-grade glioma treatment: two case reports. FRONTIERS IN ONCOLOGY. LAUSANNE: FRONTIERS MEDIA SA, 2022, roč. 12, December 2022, s. 1-7. ISSN 2234-943X. Dostupné z: https://dx.doi.org/10.3389/fonc.2022.1073036.

@article{2237877,
   author = {Solár, Peter and Mackerle, Zdeněk and Hendrych, Michal and Pospíšil, Petr and Lakomý, Radek and Valeková, Hana and Hermanová, Markéta and Jančálek, Radim},
   article_location = {LAUSANNE},
   article_number = {December 2022},
   doi = {http://dx.doi.org/10.3389/fonc.2022.1073036},
   keywords = {high-grade glioma; glioblastoma; anaplastic astrocytoma; wound infection; prolonged survival},
   language = {eng},
   issn = {2234-943X},
   journal = {FRONTIERS IN ONCOLOGY},
   title = {Prolonged survival in patients with local chronic infection after high-grade glioma treatment: two case reports},
   url = {https://www.frontiersin.org/articles/10.3389/fonc.2022.1073036/full},
   volume = {12},
   year = {2022}
}

TY  - JOUR
ID  - 2237877
AU  - Solár, Peter - Mackerle, Zdeněk - Hendrych, Michal - Pospíšil, Petr - Lakomý, Radek - Valeková, Hana - Hermanová, Markéta - Jančálek, Radim
PY  - 2022
TI  - Prolonged survival in patients with local chronic infection after high-grade glioma treatment: two case reports
JF  - FRONTIERS IN ONCOLOGY
VL  - 12
IS  - December 2022
SP  - 1-7
EP  - 1-7
PB  - FRONTIERS MEDIA SA
SN  - 2234943X
KW  - high-grade glioma
KW  - glioblastoma
KW  - anaplastic astrocytoma
KW  - wound infection
KW  - prolonged survival
UR  - https://www.frontiersin.org/articles/10.3389/fonc.2022.1073036/full
N2  - High-grade gliomas are primary brain tumors with poor prognosis, despite surgical treatment followed by radiotherapy and concomitant chemotherapy. We present two cases of long-term survival in patients treated for high-grade glioma and concomitant prolonged bacterial wound infection. The first patient treated for glioblastoma IDH-wildtype had been without disease progression for 61 months from the first resected recurrence. Despite incomplete chemotherapy-induced myelosuppression in the second patient with anaplastic astrocytoma IDH-mutant, she died without disease relapse after 14 years from the diagnosis due to other comorbidities. We assume that the documented prolonged survival could be related to the bacterial infection.
ER  -

SOLÁR, Peter, Zdeněk MACKERLE, Michal HENDRYCH, Petr POSPÍŠIL, Radek LAKOMÝ, Hana VALEKOVÁ, Markéta HERMANOVÁ a Radim JANČÁLEK. Prolonged survival in patients with local chronic infection after high-grade glioma treatment: two case reports. \textit{FRONTIERS IN ONCOLOGY}. LAUSANNE: FRONTIERS MEDIA SA, 2022, roč.~12, December 2022, s.~1-7. ISSN~2234-943X. Dostupné z: https://dx.doi.org/10.3389/fonc.2022.1073036.

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