Meiotic exit in Arabidopsis is driven by P-body-mediated
inhibition of translation

J 2022

Meiotic exit in Arabidopsis is driven by P-body-mediated inhibition of translation

CAIRO CALZADA, Albert, Anna VARGOVÁ, Neha SHUKLA, Claudio CAPITAO, Pavlína MIKULKOVÁ et. al.

Základní údaje

Originální název

Meiotic exit in Arabidopsis is driven by P-body-mediated inhibition of translation

Autoři

CAIRO CALZADA, Albert (724 Španělsko, domácí), Anna VARGOVÁ (703 Slovensko, domácí), Neha SHUKLA (356 Indie, domácí), Claudio CAPITAO, Pavlína MIKULKOVÁ (203 Česká republika, domácí), Soňa VALUCHOVÁ (703 Slovensko, domácí), Jana PEČINKOVÁ (203 Česká republika, domácí), Petra BULANKOVA a Karel ŘÍHA (203 Česká republika, garant, domácí)

Vydání

Science, WASHINGTON, AMER ASSOC ADVANCEMENT SCIENCE, 2022, 0036-8075

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10608 Biochemistry and molecular biology

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 56.900

Kód RIV

RIV/00216224:14740/22:00127511

Organizační jednotka

Středoevropský technologický institut

DOI

http://dx.doi.org/10.1126/science.abo0904

UT WoS

000837874700039

Klíčová slova anglicky

MESSENGER-RNA DECAY; SMG7; PROGRAM; PROTEIN; MEIOSIS; REVEALS;BODIES

Štítky

CF CELLIM, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 8. 10. 2024 10:31, Ing. Martina Blahová

Anotace

V originále

Meiosis, at the transition between diploid and haploid life cycle phases, is accompanied by reprograming of cell division machinery and followed by a transition back to mitosis. We show that, in Arabidopsis, this transition is driven by inhibition of translation, achieved by a mechanism that involves processing bodies (P-bodies). During the second meiotic division, the meiosis-specific protein THREE-DIVISION MUTANT 1 (TDM1) is incorporated into P-bodies through interaction with SUPPRESSOR WITH MORPHOGENETIC EFFECTS ON GENITALIA 7 (SMG7). TDM1 attracts eIF4F, the main translation initiation complex, temporarily sequestering it in P-bodies and inhibiting translation. The failure of tdm1 mutants to terminate meiosis can be overcome by chemical inhibition of translation. We propose that TDM1-containing P-bodies down-regulate expression of meiotic transcripts to facilitate transition of cell fates to postmeiotic gametophyte differentiation.

Návaznosti

EF15_003/0000479, projekt VaV

Název: Regulace rostlinné meiózy

90129, velká výzkumná infrastruktura

Název: Czech-BioImaging II

Citovat

CAIRO CALZADA, Albert, Anna VARGOVÁ, Neha SHUKLA, Claudio CAPITAO, Pavlína MIKULKOVÁ, Soňa VALUCHOVÁ, Jana PEČINKOVÁ, Petra BULANKOVA a Karel ŘÍHA. Meiotic exit in Arabidopsis is driven by P-body-mediated inhibition of translation. Science. WASHINGTON: AMER ASSOC ADVANCEMENT SCIENCE, 2022, roč. 377, č. 6606, s. 629-634. ISSN 0036-8075. Dostupné z: https://dx.doi.org/10.1126/science.abo0904.

@article{2240870,
   author = {Cairo Calzada, Albert and Vargová, Anna and Shukla, Neha and Capitao, Claudio and Mikulková, Pavlína and Valuchová, Soňa and Pečinková, Jana and Bulankova, Petra and Říha, Karel},
   article_location = {WASHINGTON},
   article_number = {6606},
   doi = {http://dx.doi.org/10.1126/science.abo0904},
   keywords = {MESSENGER-RNA DECAY; SMG7; PROGRAM; PROTEIN; MEIOSIS; REVEALS;BODIES},
   language = {eng},
   issn = {0036-8075},
   journal = {Science},
   title = {Meiotic exit in Arabidopsis is driven by P-body-mediated inhibition of translation},
   url = {https://www.science.org/doi/10.1126/science.abo0904},
   volume = {377},
   year = {2022}
}

TY  - JOUR
ID  - 2240870
AU  - Cairo Calzada, Albert - Vargová, Anna - Shukla, Neha - Capitao, Claudio - Mikulková, Pavlína - Valuchová, Soňa - Pečinková, Jana - Bulankova, Petra - Říha, Karel
PY  - 2022
TI  - Meiotic exit in Arabidopsis is driven by P-body-mediated inhibition of translation
JF  - Science
VL  - 377
IS  - 6606
SP  - 629-634
EP  - 629-634
PB  - AMER ASSOC ADVANCEMENT SCIENCE
SN  - 00368075
KW  - MESSENGER-RNA DECAY
KW  - SMG7
KW  - PROGRAM
KW  - PROTEIN
KW  - MEIOSIS
KW  - REVEALS;BODIES
UR  - https://www.science.org/doi/10.1126/science.abo0904
N2  - Meiosis, at the transition between diploid and haploid life cycle phases, is accompanied by reprograming of cell division machinery and followed by a transition back to mitosis. We show that, in Arabidopsis, this transition is driven by inhibition of translation, achieved by a mechanism that involves processing bodies (P-bodies). During the second meiotic division, the meiosis-specific protein THREE-DIVISION MUTANT 1 (TDM1) is incorporated into P-bodies through interaction with SUPPRESSOR WITH MORPHOGENETIC EFFECTS ON GENITALIA 7 (SMG7). TDM1 attracts eIF4F, the main translation initiation complex, temporarily sequestering it in P-bodies and inhibiting translation. The failure of tdm1 mutants to terminate meiosis can be overcome by chemical inhibition of translation. We propose that TDM1-containing P-bodies down-regulate expression of meiotic transcripts to facilitate transition of cell fates to postmeiotic gametophyte differentiation.
ER  -

CAIRO CALZADA, Albert, Anna VARGOVÁ, Neha SHUKLA, Claudio CAPITAO, Pavlína MIKULKOVÁ, Soňa VALUCHOVÁ, Jana PEČINKOVÁ, Petra BULANKOVA a Karel ŘÍHA. Meiotic exit in Arabidopsis is driven by P-body-mediated inhibition of translation. \textit{Science}. WASHINGTON: AMER ASSOC ADVANCEMENT SCIENCE, 2022, roč.~377, č.~6606, s.~629-634. ISSN~0036-8075. Dostupné z: https://dx.doi.org/10.1126/science.abo0904.

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