Contrast-induced acute kidney injury and its contemporary prevention

@article{2249072,
   author = {Sůva, Marek and Kala, Petr and Poloczek, Martin and Kaňovský, Jan and Štípal, Roman and Radvan, Martin and Hlásenský, Jiří and Hudec, Martin and Brázdil, Vojtěch and Řehořová, Jitka},
   article_location = {Lausanne},
   article_number = {December 2022},
   doi = {http://dx.doi.org/10.3389/fcvm.2022.1073072},
   keywords = {PCI; nephrotoxicity; acute kidney injury; contrast-induced acute kidney injury; chronic renal insufficiency; prevention},
   language = {eng},
   issn = {2297-055X},
   journal = {Frontiers in Cardiovascular Medicine},
   title = {Contrast-induced acute kidney injury and its contemporary prevention},
   url = {https://www.frontiersin.org/articles/10.3389/fcvm.2022.1073072/full},
   volume = {9},
   year = {2022}
}

TY  - JOUR
ID  - 2249072
AU  - Sůva, Marek - Kala, Petr - Poloczek, Martin - Kaňovský, Jan - Štípal, Roman - Radvan, Martin - Hlásenský, Jiří - Hudec, Martin - Brázdil, Vojtěch - Řehořová, Jitka
PY  - 2022
TI  - Contrast-induced acute kidney injury and its contemporary prevention
JF  - Frontiers in Cardiovascular Medicine
VL  - 9
IS  - December 2022
SP  - 1-24
EP  - 1-24
PB  - Frontiers
SN  - 2297055X
KW  - PCI
KW  - nephrotoxicity
KW  - acute kidney injury
KW  - contrast-induced acute kidney injury
KW  - chronic renal insufficiency
KW  - prevention
UR  - https://www.frontiersin.org/articles/10.3389/fcvm.2022.1073072/full
N2  - The complexity and application range of interventional and diagnostic procedures using contrast media (CM) have recently increased. This allows more patients to undergo procedures that involve CM administration. However, the intrinsic CM toxicity leads to the risk of contrast-induced acute kidney injury (CI-AKI). At present, effective therapy of CI-AKI is rather limited. Effective prevention of CI-AKI therefore becomes crucially important. This review presents an in-depth discussion of CI-AKI incidence, pathogenesis, risk prediction, current preventive strategies, and novel treatment possibilities. The review also discusses the difference between CI-AKI incidence following intraarterial and intravenous CM administration. Factors contributing to the development of CI-AKI are considered in conjunction with the mechanism of acute kidney damage. The need for ultimate risk estimation and the prediction of CI-AKI is stressed. Possibilities of CI-AKI prevention is evaluated within the spectrum of existing preventive measures aimed at reducing kidney injury. In particular, the review discusses intravenous hydration regimes and pre-treatment with statins and N-acetylcysteine. The review further focuses on emerging alternative imaging technologies, alternative intravascular diagnostic and interventional procedures, and new methods for intravenous hydration guidance; it discusses the applicability of those techniques in complex procedures and their feasibility in current practise. We put emphasis on contemporary interventional cardiology imaging methods, with a brief discussion of CI-AKI in non-vascular and non-cardiologic imaging and interventional studies.
ER  - 

SŮVA, Marek, Petr KALA, Martin POLOCZEK, Jan KAŇOVSKÝ, Roman ŠTÍPAL, Martin RADVAN, Jiří HLÁSENSKÝ, Martin HUDEC, Vojtěch BRÁZDIL a Jitka ŘEHOŘOVÁ. Contrast-induced acute kidney injury and its contemporary prevention. \textit{Frontiers in Cardiovascular Medicine}. Lausanne: Frontiers, 2022, roč.~9, December 2022, s.~1-24. ISSN~2297-055X. Dostupné z: https://dx.doi.org/10.3389/fcvm.2022.1073072.