C 2022

Dental Stem Cells: Developmental Aspects

KŘIVÁNEK, Jan a Kaj FRIED

Základní údaje

Originální název

Dental Stem Cells: Developmental Aspects

Autoři

KŘIVÁNEK, Jan a Kaj FRIED

Vydání

1st Edition. Berlin, Germany, Cell-to-Cell Communication: Cell-Atlas – Visual Biology in Oral Medicine, od s. 55-64, 10 s. Cell-to-Cell Communication, Volume 7, 2022

Nakladatel

Quintessence Publishing Deutschland

Další údaje

Jazyk

angličtina

Typ výsledku

Kapitola resp. kapitoly v odborné knize

Obor

10601 Cell biology

Stát vydavatele

Německo

Utajení

není předmětem státního či obchodního tajemství

Forma vydání

tištěná verze "print"

Odkazy

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/22:00127699

Organizační jednotka

Lékařská fakulta

ISBN

978-1-78698-107-3

Klíčová slova anglicky

dental stem cells

Štítky

Příznaky

Mezinárodní význam, Recenzováno
Změněno: 15. 3. 2023 13:23, Mgr. Tereza Miškechová

Anotace

V originále

Teeth in mammals develop through an interaction between cells of the ectoderm of the first pharyngeal arch in the fetus and neural crest–derived ectomesenchyme. After initiation, this process continues throughout human fetal life and is eventually finalized before adulthood, when progenitor cells vanish. The major types of basic cells involved have been identified for quite some time. However, not until recently has some light been shed on the stem cell heterogeneity in these populations. This heterogeneity reflects the mechanisms of tooth growth and pertains, among other things, to clonal development and to the identities of rare and transient cell types. Histologic identification cannot be made using pure morphologic criteria but requires specific molecular in situ protein or messenger RNA (mRNA) detection. Much of what we know regarding dental stem cells (first mentioned by E. Haeckel, 1868) derives from experimental studies with a focus on the self-renewing rodent incisor. Ample evidence indicates that this is a reasonable model for studies of tooth development in humans. However, human-specific patterns of cellular organization are clearly discernible, with subpopulations that probably contribute to human tooth development, homeostasis, and progression of disease in unique ways.

Přiložené soubory

Cell-to-Cell_Communication_Cell-Atlas_-_Visual_Biology_in_Oral_Medicine.pdf
Požádat o autorskou verzi souboru