Další formáty:
BibTeX
LaTeX
RIS
@proceedings{2245100,
author = {Damborská, Alena and Svěrák, Tomáš and Lamoš, Martin and Linhartová, Pavla},
booktitle = {50 Years of Microstates, 31 August 2022 – 3 September 2022, Bern},
keywords = {functional brain microstates; borderline personality disorder},
language = {eng},
title = {Functional brain microstates in patients with borderline personality disorder},
url = {https://www.conftool.com/50yom2022/index.php?page=browseSessions&form_session=31},
year = {2022}
}
TY - CONF
ID - 2245100
AU - Damborská, Alena - Svěrák, Tomáš - Lamoš, Martin - Linhartová, Pavla
PY - 2022
TI - Functional brain microstates in patients with borderline personality disorder
KW - functional brain microstates
KW - borderline personality disorder
UR - https://www.conftool.com/50yom2022/index.php?page=browseSessions&form_session=31
N2 - Introduction: Borderline personality disorder (BPD) is a devastating pervasive mental disorder that includes self-harming and suicidal behavior. Recent studies suggest impaired resting-state large-scale brain networks in fronto-limbic circuits in patients with BPD. The large-scale brain network activity in millisecond range can be studied with electroencephalography (EEG) using an analysis of functional brain microstates. A microstate is a global state of brain activity lasting around 100 ms characterized with a stable potential scalp topography. Microstate analysis has not been used yet to identify EEG correlates of neural abnormalities in BPD. The aim of the study is to assess dynamics of microstates in BPD. Method: Thirty one BPD adult patients and thirty one age and sex matched healthy controls underwent six minute resting-state high-density EEG recording. We explored between-group differences in temporal parameters of microstates using Cartool software. Results: Six microstates with different scalp topographies were identified using data-driven approach across all subjects. The presence of the microstate with left anterior and right posterior potential maxima, a topography resembling that previously reported as B, was significantly decreased in patients vs. healthy controls (p ≤ 0.05) as revealed by lower duration, time coverage, and occurrence. Conclusion: Our findings suggest a decreased presence of microstate B in patients with BPD. This microstate was previously associated with networks related to visual processing and visualization thoughts. Temporal dynamics of these network activity might therefore be impaired in patients with BPD. This work was supported by grant MZ ČR (NU20-04-00410) and grant MZ ČR – RVO (FNBr, 65269705).
ER -
DAMBORSKÁ, Alena, Tomáš SVĚRÁK, Martin LAMOŠ a Pavla LINHARTOVÁ. Functional brain microstates in patients with borderline personality disorder. In \textit{50 Years of Microstates, 31 August 2022 – 3 September 2022, Bern}. 2022.
|
