Signaling pathways in cutaneous wound healing

J 2022

Signaling pathways in cutaneous wound healing

KRIŽANOVÁ, Oľga, Adela PENESOVA, Jozef SOKOL, Alica HOKYNKOVÁ, Amir SAMADIAN et. al.

Základní údaje

Originální název

Signaling pathways in cutaneous wound healing

Autoři

KRIŽANOVÁ, Oľga (703 Slovensko, domácí), Adela PENESOVA, Jozef SOKOL, Alica HOKYNKOVÁ (703 Slovensko, domácí), Amir SAMADIAN (364 Írán, domácí) a Petr BABULA (203 Česká republika, garant, domácí)

Vydání

Frontiers in Physiology, Lausanne, FRONTIERS MEDIA SA, 2022, 1664-042X

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30105 Physiology

Stát vydavatele

Švýcarsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 4.000

Kód RIV

RIV/00216224:14110/22:00129728

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.3389/fphys.2022.1030851

UT WoS

000895789500001

Klíčová slova anglicky

wound healing; gasotransmitters; calcium; hydrogen peroxide; diabetes mellitus

Štítky

14110229, 14110515, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 24. 11. 2023 07:27, Mgr. Tereza Miškechová

Anotace

V originále

Wound healing is a very complex process, where variety of different pathways is activated, depending on the phase of healing. Improper or interrupted healing might result in development of chronic wounds. Therefore, novel approaches based on detailed knowledge of signalling pathways that are activated during acute or chronic cutaneous wound healing enables quicker and more effective healing. This review outlined new possibilities of cutaneous wound healing by modulation of some signalling molecules, e.g., gasotransmitters, or calcium. Special focus is given to gasotransmitters, since these bioactive signalling molecules that can freely diffuse into the cell and exert antioxidative effects. Calcium is an important booster of immune system and it can significantly contribute to healing process. Special interest is given to chronic wounds caused by diabetes mellitus and overcoming problems with the inflammation.

Návaznosti

NU21-09-00541, projekt VaV

Název: Role oxidativního stresu při hojení dekubitů u pacientů s míšní lézí

Investor: Ministerstvo zdravotnictví ČR, Role oxidativního stresu při hojení dekubitů u pacientů s míšní lézí, Podprogram 1 - standardní

Citovat

KRIŽANOVÁ, Oľga, Adela PENESOVA, Jozef SOKOL, Alica HOKYNKOVÁ, Amir SAMADIAN a Petr BABULA. Signaling pathways in cutaneous wound healing. Frontiers in Physiology. Lausanne: FRONTIERS MEDIA SA, 2022, roč. 13, November 2022, s. 1-11. ISSN 1664-042X. Dostupné z: https://dx.doi.org/10.3389/fphys.2022.1030851.

@article{2248069,
   author = {Križanová, Oľga and Penesova, Adela and Sokol, Jozef and Hokynková, Alica and Samadian, Amir and Babula, Petr},
   article_location = {Lausanne},
   article_number = {November 2022},
   doi = {http://dx.doi.org/10.3389/fphys.2022.1030851},
   keywords = {wound healing; gasotransmitters; calcium; hydrogen peroxide; diabetes mellitus},
   language = {eng},
   issn = {1664-042X},
   journal = {Frontiers in Physiology},
   title = {Signaling pathways in cutaneous wound healing},
   url = {https://www.frontiersin.org/articles/10.3389/fphys.2022.1030851/full},
   volume = {13},
   year = {2022}
}

TY  - JOUR
ID  - 2248069
AU  - Križanová, Oľga - Penesova, Adela - Sokol, Jozef - Hokynková, Alica - Samadian, Amir - Babula, Petr
PY  - 2022
TI  - Signaling pathways in cutaneous wound healing
JF  - Frontiers in Physiology
VL  - 13
IS  - November 2022
SP  - 1-11
EP  - 1-11
PB  - FRONTIERS MEDIA SA
SN  - 1664042X
KW  - wound healing
KW  - gasotransmitters
KW  - calcium
KW  - hydrogen peroxide
KW  - diabetes mellitus
UR  - https://www.frontiersin.org/articles/10.3389/fphys.2022.1030851/full
N2  - Wound healing is a very complex process, where variety of different pathways is activated, depending on the phase of healing. Improper or interrupted healing might result in development of chronic wounds. Therefore, novel approaches based on detailed knowledge of signalling pathways that are activated during acute or chronic cutaneous wound healing enables quicker and more effective healing. This review outlined new possibilities of cutaneous wound healing by modulation of some signalling molecules, e.g., gasotransmitters, or calcium. Special focus is given to gasotransmitters, since these bioactive signalling molecules that can freely diffuse into the cell and exert antioxidative effects. Calcium is an important booster of immune system and it can significantly contribute to healing process. Special interest is given to chronic wounds caused by diabetes mellitus and overcoming problems with the inflammation.
ER  -

KRIŽANOVÁ, Oľga, Adela PENESOVA, Jozef SOKOL, Alica HOKYNKOVÁ, Amir SAMADIAN a Petr BABULA. Signaling pathways in cutaneous wound healing. \textit{Frontiers in Physiology}. Lausanne: FRONTIERS MEDIA SA, 2022, roč.~13, November 2022, s.~1-11. ISSN~1664-042X. Dostupné z: https://dx.doi.org/10.3389/fphys.2022.1030851.

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