Meiotic exit in Arabidopsis is driven by P-body-mediated
inhibition of translation

J 2022

Meiotic exit in Arabidopsis is driven by P-body-mediated inhibition of translation

CAIRO CALZADA, Albert; Anna VARGOVÁ; Neha SHUKLA; Claudio CAPITAO; Pavlína MIKULKOVÁ et. al.

Základní údaje

Originální název

Meiotic exit in Arabidopsis is driven by P-body-mediated inhibition of translation

Autoři

CAIRO CALZADA, Albert (724 Španělsko, domácí); Anna VARGOVÁ (703 Slovensko, domácí); Neha SHUKLA (356 Indie, domácí); Claudio CAPITAO; Pavlína MIKULKOVÁ (203 Česká republika, domácí); Soňa VALUCHOVÁ (703 Slovensko, domácí); Jana PEČINKOVÁ (203 Česká republika, domácí); Petra BULANKOVA a Karel ŘÍHA (203 Česká republika, garant, domácí)

Vydání

Science, WASHINGTON, AMER ASSOC ADVANCEMENT SCIENCE, 2022, 0036-8075

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10608 Biochemistry and molecular biology

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 56.900

Kód RIV

RIV/00216224:14740/22:00127511

Organizační jednotka

Středoevropský technologický institut

DOI

https://doi.org/10.1126/science.abo0904

UT WoS

000837874700039

EID Scopus

2-s2.0-85135422039

Klíčová slova anglicky

MESSENGER-RNA DECAY; SMG7; PROGRAM; PROTEIN; MEIOSIS; REVEALS;BODIES

Štítky

CF CELLIM, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 8. 10. 2024 10:31, Ing. Martina Blahová

Anotace

V originále

Meiosis, at the transition between diploid and haploid life cycle phases, is accompanied by reprograming of cell division machinery and followed by a transition back to mitosis. We show that, in Arabidopsis, this transition is driven by inhibition of translation, achieved by a mechanism that involves processing bodies (P-bodies). During the second meiotic division, the meiosis-specific protein THREE-DIVISION MUTANT 1 (TDM1) is incorporated into P-bodies through interaction with SUPPRESSOR WITH MORPHOGENETIC EFFECTS ON GENITALIA 7 (SMG7). TDM1 attracts eIF4F, the main translation initiation complex, temporarily sequestering it in P-bodies and inhibiting translation. The failure of tdm1 mutants to terminate meiosis can be overcome by chemical inhibition of translation. We propose that TDM1-containing P-bodies down-regulate expression of meiotic transcripts to facilitate transition of cell fates to postmeiotic gametophyte differentiation.

Návaznosti

EF15_003/0000479, projekt VaV

Název: Regulace rostlinné meiózy

90129, velká výzkumná infrastruktura

Název: Czech-BioImaging II

Citovat

CAIRO CALZADA, Albert; Anna VARGOVÁ; Neha SHUKLA; Claudio CAPITAO; Pavlína MIKULKOVÁ; Soňa VALUCHOVÁ; Jana PEČINKOVÁ; Petra BULANKOVA a Karel ŘÍHA. Meiotic exit in Arabidopsis is driven by P-body-mediated inhibition of translation. Science. WASHINGTON: AMER ASSOC ADVANCEMENT SCIENCE, 2022, roč. 377, č. 6606, s. 629-634. ISSN 0036-8075. Dostupné z: https://doi.org/10.1126/science.abo0904.

@article{2240870,
   author = {Cairo Calzada, Albert and Vargová, Anna and Shukla, Neha and Capitao, Claudio and Mikulková, Pavlína and Valuchová, Soňa and Pečinková, Jana and Bulankova, Petra and Říha, Karel},
   article_location = {WASHINGTON},
   article_number = {6606},
   doi = {https://doi.org/10.1126/science.abo0904},
   keywords = {MESSENGER-RNA DECAY; SMG7; PROGRAM; PROTEIN; MEIOSIS; REVEALS;BODIES},
   language = {eng},
   issn = {0036-8075},
   journal = {Science},
   title = {Meiotic exit in Arabidopsis is driven by P-body-mediated inhibition of translation},
   url = {https://www.science.org/doi/10.1126/science.abo0904},
   volume = {377},
   year = {2022}
}

TY  - JOUR
ID  - 2240870
AU  - Cairo Calzada, Albert - Vargová, Anna - Shukla, Neha - Capitao, Claudio - Mikulková, Pavlína - Valuchová, Soňa - Pečinková, Jana - Bulankova, Petra - Říha, Karel
PY  - 2022
TI  - Meiotic exit in Arabidopsis is driven by P-body-mediated inhibition of translation
JF  - Science
VL  - 377
IS  - 6606
SP  - 629-634
EP  - 629-634
PB  - AMER ASSOC ADVANCEMENT SCIENCE
SN  - 00368075
KW  - MESSENGER-RNA DECAY
KW  - SMG7
KW  - PROGRAM
KW  - PROTEIN
KW  - MEIOSIS
KW  - REVEALS;BODIES
UR  - https://www.science.org/doi/10.1126/science.abo0904
N2  - Meiosis, at the transition between diploid and haploid life cycle phases, is accompanied by reprograming of cell division machinery and followed by a transition back to mitosis. We show that, in Arabidopsis, this transition is driven by inhibition of translation, achieved by a mechanism that involves processing bodies (P-bodies). During the second meiotic division, the meiosis-specific protein THREE-DIVISION MUTANT 1 (TDM1) is incorporated into P-bodies through interaction with SUPPRESSOR WITH MORPHOGENETIC EFFECTS ON GENITALIA 7 (SMG7). TDM1 attracts eIF4F, the main translation initiation complex, temporarily sequestering it in P-bodies and inhibiting translation. The failure of tdm1 mutants to terminate meiosis can be overcome by chemical inhibition of translation. We propose that TDM1-containing P-bodies down-regulate expression of meiotic transcripts to facilitate transition of cell fates to postmeiotic gametophyte differentiation.
ER  -

CAIRO CALZADA, Albert; Anna VARGOVÁ; Neha SHUKLA; Claudio CAPITAO; Pavlína MIKULKOVÁ; Soňa VALUCHOVÁ; Jana PEČINKOVÁ; Petra BULANKOVA a Karel ŘÍHA. Meiotic exit in Arabidopsis is driven by P-body-mediated inhibition of translation. \textit{Science}. WASHINGTON: AMER ASSOC ADVANCEMENT SCIENCE, 2022, roč.~377, č.~6606, s.~629-634. ISSN~0036-8075. Dostupné z: https://doi.org/10.1126/science.abo0904.

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