Další formáty:
BibTeX
LaTeX
RIS
@article{2247549, author = {Vaníčková, Lucie and Do, Tomáš and Vejvodová, Markéta and Horák, Vratislav and Hubálek, Martin and Emri, Gabriella and Zemánková, Kristýna and Pavelicová, Kristýna and Křížková, Soňa and Faltusová, Veronika and Pompeiano, Antonio and Vaculovičová, Markéta and Zítka, Ondřej and Vaculovič, Tomáš and Adam, Vojtěch}, article_number = {April}, doi = {http://dx.doi.org/10.1016/j.ijbiomac.2022.01.139}, keywords = {Melanoma; Mass spectrometry; MeLiM}, language = {eng}, issn = {0141-8130}, journal = {International Journal of Biological Macromolecules}, title = {Mapping of MeLiM melanoma combining ICP-MS and MALDI-MSI methods}, url = {https://doi.org/10.1016/j.ijbiomac.2022.01.139}, volume = {203}, year = {2022} }
TY - JOUR ID - 2247549 AU - Vaníčková, Lucie - Do, Tomáš - Vejvodová, Markéta - Horák, Vratislav - Hubálek, Martin - Emri, Gabriella - Zemánková, Kristýna - Pavelicová, Kristýna - Křížková, Soňa - Faltusová, Veronika - Pompeiano, Antonio - Vaculovičová, Markéta - Zítka, Ondřej - Vaculovič, Tomáš - Adam, Vojtěch PY - 2022 TI - Mapping of MeLiM melanoma combining ICP-MS and MALDI-MSI methods JF - International Journal of Biological Macromolecules VL - 203 IS - April SP - 583-592 EP - 583-592 PB - Elsevier SN - 01418130 KW - Melanoma KW - Mass spectrometry KW - MeLiM UR - https://doi.org/10.1016/j.ijbiomac.2022.01.139 N2 - Here we developed a powerful tool for comprehensive data collection and mapping of molecular and elemental signatures in the Melanoma-bearing Libechov Minipig (MeLiM) model. The combination of different mass spectrometric methods allowed for detail investigation of specific melanoma markers and elements and their spatial distribution in tissue sections. MALDI-MSI combined with HPLC-MS/MS analyses resulted in identification of seven specific proteins, S100A12, CD163, MMP-2, galectin-1, tenascin, resistin and PCNA that were presented in the melanoma signatures. Furthermore, the ICP-MS method allowed for spatial detection of zinc, calcium, copper, and iron elements linked with the allocation of the specific binding proteins. ER -
VANÍČKOVÁ, Lucie, Tomáš DO, Markéta VEJVODOVÁ, Vratislav HORÁK, Martin HUBÁLEK, Gabriella EMRI, Kristýna ZEMÁNKOVÁ, Kristýna PAVELICOVÁ, Soňa KŘÍŽKOVÁ, Veronika FALTUSOVÁ, Antonio POMPEIANO, Markéta VACULOVIČOVÁ, Ondřej ZÍTKA, Tomáš VACULOVIČ a Vojtěch ADAM. Mapping of MeLiM melanoma combining ICP-MS and MALDI-MSI methods. \textit{International Journal of Biological Macromolecules}. Elsevier, 2022, roč.~203, April, s.~583-592. ISSN~0141-8130. Dostupné z: https://dx.doi.org/10.1016/j.ijbiomac.2022.01.139.
|