Baylisascaris transfuga (Ascaridoidea, Nematoda) from European
brown bear (Ursus arctos) causing larva migrans in laboratory
mice with clinical manifestation

J 2022

Baylisascaris transfuga (Ascaridoidea, Nematoda) from European brown bear (Ursus arctos) causing larva migrans in laboratory mice with clinical manifestation

JURÁNKOVÁ, Jana, Lada HOFMANNOVÁ, Lucia FRGELECOVÁ, Ondřej DANĚK, David MODRÝ et. al.

Základní údaje

Originální název

Baylisascaris transfuga (Ascaridoidea, Nematoda) from European brown bear (Ursus arctos) causing larva migrans in laboratory mice with clinical manifestation

Autoři

JURÁNKOVÁ, Jana (garant), Lada HOFMANNOVÁ, Lucia FRGELECOVÁ, Ondřej DANĚK a David MODRÝ (203 Česká republika, domácí)

Vydání

Parasitology research, Springer, 2022, 0932-0113

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30310 Parasitology

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 2.000

Kód RIV

RIV/00216224:14310/22:00128168

Organizační jednotka

Přírodovědecká fakulta

DOI

http://dx.doi.org/10.1007/s00436-021-07417-z

UT WoS

000738437100003

Klíčová slova anglicky

Baylisascaris transfuga; Brown bear; Larva migrans; Mice

Štítky

rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 23. 1. 2023 15:52, Mgr. Marie Novosadová Šípková, DiS.

Anotace

V originále

Due to the recent recovery of brown bear populations in Central Europe, information about their ascarid parasite, Baylisascaris transfuga is necessary as the parasite represents a part of natural ecological networks. B. transfuga can lead to larva migrans syndrome in accidental hosts, but its zoonotic potential has not been confirmed. The resent study compares development of larva migrans in infected mice inoculated with two infectious doses (ID 200 and ID 2000) of B. transfuga embryonated eggs, and the clinical manifestation to evaluate the pathogenicity of the larvae. Histopathology revealed that the liver was the most severely infected organ. The moderately infected organs included lung, brain, skeletal muscles and jejunum and the less infected ones were the eyes, heart, kidneys and spleen. The high pathogenicity of B. transfuga to mice was reflected in high mortality (33,3%) after infection, with mortality increasing with higher infectious dose. The results extend the knowledge of the interaction of B. transfuga and its aberrant hosts and contribute to the understanding of the epidemiology and transmission of this bears roundworm.

Citovat

JURÁNKOVÁ, Jana, Lada HOFMANNOVÁ, Lucia FRGELECOVÁ, Ondřej DANĚK a David MODRÝ. Baylisascaris transfuga (Ascaridoidea, Nematoda) from European brown bear (Ursus arctos) causing larva migrans in laboratory mice with clinical manifestation. Parasitology research. Springer, 2022, roč. 121, č. 2, s. 645-651. ISSN 0932-0113. Dostupné z: https://dx.doi.org/10.1007/s00436-021-07417-z.

@article{2248047,
   author = {Juránková, Jana and Hofmannová, Lada and Frgelecová, Lucia and Daněk, Ondřej and Modrý, David},
   article_number = {2},
   doi = {http://dx.doi.org/10.1007/s00436-021-07417-z},
   keywords = {Baylisascaris transfuga; Brown bear; Larva migrans; Mice},
   language = {eng},
   issn = {0932-0113},
   journal = {Parasitology research},
   title = {Baylisascaris transfuga (Ascaridoidea, Nematoda) from European brown bear (Ursus arctos) causing larva migrans in laboratory mice with clinical manifestation},
   url = {https://doi.org/10.1007/s00436-021-07417-z},
   volume = {121},
   year = {2022}
}

TY  - JOUR
ID  - 2248047
AU  - Juránková, Jana - Hofmannová, Lada - Frgelecová, Lucia - Daněk, Ondřej - Modrý, David
PY  - 2022
TI  - Baylisascaris transfuga (Ascaridoidea, Nematoda) from European brown bear (Ursus arctos) causing larva migrans in laboratory mice with clinical manifestation
JF  - Parasitology research
VL  - 121
IS  - 2
SP  - 645-651
EP  - 645-651
PB  - Springer
SN  - 09320113
KW  - Baylisascaris transfuga
KW  - Brown bear
KW  - Larva migrans
KW  - Mice
UR  - https://doi.org/10.1007/s00436-021-07417-z
N2  - Due to the recent recovery of brown bear populations in Central Europe, information about their ascarid parasite, Baylisascaris transfuga is necessary as the parasite represents a part of natural ecological networks. B. transfuga can lead to larva migrans syndrome in accidental hosts, but its zoonotic potential has not been confirmed. The resent study compares development of larva migrans in infected mice inoculated with two infectious doses (ID 200 and ID 2000) of B. transfuga embryonated eggs, and the clinical manifestation to evaluate the pathogenicity of the larvae. Histopathology revealed that the liver was the most severely infected organ. The moderately infected organs included lung, brain, skeletal muscles and jejunum and the less infected ones were the eyes, heart, kidneys and spleen. The high pathogenicity of B. transfuga to mice was reflected in high mortality (33,3%) after infection, with mortality increasing with higher infectious dose. The results extend the knowledge of the interaction of B. transfuga and its aberrant hosts and contribute to the understanding of the epidemiology and transmission of this bears roundworm.
ER  -

JURÁNKOVÁ, Jana, Lada HOFMANNOVÁ, Lucia FRGELECOVÁ, Ondřej DANĚK a David MODRÝ. Baylisascaris transfuga (Ascaridoidea, Nematoda) from European brown bear (Ursus arctos) causing larva migrans in laboratory mice with clinical manifestation. \textit{Parasitology research}. Springer, 2022, roč.~121, č.~2, s.~645-651. ISSN~0932-0113. Dostupné z: https://dx.doi.org/10.1007/s00436-021-07417-z.

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