Flavonoids exert potential in the management of hypertensive
disorders in pregnancy

J 2022

Flavonoids exert potential in the management of hypertensive disorders in pregnancy

MAZURAKOVA, Alena, Lenka KOKLESOVA, Marek SAMEC, Erik KUDELA, Jana SIVAKOVA et. al.

Základní údaje

Originální název

Flavonoids exert potential in the management of hypertensive disorders in pregnancy

Autoři

Vydání

PREGNANCY HYPERTENSION-AN INTERNATIONAL JOURNAL OF WOMENS CARDIOVASCULAR HEALTH, OXFORD, ELSEVIER SCI LTD, 2022, 2210-7789

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30201 Cardiac and Cardiovascular systems

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 2.200

Kód RIV

RIV/00216224:14110/22:00128207

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1016/j.preghy.2022.06.007

UT WoS

000835961500002

Klíčová slova anglicky

Flavonoids; Hypertensive disorders; Pregnancy; Preeclampsia

Štítky

14110116, 14110121, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 11. 1. 2024 11:59, Mgr. Tereza Miškechová

Anotace

V originále

Hypertensive disorders in pregnancy represent severe complications of pregnancy, which, if not treated, can result in serious health consequences for the mother and the child. Flavonoids are bioactive secondary metabolites commonly found in fruits, vegetables, green tea, whole grains, and medicinal plants. Flavonoids exert potent protective efficacy in experimental models of hypertensive disorders in pregnancy, especially preeclampsia, demonstrated through their capacity to modulate inflammatory responses, oxidative stress, and vascular dysfunction. In addition to their potential as therapeutics, flavonoids or flavonoid-rich food could be helpful to decrease the risk of hypertensive disorders in pregnancy when included in the diet pattern before and during pregnancy. However, the clinical evaluation of the potential capacity of flavonoids in hypertensive disorders in pregnancy is insufficient. Due to promising results from experimental studies, we highlight the need for the evaluation of flavonoids also in an appropriate clinical setting, which can be, together with proper preventive strategies, helpful in the overall management of hypertensive disorders in pregnancy.

Citovat

MAZURAKOVA, Alena, Lenka KOKLESOVA, Marek SAMEC, Erik KUDELA, Jana SIVAKOVA, Terezia PRIBULOVA, Martin Jozef PEC, Martin PEC, Martin KELLO, Dietrich BUSSELBERG, Olga GOLUBNITSCHAJA, Ludovit GASPAR, Martin CAPRNDA, Mariusz ADAMEK, Robert PROSECKÝ, Elmira EMINOVA, Denis BARANENKO, Peter KRUŽLIAK, Peter KUBATKA a Kamil BIRINGER. Flavonoids exert potential in the management of hypertensive disorders in pregnancy. PREGNANCY HYPERTENSION-AN INTERNATIONAL JOURNAL OF WOMENS CARDIOVASCULAR HEALTH. OXFORD: ELSEVIER SCI LTD, 2022, roč. 29, August 2022, s. 72-85. ISSN 2210-7789. Dostupné z: https://dx.doi.org/10.1016/j.preghy.2022.06.007.

@article{2249048,
   author = {Mazurakova, Alena and Koklesova, Lenka and Samec, Marek and Kudela, Erik and Sivakova, Jana and Pribulova, Terezia and Pec, Martin Jozef and Pec, Martin and Kello, Martin and Busselberg, Dietrich and Golubnitschaja, Olga and Gaspar, Ludovit and Caprnda, Martin and Adamek, Mariusz and Prosecký, Robert and Eminova, Elmira and Baranenko, Denis and Kružliak, Peter and Kubatka, Peter and Biringer, Kamil},
   article_location = {OXFORD},
   article_number = {August 2022},
   doi = {http://dx.doi.org/10.1016/j.preghy.2022.06.007},
   keywords = {Flavonoids; Hypertensive disorders; Pregnancy; Preeclampsia},
   language = {eng},
   issn = {2210-7789},
   journal = {PREGNANCY HYPERTENSION-AN INTERNATIONAL JOURNAL OF WOMENS CARDIOVASCULAR HEALTH},
   title = {Flavonoids exert potential in the management of hypertensive disorders in pregnancy},
   url = {https://www.sciencedirect.com/science/article/pii/S2210778922000642?via%3Dihub},
   volume = {29},
   year = {2022}
}

TY  - JOUR
ID  - 2249048
AU  - Mazurakova, Alena - Koklesova, Lenka - Samec, Marek - Kudela, Erik - Sivakova, Jana - Pribulova, Terezia - Pec, Martin Jozef - Pec, Martin - Kello, Martin - Busselberg, Dietrich - Golubnitschaja, Olga - Gaspar, Ludovit - Caprnda, Martin - Adamek, Mariusz - Prosecký, Robert - Eminova, Elmira - Baranenko, Denis - Kružliak, Peter - Kubatka, Peter - Biringer, Kamil
PY  - 2022
TI  - Flavonoids exert potential in the management of hypertensive disorders in pregnancy
JF  - PREGNANCY HYPERTENSION-AN INTERNATIONAL JOURNAL OF WOMENS CARDIOVASCULAR HEALTH
VL  - 29
IS  - August 2022
SP  - 72-85
EP  - 72-85
PB  - ELSEVIER SCI LTD
SN  - 22107789
KW  - Flavonoids
KW  - Hypertensive disorders
KW  - Pregnancy
KW  - Preeclampsia
UR  - https://www.sciencedirect.com/science/article/pii/S2210778922000642?via%3Dihub
N2  - Hypertensive disorders in pregnancy represent severe complications of pregnancy, which, if not treated, can result in serious health consequences for the mother and the child. Flavonoids are bioactive secondary metabolites commonly found in fruits, vegetables, green tea, whole grains, and medicinal plants. Flavonoids exert potent protective efficacy in experimental models of hypertensive disorders in pregnancy, especially preeclampsia, demonstrated through their capacity to modulate inflammatory responses, oxidative stress, and vascular dysfunction. In addition to their potential as therapeutics, flavonoids or flavonoid-rich food could be helpful to decrease the risk of hypertensive disorders in pregnancy when included in the diet pattern before and during pregnancy. However, the clinical evaluation of the potential capacity of flavonoids in hypertensive disorders in pregnancy is insufficient. Due to promising results from experimental studies, we highlight the need for the evaluation of flavonoids also in an appropriate clinical setting, which can be, together with proper preventive strategies, helpful in the overall management of hypertensive disorders in pregnancy.
ER  -

MAZURAKOVA, Alena, Lenka KOKLESOVA, Marek SAMEC, Erik KUDELA, Jana SIVAKOVA, Terezia PRIBULOVA, Martin Jozef PEC, Martin PEC, Martin KELLO, Dietrich BUSSELBERG, Olga GOLUBNITSCHAJA, Ludovit GASPAR, Martin CAPRNDA, Mariusz ADAMEK, Robert PROSECKÝ, Elmira EMINOVA, Denis BARANENKO, Peter KRUŽLIAK, Peter KUBATKA a Kamil BIRINGER. Flavonoids exert potential in the management of hypertensive disorders in pregnancy. \textit{PREGNANCY HYPERTENSION-AN INTERNATIONAL JOURNAL OF WOMENS CARDIOVASCULAR HEALTH}. OXFORD: ELSEVIER SCI LTD, 2022, roč.~29, August 2022, s.~72-85. ISSN~2210-7789. Dostupné z: https://dx.doi.org/10.1016/j.preghy.2022.06.007.

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