a 2022

Izokibep, a Novel IL-17A Inhibitor, Improves Patient-reported Outcomes-16-Week Results from a Placebo-controlled Phase 2 Study in Patients with Active Psoriatic Arthritis

TAYLOR, Peter, Frank BEHRENS, Philip J. MEASE, Dieter WETZEL, Paul PELOSO et. al.

Basic information

Original name

Izokibep, a Novel IL-17A Inhibitor, Improves Patient-reported Outcomes-16-Week Results from a Placebo-controlled Phase 2 Study in Patients with Active Psoriatic Arthritis

Authors

TAYLOR, Peter, Frank BEHRENS, Philip J. MEASE, Dieter WETZEL, Paul PELOSO, Nicolai BRUN, Brian WIENS, Jan BRANDTJUERGENS, Edit DRESCHER, Eva DOKOUPILOVÁ (203 Czech Republic, belonging to the institution), Anna ROWINSKA-OSUCH, Nadia Abdel-Kader MARTIN and Kurt DE VLAM

Edition

2022

Other information

Language

English

Type of outcome

Konferenční abstrakt

Field of Study

30104 Pharmacology and pharmacy

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 13.300

RIV identification code

RIV/00216224:14160/22:00128083

Organization unit

Faculty of Pharmacy

ISSN

UT WoS

000877386500199

Keywords in English

Izokibep; IL-17A inhibitor; patient outcomes; psoriatic arthriris; clinical trial

Tags

Tags

International impact
Změněno: 19/1/2023 09:26, JUDr. Sabina Krejčiříková

Abstract

V originále

Izokibep is a unique IL-17A inhibitor with high potency and small molecular size designed to overcome the limitations of monoclonal antibodies. IL-17 is a key driver of the PsA disease process, which greatly impacts patients’ physical function, vitality, social participation, mood, and quality of life. Here, we report 16-week results of izokibep on patient-reported outcomes (PROs) in adult patients with active PsA.