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@article{2239697, author = {ARMOCIDA, Benedetta and MONASTA, Lorenzo and SAWYER, Susan and BUSTREO, Flavia and SEGAFREDO, Giulia and CASTELPIETRA, Giulio and RONFANI, Luca and PASOVIC, Maja and HAY, Simon and PEREL, Pablo and BERAN, David and Klugar, Miloslav and Klugarová, Jitka and Riad, Abanoub and Hussain, Mohammad Salman}, article_number = {6}, doi = {http://dx.doi.org/10.1016/S2352-4642(22)00073-6}, keywords = {non-communicable diseases; mental disorders;}, issn = {2352-4642}, title = {Burden of non-communicable diseases among adolescents aged 10–24 years in the EU, 1990–2019: a systematic analysis of the Global Burden of Diseases Study 2019}, volume = {6}, year = {2022} }
TY - JOUR ID - 2239697 AU - ARMOCIDA, Benedetta - MONASTA, Lorenzo - SAWYER, Susan - BUSTREO, Flavia - SEGAFREDO, Giulia - CASTELPIETRA, Giulio - RONFANI, Luca - PASOVIC, Maja - HAY, Simon - PEREL, Pablo - BERAN, David - Klugar, Miloslav - Klugarová, Jitka - Riad, Abanoub - Hussain, Mohammad Salman PY - 2022 TI - Burden of non-communicable diseases among adolescents aged 10–24 years in the EU, 1990–2019: a systematic analysis of the Global Burden of Diseases Study 2019 VL - 6 IS - 6 SP - 367-383 EP - 367-383 SN - 23524642 KW - non-communicable diseases KW - mental disorders; N2 - Background Disability and mortality burden of non-communicable diseases (NCDs) have risen worldwide; however, the NCD burden among adolescents remains poorly described in the EU. Methods Estimates were retrieved from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019. Causes of NCDs were analysed at three different levels of the GBD 2019 hierarchy, for which mortality, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs) were extracted. Estimates, with the 95% uncertainty intervals (UI), were retrieved for EU Member States from 1990 to 2019, three age subgroups (10–14 years, 15–19 years, and 20–24 years), and by sex. Spearman’s correlation was conducted between DALY rates for NCDs and the Socio-demographic Index (SDI) of each EU Member State. Findings In 2019, NCDs accounted for 86·4% (95% uncertainty interval 83·5–88·8) of all YLDs and 38·8% (37·4–39·8) of total deaths in adolescents aged 10–24 years. For NCDs in this age group, neoplasms were the leading causes of both mortality (4·01 [95% uncertainty interval 3·62–4·25] per 100000 population) and YLLs (281·78 [254·25–298·92] per 100000 population), whereas mental disorders were the leading cause for YLDs (2039·36 [1432·56–2773·47] per 100000 population) and DALYs (2040·59 [1433·96–2774·62] per 100000 population) in all EU Member States, and in all studied age groups. In 2019, among adolescents aged 10–24 years, males had a higher mortality rate per 100000 population due to NCDs than females (11·66 [11·04–12·28] vs 7·89 [7·53–8·23]), whereas females presented a higher DALY rate per 100000 population due to NCDs (8003·25 [5812·78–10701·59] vs 6083·91 [4576·63–7857·92]). From 1990 to 2019, mortality rate due to NCDs in adolescents aged 10–24 years substantially decreased (–40·41% [–43·00 to –37·61), and also the YLL rate considerably decreased (–40·56% [–43·16 to –37·74]), except for mental disorders (which increased by 32·18% [1·67 to 66·49]), whereas the YLD rate increased slightly (1·44% [0·09 to 2·79]). Positive correlations were observed between DALY rates and SDIs for substance use disorders (rs =0·58, p=0·0012) and skin and subcutaneous diseases (rs =0·45, p=0·017), whereas negative correlations were found between DALY rates and SDIs for cardiovascular diseases (rs =–0·46, p=0·015), neoplasms (rs =–0·57, p=0·0015), and sense organ diseases (rs =–0·61, p=0·0005). Interpretation NCD-related mortality has substantially declined among adolescents in the EU between 1990 and 2019, but the rising trend of YLL attributed to mental disorders and their YLD burden are concerning. Differences by sex, age group, and across EU Member States highlight the importance of preventive interventions and scaling up adolescent-responsive health-care systems, which should prioritise specific needs by sex, age, and location. ER -
ARMOCIDA, Benedetta, Lorenzo MONASTA, Susan SAWYER, Flavia BUSTREO, Giulia SEGAFREDO, Giulio CASTELPIETRA, Luca RONFANI, Maja PASOVIC, Simon HAY, Pablo PEREL a David BERAN. Burden of non-communicable diseases among adolescents aged 10–24 years in the EU, 1990–2019: a systematic analysis of the Global Burden of Diseases Study 2019. 2022, roč.~6, č.~6, s.~367-383. ISSN~2352-4642. Dostupné z: https://dx.doi.org/10.1016/S2352-4642(22)00073-6.
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