J 2023

Prognostic value of Doppler echocardiographic coronary flow velocity assessment at rest in elderly patients

ZAGATINA, Angela, Elena KALININA, Martin CAPRNDA, Ludovit GASPAR, Katarina GAZDIKOVA et. al.

Základní údaje

Originální název

Prognostic value of Doppler echocardiographic coronary flow velocity assessment at rest in elderly patients

Autoři

ZAGATINA, Angela (garant), Elena KALININA, Martin CAPRNDA, Ludovit GASPAR, Katarina GAZDIKOVA, David ULLRICH (203 Česká republika), Robert PROSECKÝ (203 Česká republika, domácí), Luis RODRIGO a Peter KRUŽLIAK (703 Slovensko)

Vydání

Acta Cardiologica, ABINGDON, TAYLOR & FRANCIS LTD, 2023, 0001-5385

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30201 Cardiac and Cardiovascular systems

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

Impakt faktor

Impact factor: 1.600 v roce 2022

Kód RIV

RIV/00216224:14110/23:00130228

Organizační jednotka

Lékařská fakulta

UT WoS

000863716700001

Klíčová slova anglicky

Echocardiography; outcome; elderly; coronary flow; coronary Doppler

Štítky

Příznaky

Mezinárodní význam, Recenzováno
Změněno: 26. 1. 2024 10:48, Mgr. Tereza Miškechová

Anotace

V originále

Background Atherosclerosis and coronary artery disease (CAD) are a common condition and cause of death in the elderly population. There are difficulties with risk assessment in the elderly as the objectification of their symptomatic status can be challenging due to neuromuscular weakness, physical deconditioning or neurological, orthopaedic, peripheral vascular, or respiratory limitations. Non-invasive coronary artery velocity assessment by Doppler method at rest could be helpful in the elderly population. To evaluate the prognostic role of coronary artery ultrasound assessment in a non-selected elderly population in everyday clinical practice. Methods One hundred forty-five patients, aged >= 75years (99 women; 80 +/- 4 years), formed the study group. Left coronary artery flows were scanned in addition to conventional echocardiography. During a median follow-up of 26 months, 16 deaths and 2 non-fatal MI occurred. Results In multivariable analysis, maximal coronary velocity was the only independent predictor for mortality (heart rate [HR]: 1.02, 95%, CI: 1.01-1.04, p < .0005) and for mortality/MI (HR: 1.02, 95%, CI: 1.01-1.03, p < .0001). The value of 110 cm/s maximal coronary flow velocity (CFL) in the proximal segments of left arteries was the best predictor for death, sensitivity 50%, specificity 90%, p < .005. The annual mortality rate was 16.6% persons/year for patients with elevated CFL >= 110 cm/s. The value 81 cm/s was the best predictor for death/MI, sensitivity 61%, specificity 80%, p < .0005; annual mortality rate was 11.2% persons/year for patients with elevated CFL >= 81 cm/s (p < .0001). Conclusion Doppler CFL scanning during routine echocardiography is a feasible and valuable tool for assessment of short-term prognosis in elderly patients.