The Global Retinoblastoma Outcome Study: a prospective, cluster-based analysis of 4064 patients from 149 countries
Autoři
ALIA, Donjeta B, Alketa TANDILI, Luisa PAIVA, Amelia Dc WIME, Guillermo L CHANTADA, Adriana C FANDINO, Mariana SGROI, Ruzanna PAPYAN, Gevorg TAMAMYAN, Jayne E CAMUGLIA, Glen A GOLE, Antony CLARK, Geoffrey C LAM, James E ELDER, John D MCKENZIE, Sandra E STAFFIERI, Michael M JONES, Rebecca MANUDHANE, David SIA, Petra RITTER-SOVINZ, Christoph SCHWAB, Ruhengiz BALAYEVA, Zohora KHAN, Murtuza NURUDDIN, Soma R ROY, Riffat RASHID, Sadia SULTANA, Shawkat A SHAKOOR, Larisa NAUMENKO, Katsiaryna ZHILYAEVA, Paulina BARTOSZEK, Benedicte G BRICHARD, De Potter PATRICK, Amadou I Alfa BIO, Beatriz SALAS, Coleoni Suarez Maria ESTELA, Freddy B MBUMBA, Maria Teresa B C BONANOMI, Carla R. DONATO MACEDO, Nathalia D A K GRIGOROVSKI, Clarissa C D S MATTOSINHO, Luiz F TEIXEIRA, Alexander H OSCAR, Nevyana V VELEVA-KRASTEVA, Gabrielle C BOUDA, Rolande L KABORE, Remezo PHILBERT, Ted Grimbert A EVINA, Henry E NKUMBE, Pius KAMSANG, Okwen M MUYEN, Helen DIMARAS, Ashwin MALLIPATNA, Patrick HAMEL, Rosanne SUPERSTEIN, Katherine E PATON, Caron STRAHLENDORF, Jess Elio Kosh Komba PALET, Harba TYAU-TYAU, Isabel CAVIERES, Juan P LOPEZ, Joaquin OPORTO, Diego OSSANDON, Wensi CHEN, Daoman XIANG, Yi DU, Kaijun LI, Xunda JI, Jing TANG, Cairui LI, Bing XU, Jiang QIAN, Kang XUE, Xiantao SUN, Yi-Zhuo WANG, Yi ZHANG, Si-qi WU, Yishuang XIAO, Huasheng YANG, Huijing YE, Rodrigo A POLANIA, Rokia C BERETE, Line COUITCHERE, Sanja PERIC, Ernesto ALEMANY-RUBIO, Liudmira GONZALEZ-RODRIGUEZ, Rudolf AUTRATA (203 Česká republika, domácí), Tomáš KEPÁK (203 Česká republika, domácí), Pavel POCHOP, Karel SVOJGR, Pernille A GREGERSEN, Steen F URBAK, Margarita M MONTERO, Aleine BUDIONGO, Jenny M YANGA, Theophile B Kabesha AMANI, Robert M LUKAMBA, Marcel N NUMBI, Doris A CALLE JARA, Edwin G VILLACIS CHAFLA, Gissela L SANCHEZ, Sherif ABOUELNAGA, Mahmoud A AFIFI, Alaa M ELHADDAD, Amany M ALI, M. ELZEMBELY, Azza M A SAID, Othman A O ZIKO, Soad L FUENTES-ALABI, Marco A GOENZ, Katrin EERME, Artur KLETT, Diriba F HORDOFA, Aemero A MENGESHA, Sadik T SHERIEF, Tero T KIVELA, Kalle NUMMI, Nathalie CASSOUX, Laurence DESJARDINS, Ghislaine OBONO-OBIANG, Tamar KARDAVA, Zaza KHOTENASHVILI, Nikolaos E BECHRAKIS, Eva M BIEWALD, Sabrina SCHLUETER, Petra KETTELER, Doreen AMANKWAA-FREMPONG, Vera A ESSUMAN, Vivian PAINTSIL, Lorna A RENNER, Amanda ALEJOS, Ana V GIRON, Yvania Alfonso CARRERAS, Ligia D FU, Carlos MALDONADO, Emily S WONG, Jason C YAM, Monika CSOKA, Erika MAKA, Priyanka AGGARWAL, Vineeta GUPTA, Anirban BHADURI, Arpita BHATTACHARYYA, Anirban DAS, Bhavna CHAWLA, Pranab DAS, Sima DAS, Himika GUPTA, Sanjiv GUPTA, Nishant VERMA, Swathi KALIKI, Vikas KHETAN, Puja MAITRA, Amita MAHAJAN, Vikas MENON, Divyansh K C MISHRA, Mahesh Shanmugam PALANIVELU, Rajesh RAMANJULU, Sangeeta S MUDALIAR, Akshay Gopinathan NAIR, Sundaram NATARAJAN, Rachna SETH, Usha SINGH, Sunil BHAT, Gagan DUDEJA, Devjyoti TRIPATHY, Indonesia Marliyanti N R AKIB, Halimah PAGARRA, Primawita O AMIRUDDIN, Mayasari W KUNTORINI, Inggar ARMYTASARI, Eddy SUPRIYADI, I Wayan Eka SUTYAWAN, Putu YULIAWATI, Delfitri LUTFI, Hendrian D SOEBAGJO, Ardizal RAHMAN, Rita S SITORUS, Andi A VICTOR, Edi S TEHUTERU, Widiarti WIDIARTI, Yetty M NENCY, Mohammad FARANOUSH, Azim MEHRVAR, Maryam TASHVIGHI, Ahad SEDAGHAT, Fariba GHASSEMI, Alireza KHODABANDE, Rula A ABDULQADER, Athar A S M AL-SHAHEEN, H. AL ANI MOUROGE, Huda HAYDAR, Safaa A F AL-BADRI, Mazin F AL-JADIRY, Ahmed H SABHAN, Usama AL-JUMAILY, Ali A R M AL-MAFRACHI, Entissar H AL-SHAMMARY, Allawi N Hussein AL-JANABI, Ali O QADIR, Michael CAPRA, Sharon BLUM, Nir GOMEL, Ido Didi FABIAN (garant), Hila GOLDBERG, Noa KAPELUSHNIK, Shiran MADGAR, Victoria VISHNEVSKIA-DAI, Shahar FRENKEL, Jacob PEER, Malka GORFINE, David REFAELI, David M STEINBERG, Yotam LAVY, Helen TOLEDANO, Shani CASPI, De Francesco SONIA, Theodora HADJISTILIANOU, Russo IDA, Paola VALENTE, Edoardo MIDENA, Raffaele PARROZZANI, Kristin E COWAN-LYN, Leon O VAUGHAN, Shigenobu SUZUKI, Mona T MOHAMMAD, Yacoub A YOUSEF, Lyazat MANZHUOVA, Rose ATSIAYA, Ibrahim O MATENDE, Ainura S BEGIMKULOVA, Emil K MAKIMBETOV, Jonny KEOMISY, Phayvanh SAYALITH, Sandra VALEINA, Maris VIKSNINS, Christiane E AL-HADDAD, Raya H SAAB, Khalifa M ALSAWIDI, Amal M ELBAHI, Dalia KRIVAITIENE, Bekim TATESHI, Hoby Lalaina RANDRIANARISOA, Lea RAOBELA, Gerald MSUKWA, Chinsisi NYIRENDA, Norhafizah HAMZAH, Kok Hoi TEH, Fatoumata SYLLA, Fousseyni TRAORE, Sidi Sidi CHEIKH, Ekhtelbenina ZEIN, Graciela Gonzalez PEREZ, Sanchez Orozco Alma JANETH, Miriam ORTEGA-HERNANDEZ, Marco A RAMIREZ-ORTIZ, Tsengelmaa CHULUUNBAT, Elhassan ABDALLAH, Sarra BENMILOUD, El Kettani ASMAA, Laila HESSISSEN, Argentino A ALMEIDA, Ben LIMBU, Purnima RAJKARNIKAR, Rohit SAIJU, Annette C MOLL, Milo van Hoefen WIJSARD, Ruellyn L COCKCROFT, Yvonne NG, Andrew J DODGSHUN, Patricia CALDERON-SOTELO, Shehu U ABDULLAHI, Sadiq HASSAN, Ali B UMAR, Aminatu A ABDULRAHAMAN, Amina H WALI, Dupe S ADEMOLA-POPOOLA, Adedayo ADIO, Ada E AGHAJI, Ifeoma R EZEGWUI, Adeseye AKINSETE, Kareem O MUSA, Oluyemi FASINA, Affiong IBANGA, Elizabeth D NKANGA, Tajudeen MUSTAPHA, Dahiru RIBADU, Marlies HUMMELEN, Alia AHMAD, Asma MUSHTAQ, Seema QAYYUM, Shabana CHAUDHRY, Zehra FADOO, Irfan JEEVA, Sidra MASUD, Syed A HAMID, Nida ZIA, Shadab HASSAN, Sorath Noorani SIDDIQUI, Teyyeb JANJUA, Muhammad A YAQUB, Hussain A KHAQAN, Quintero D KARINA, Roberto I YEE, Vivekaraj JAIRAJ, Miriam R CANO, Delia D P G FERNANDEZ, Rosdali Y DIAZ CORONADO, Arturo M ZAPATA LOPEZ, Juan L GARCIA, Jimena PONCE, Henry N GARCIA PACHECO, Claudia R PASCUAL MORALES, Vasquez Anchaya Jacqueline KARINA, Fanny F TARRILLO LEIVA, Ana Patricia A ALCASABAS, Gary John V MERCADO, Krzysztof CIESLIK, Wojciech HAUTZ, Anna ROGOWSKA, Guilherme CASTELA, Sonia SILVA, Dong Hyun JO, Jeong Hun KIM, Codruta COMSA, Monica D DRAGOMIR, Vladimir NEROEV, Svetlana SAAKYAN, Vladimir POLYAKOV, Tatiana L USHAKOVA, Vera A YAROVAYA, Andrey A YAROVOY, Tuyisabe THEOPHILE, Al Mesfer SALEH, Azza MAKTABI, Saad A AL-DAHMASH, Hind M ALKATAN, Claude MOREIRA, Paule Aida Ndoye ROTH, Vesna R ILIC, Marina NIKITOVIC, Slobodanka LATINOVIC, BoonLong QUAH, Deborah TAN, Stanislava HEDEROVA, Kristina HUSAKOVA, Alenka Lavric GROZNIK, Manca Tekavcic POMPE, Alan DAVIDSON, Du Bruyn MAGRITHA, Du Plessis JOHANNES, David K STONES, Jennifer A GEEL, Khumo H MYEZO, Mariana KRUGER, Ismail MAYET, Gita NAIDU, Natasha NAIDU, Hamzah MUSTAK, David REYNDERS, Julie WETTER, Alarcon Portabella SILVIA, Nieves MARTIN-BEGUE, Wolley Dod CHARLOTTE, Julia BALAGUER, Honorio BARRANCO, Jaume CATALA-MORA, Maria G CORREA LLANO, Ana FERNANDEZ-TEIJEIRO, Garcia Aldana DAVID, Peralta Calvo JESUS, San Roman Pacheco SONSOLES, D Sanjeeva GUNASEKERA, Moawia M A ELHASSAN, Ahmed A MOHAMEDANI, Charlotta ALL-ERIKSSON, Katarina BARTUMA, Maja Beck POPOVIC, Francis L MUNIER, Chun-Hsiu LIU, Faraja S CHIWANGA, Alice KYARA, Furahini G MNDEME, Mchikirwa S MSINA, Trish A SCANLAN, La-ongsri ATCHANEEYASAKUL, Jassada BUABOONNAM, Wantanee DANGBOON, Penny SINGHA, Suradej HONGENG, Kittisak KULVICHIT, Duangnate ROJANAPORN, Supawan SURUKRATTANASKUL, Nutsuchar WANGTIRAUMNUAY, Atchareeya WIWATWONGWANA, Damrong WIWATWONGWANA, Phanthipha WONGWAI, Manoj K SHARMA, Koffi M GUEDENON, Hedi BOUGUILA, Hatice T ATALAY, Murat HASANREISOGLU, Eda ATASEVEN, Mehmet KANTAR, Ahmet K GUNDUZ, Rejin KEBUDI, Hayyam KIRATLI, Irem KOC, Samuray TUNCER, Emel UNAL, Abubakar KALINAKI, Marchelo MATUA, Keith WADDELL, Anne A MUSIKA, Grace SSALI, Al Harby LAMIS, M Ashwin REDDY, Nicholas J ASTBURY, Covadonga BASCARAN, Richard BOWMAN, Matthew J BURTON, Allen FOSTER, Marcia ZONDERVAN, Mandeep S SAGOO, Nadia BOBROVA, Tetyana SOROCHYNSKA, Lesia LYSYTSIA, Luis CASTILLO, Armin R AFSHAR, Jesse L BERRY, Jonathan W KIM, Jasmeen K RANDHAWA, Elaine BINKLEY, H C BOLDT, Scott A LARSON, Rachel C BRENNAN, Arthika CHANDRAMOHAN, Andrew W STACEY, Timothy W CORSON, David A PLAGER, Jacquelyn M DAVANZO, Arun D SINGH, Hakan DEMIRCI, Connor ERICKSEN, George N MAGRATH, Aaron S GOLD, Timothy G MURRAY, Efren GONZALEZ, Ankoor S SHAH, Eric D HANSEN, M Elizabeth HARTNETT, J William HARBOUR, G Baker HUBBARD, Ogul E UNER, Kelly D LAURENTI, Marilyn B METS, Amy A LEVERANT, Aparna RAMASUBRAMANIAN, Sandra LUNA-FINEMAN, Audra MILLER, Alison H SKALET, Prithvi MRUTHYUNJAYA, Muhammad HASSAN, Scott Cn OLIVER, Carol L SHIELDS, Antonio YAGHY, Erin D STAHL, Matthew W WILSON, Victor M VILLEGAS, Ziyavuddin ISLAMOV, Rustam H USMANOV, Jaime GRAELLS, Livia ROMERO, Chau T M PHAM, Doan L TRANG, Hamoud Hy AL-HUSSAINI, Abdullah Dahan M THAWABA, Kangwa I M MUMA a Mutale NYAYWA
Vydání
LANCET GLOBAL HEALTH, ENGLAND, ELSEVIER SCI LTD, 2022, 2214-109X
Background Retinoblastoma is the most common intraocular cancer worldwide. There is some evidence to suggest that major differences exist in treatment outcomes for children with retinoblastoma from different regions, but these differences have not been assessed on a global scale. We aimed to report 3-year outcomes for children with retinoblastoma globally and to investigate factors associated with survival. Methods We did a prospective cluster-based analysis of treatment-naive patients with retinoblastoma who were diagnosed between Jan 1,2017, and Dec 31,2017, then treated and followed up for 3 years. Patients were recruited from 260 specialised treatment centres worldwide. Data were obtained from participating centres on primary and additional treatments, duration of follow-up, metastasis, eye globe salvage, and survival outcome. We analysed time to death and time to enucleation with Cox regression models. Findings The cohort included 4064 children from 149 countries. The median age at diagnosis was 23.2 months (IQR 11.0-36.5). Extraocular tumour spread (cT4 of the cTNMH classification) at diagnosis was reported in five (0.8%) of 636 children from high-income countries, 55 (5.4%) of 1027 children from upper-middle-income countries, 342 (19. 7%) of 1738 children from lower-middle-income countries, and 196 (42.9%) of 457 children from low-income countries. Enudeation surgery was available for all children and intravenous chemotherapy was available for 4014 (98.8%) of 4064 children. The 3-year survival rate was 99.5% (95% CI 98.8-100.0) for children from high-income countries, 91.2% (89.5-93.0) for children from upper-middle-income countries, 80.3% (78.3-82.3) for children from lower-middle-income countries, and 57.3% (524-63-0) for children from low-income countries. On analysis, independent factors for worse survival were residence in low-income countries compared to high-income countries (hazard ratio 16.67; 95% CI 4.76-50.00), cT4 advanced tumour compared to cT1 (8.98; 4.44-18.18), and older age at diagnosis in children up to 3 years (1.38 per year; 1.23-1.56). For children aged 3-7 years, the mortality risk decreased slightly (p=0.0104 for the change in slope). Interpretation This study, estimated to include approximately half of all new retinoblastoma cases worldwide in 2017, shows profound inequity in survival of children depending on the national income level of their country of residence. In high-income countries, death from retinoblastoma is rare, whereas in low-income countries estimated 3-year survival is just over 50%. Although essential treatments are available in nearly all countries, early diagnosis and treatment in low-income countries are key to improving survival outcomes.
ALIA, Donjeta B, Alketa TANDILI, Luisa PAIVA, Amelia Dc WIME, Guillermo L CHANTADA, Adriana C FANDINO, Mariana SGROI, Ruzanna PAPYAN, Gevorg TAMAMYAN, Jayne E CAMUGLIA, Glen A GOLE, Antony CLARK, Geoffrey C LAM, James E ELDER, John D MCKENZIE, Sandra E STAFFIERI, Michael M JONES, Rebecca MANUDHANE, David SIA, Petra RITTER-SOVINZ, Christoph SCHWAB, Ruhengiz BALAYEVA, Zohora KHAN, Murtuza NURUDDIN, Soma R ROY, Riffat RASHID, Sadia SULTANA, Shawkat A SHAKOOR, Larisa NAUMENKO, Katsiaryna ZHILYAEVA, Paulina BARTOSZEK, Benedicte G BRICHARD, De Potter PATRICK, Amadou I Alfa BIO, Beatriz SALAS, Coleoni Suarez Maria ESTELA, Freddy B MBUMBA, Maria Teresa B C BONANOMI, Carla R. DONATO MACEDO, Nathalia D A K GRIGOROVSKI, Clarissa C D S MATTOSINHO, Luiz F TEIXEIRA, Alexander H OSCAR, Nevyana V VELEVA-KRASTEVA, Gabrielle C BOUDA, Rolande L KABORE, Remezo PHILBERT, Ted Grimbert A EVINA, Henry E NKUMBE, Pius KAMSANG, Okwen M MUYEN, Helen DIMARAS, Ashwin MALLIPATNA, Patrick HAMEL, Rosanne SUPERSTEIN, Katherine E PATON, Caron STRAHLENDORF, Jess Elio Kosh Komba PALET, Harba TYAU-TYAU, Isabel CAVIERES, Juan P LOPEZ, Joaquin OPORTO, Diego OSSANDON, Wensi CHEN, Daoman XIANG, Yi DU, Kaijun LI, Xunda JI, Jing TANG, Cairui LI, Bing XU, Jiang QIAN, Kang XUE, Xiantao SUN, Yi-Zhuo WANG, Yi ZHANG, Si-qi WU, Yishuang XIAO, Huasheng YANG, Huijing YE, Rodrigo A POLANIA, Rokia C BERETE, Line COUITCHERE, Sanja PERIC, Ernesto ALEMANY-RUBIO, Liudmira GONZALEZ-RODRIGUEZ, Rudolf AUTRATA, Tomáš KEPÁK, Pavel POCHOP, Karel SVOJGR, Pernille A GREGERSEN, Steen F URBAK, Margarita M MONTERO, Aleine BUDIONGO, Jenny M YANGA, Theophile B Kabesha AMANI, Robert M LUKAMBA, Marcel N NUMBI, Doris A CALLE JARA, Edwin G VILLACIS CHAFLA, Gissela L SANCHEZ, Sherif ABOUELNAGA, Mahmoud A AFIFI, Alaa M ELHADDAD, Amany M ALI, M. ELZEMBELY, Azza M A SAID, Othman A O ZIKO, Soad L FUENTES-ALABI, Marco A GOENZ, Katrin EERME, Artur KLETT, Diriba F HORDOFA, Aemero A MENGESHA, Sadik T SHERIEF, Tero T KIVELA, Kalle NUMMI, Nathalie CASSOUX, Laurence DESJARDINS, Ghislaine OBONO-OBIANG, Tamar KARDAVA, Zaza KHOTENASHVILI, Nikolaos E BECHRAKIS, Eva M BIEWALD, Sabrina SCHLUETER, Petra KETTELER, Doreen AMANKWAA-FREMPONG, Vera A ESSUMAN, Vivian PAINTSIL, Lorna A RENNER, Amanda ALEJOS, Ana V GIRON, Yvania Alfonso CARRERAS, Ligia D FU, Carlos MALDONADO, Emily S WONG, Jason C YAM, Monika CSOKA, Erika MAKA, Priyanka AGGARWAL, Vineeta GUPTA, Anirban BHADURI, Arpita BHATTACHARYYA, Anirban DAS, Bhavna CHAWLA, Pranab DAS, Sima DAS, Himika GUPTA, Sanjiv GUPTA, Nishant VERMA, Swathi KALIKI, Vikas KHETAN, Puja MAITRA, Amita MAHAJAN, Vikas MENON, Divyansh K C MISHRA, Mahesh Shanmugam PALANIVELU, Rajesh RAMANJULU, Sangeeta S MUDALIAR, Akshay Gopinathan NAIR, Sundaram NATARAJAN, Rachna SETH, Usha SINGH, Sunil BHAT, Gagan DUDEJA, Devjyoti TRIPATHY, Indonesia Marliyanti N R AKIB, Halimah PAGARRA, Primawita O AMIRUDDIN, Mayasari W KUNTORINI, Inggar ARMYTASARI, Eddy SUPRIYADI, I Wayan Eka SUTYAWAN, Putu YULIAWATI, Delfitri LUTFI, Hendrian D SOEBAGJO, Ardizal RAHMAN, Rita S SITORUS, Andi A VICTOR, Edi S TEHUTERU, Widiarti WIDIARTI, Yetty M NENCY, Mohammad FARANOUSH, Azim MEHRVAR, Maryam TASHVIGHI, Ahad SEDAGHAT, Fariba GHASSEMI, Alireza KHODABANDE, Rula A ABDULQADER, Athar A S M AL-SHAHEEN, H. AL ANI MOUROGE, Huda HAYDAR, Safaa A F AL-BADRI, Mazin F AL-JADIRY, Ahmed H SABHAN, Usama AL-JUMAILY, Ali A R M AL-MAFRACHI, Entissar H AL-SHAMMARY, Allawi N Hussein AL-JANABI, Ali O QADIR, Michael CAPRA, Sharon BLUM, Nir GOMEL, Ido Didi FABIAN, Hila GOLDBERG, Noa KAPELUSHNIK, Shiran MADGAR, Victoria VISHNEVSKIA-DAI, Shahar FRENKEL, Jacob PEER, Malka GORFINE, David REFAELI, David M STEINBERG, Yotam LAVY, Helen TOLEDANO, Shani CASPI, De Francesco SONIA, Theodora HADJISTILIANOU, Russo IDA, Paola VALENTE, Edoardo MIDENA, Raffaele PARROZZANI, Kristin E COWAN-LYN, Leon O VAUGHAN, Shigenobu SUZUKI, Mona T MOHAMMAD, Yacoub A YOUSEF, Lyazat MANZHUOVA, Rose ATSIAYA, Ibrahim O MATENDE, Ainura S BEGIMKULOVA, Emil K MAKIMBETOV, Jonny KEOMISY, Phayvanh SAYALITH, Sandra VALEINA, Maris VIKSNINS, Christiane E AL-HADDAD, Raya H SAAB, Khalifa M ALSAWIDI, Amal M ELBAHI, Dalia KRIVAITIENE, Bekim TATESHI, Hoby Lalaina RANDRIANARISOA, Lea RAOBELA, Gerald MSUKWA, Chinsisi NYIRENDA, Norhafizah HAMZAH, Kok Hoi TEH, Fatoumata SYLLA, Fousseyni TRAORE, Sidi Sidi CHEIKH, Ekhtelbenina ZEIN, Graciela Gonzalez PEREZ, Sanchez Orozco Alma JANETH, Miriam ORTEGA-HERNANDEZ, Marco A RAMIREZ-ORTIZ, Tsengelmaa CHULUUNBAT, Elhassan ABDALLAH, Sarra BENMILOUD, El Kettani ASMAA, Laila HESSISSEN, Argentino A ALMEIDA, Ben LIMBU, Purnima RAJKARNIKAR, Rohit SAIJU, Annette C MOLL, Milo van Hoefen WIJSARD, Ruellyn L COCKCROFT, Yvonne NG, Andrew J DODGSHUN, Patricia CALDERON-SOTELO, Shehu U ABDULLAHI, Sadiq HASSAN, Ali B UMAR, Aminatu A ABDULRAHAMAN, Amina H WALI, Dupe S ADEMOLA-POPOOLA, Adedayo ADIO, Ada E AGHAJI, Ifeoma R EZEGWUI, Adeseye AKINSETE, Kareem O MUSA, Oluyemi FASINA, Affiong IBANGA, Elizabeth D NKANGA, Tajudeen MUSTAPHA, Dahiru RIBADU, Marlies HUMMELEN, Alia AHMAD, Asma MUSHTAQ, Seema QAYYUM, Shabana CHAUDHRY, Zehra FADOO, Irfan JEEVA, Sidra MASUD, Syed A HAMID, Nida ZIA, Shadab HASSAN, Sorath Noorani SIDDIQUI, Teyyeb JANJUA, Muhammad A YAQUB, Hussain A KHAQAN, Quintero D KARINA, Roberto I YEE, Vivekaraj JAIRAJ, Miriam R CANO, Delia D P G FERNANDEZ, Rosdali Y DIAZ CORONADO, Arturo M ZAPATA LOPEZ, Juan L GARCIA, Jimena PONCE, Henry N GARCIA PACHECO, Claudia R PASCUAL MORALES, Vasquez Anchaya Jacqueline KARINA, Fanny F TARRILLO LEIVA, Ana Patricia A ALCASABAS, Gary John V MERCADO, Krzysztof CIESLIK, Wojciech HAUTZ, Anna ROGOWSKA, Guilherme CASTELA, Sonia SILVA, Dong Hyun JO, Jeong Hun KIM, Codruta COMSA, Monica D DRAGOMIR, Vladimir NEROEV, Svetlana SAAKYAN, Vladimir POLYAKOV, Tatiana L USHAKOVA, Vera A YAROVAYA, Andrey A YAROVOY, Tuyisabe THEOPHILE, Al Mesfer SALEH, Azza MAKTABI, Saad A AL-DAHMASH, Hind M ALKATAN, Claude MOREIRA, Paule Aida Ndoye ROTH, Vesna R ILIC, Marina NIKITOVIC, Slobodanka LATINOVIC, BoonLong QUAH, Deborah TAN, Stanislava HEDEROVA, Kristina HUSAKOVA, Alenka Lavric GROZNIK, Manca Tekavcic POMPE, Alan DAVIDSON, Du Bruyn MAGRITHA, Du Plessis JOHANNES, David K STONES, Jennifer A GEEL, Khumo H MYEZO, Mariana KRUGER, Ismail MAYET, Gita NAIDU, Natasha NAIDU, Hamzah MUSTAK, David REYNDERS, Julie WETTER, Alarcon Portabella SILVIA, Nieves MARTIN-BEGUE, Wolley Dod CHARLOTTE, Julia BALAGUER, Honorio BARRANCO, Jaume CATALA-MORA, Maria G CORREA LLANO, Ana FERNANDEZ-TEIJEIRO, Garcia Aldana DAVID, Peralta Calvo JESUS, San Roman Pacheco SONSOLES, D Sanjeeva GUNASEKERA, Moawia M A ELHASSAN, Ahmed A MOHAMEDANI, Charlotta ALL-ERIKSSON, Katarina BARTUMA, Maja Beck POPOVIC, Francis L MUNIER, Chun-Hsiu LIU, Faraja S CHIWANGA, Alice KYARA, Furahini G MNDEME, Mchikirwa S MSINA, Trish A SCANLAN, La-ongsri ATCHANEEYASAKUL, Jassada BUABOONNAM, Wantanee DANGBOON, Penny SINGHA, Suradej HONGENG, Kittisak KULVICHIT, Duangnate ROJANAPORN, Supawan SURUKRATTANASKUL, Nutsuchar WANGTIRAUMNUAY, Atchareeya WIWATWONGWANA, Damrong WIWATWONGWANA, Phanthipha WONGWAI, Manoj K SHARMA, Koffi M GUEDENON, Hedi BOUGUILA, Hatice T ATALAY, Murat HASANREISOGLU, Eda ATASEVEN, Mehmet KANTAR, Ahmet K GUNDUZ, Rejin KEBUDI, Hayyam KIRATLI, Irem KOC, Samuray TUNCER, Emel UNAL, Abubakar KALINAKI, Marchelo MATUA, Keith WADDELL, Anne A MUSIKA, Grace SSALI, Al Harby LAMIS, M Ashwin REDDY, Nicholas J ASTBURY, Covadonga BASCARAN, Richard BOWMAN, Matthew J BURTON, Allen FOSTER, Marcia ZONDERVAN, Mandeep S SAGOO, Nadia BOBROVA, Tetyana SOROCHYNSKA, Lesia LYSYTSIA, Luis CASTILLO, Armin R AFSHAR, Jesse L BERRY, Jonathan W KIM, Jasmeen K RANDHAWA, Elaine BINKLEY, H C BOLDT, Scott A LARSON, Rachel C BRENNAN, Arthika CHANDRAMOHAN, Andrew W STACEY, Timothy W CORSON, David A PLAGER, Jacquelyn M DAVANZO, Arun D SINGH, Hakan DEMIRCI, Connor ERICKSEN, George N MAGRATH, Aaron S GOLD, Timothy G MURRAY, Efren GONZALEZ, Ankoor S SHAH, Eric D HANSEN, M Elizabeth HARTNETT, J William HARBOUR, G Baker HUBBARD, Ogul E UNER, Kelly D LAURENTI, Marilyn B METS, Amy A LEVERANT, Aparna RAMASUBRAMANIAN, Sandra LUNA-FINEMAN, Audra MILLER, Alison H SKALET, Prithvi MRUTHYUNJAYA, Muhammad HASSAN, Scott Cn OLIVER, Carol L SHIELDS, Antonio YAGHY, Erin D STAHL, Matthew W WILSON, Victor M VILLEGAS, Ziyavuddin ISLAMOV, Rustam H USMANOV, Jaime GRAELLS, Livia ROMERO, Chau T M PHAM, Doan L TRANG, Hamoud Hy AL-HUSSAINI, Abdullah Dahan M THAWABA, Kangwa I M MUMA a Mutale NYAYWA. The Global Retinoblastoma Outcome Study: a prospective, cluster-based analysis of 4064 patients from 149 countries. LANCET GLOBAL HEALTH. ENGLAND: ELSEVIER SCI LTD, 2022, roč. 10, č. 8, s. "E1128"-"E1140", 13 s. ISSN 2214-109X. Dostupné z: https://dx.doi.org/10.1016/S2214-109X(22)00250-9.
@article{2249860, author = {Alia, Donjeta B and Tandili, Alketa and Paiva, Luisa and Wime, Amelia Dc and Chantada, Guillermo L and Fandino, Adriana C and Sgroi, Mariana and Papyan, Ruzanna and Tamamyan, Gevorg and Camuglia, Jayne E and Gole, Glen A and Clark, Antony and Lam, Geoffrey C and Elder, James E and McKenzie, John D and Staffieri, Sandra E and Jones, Michael M and Manudhane, Rebecca and Sia, David and RitterandSovinz, Petra and Schwab, Christoph and Balayeva, Ruhengiz and Khan, Zohora and Nuruddin, Murtuza and Roy, Soma R and Rashid, Riffat and Sultana, Sadia and Shakoor, Shawkat A and Naumenko, Larisa and Zhilyaeva, Katsiaryna and Bartoszek, Paulina and Brichard, Benedicte G and Patrick, De Potter and Bio, Amadou I Alfa and Salas, Beatriz and Estela, Coleoni Suarez Maria and Mbumba, Freddy B and Bonanomi, Maria Teresa B C and Donato Macedo, Carla R. and Grigorovski, Nathalia D A K and Mattosinho, Clarissa C D S and Teixeira, Luiz F and Oscar, Alexander H and VelevaandKrasteva, Nevyana V and Bouda, Gabrielle C and Kabore, Rolande L and Philbert, Remezo and Evina, Ted Grimbert A and Nkumbe, Henry E and Kamsang, Pius and Muyen, Okwen M and Dimaras, Helen and Mallipatna, Ashwin and Hamel, Patrick and Superstein, Rosanne and Paton, Katherine E and Strahlendorf, Caron and Palet, Jess Elio Kosh Komba and TyauandTyau, Harba and Cavieres, Isabel and Lopez, Juan P and Oporto, Joaquin and Ossandon, Diego and Chen, Wensi and Xiang, Daoman and Du, Yi and Li, Kaijun and Ji, Xunda and Tang, Jing and Li, Cairui and Xu, Bing and Qian, Jiang and Xue, Kang and Sun, Xiantao and Wang, YiandZhuo and Zhang, Yi and Wu, Siandqi and Xiao, Yishuang and Yang, Huasheng and Ye, Huijing and Polania, Rodrigo A and Berete, Rokia C and Couitchere, Line and Peric, Sanja and AlemanyandRubio, Ernesto and GonzalezandRodriguez, Liudmira and Autrata, Rudolf and Kepák, Tomáš and Pochop, Pavel and Svojgr, Karel and Gregersen, Pernille A and Urbak, Steen F and Montero, Margarita M and Budiongo, Aleine and Yanga, Jenny M and Amani, Theophile B Kabesha and Lukamba, Robert M and Numbi, Marcel N and Calle Jara, Doris A and Villacis Chafla, Edwin G and Sanchez, Gissela L and Abouelnaga, Sherif and Afifi, Mahmoud A and Elhaddad, Alaa M and Ali, Amany M and Elzembely, M. and Said, Azza M A and Ziko, Othman A O and FuentesandAlabi, Soad L and Goenz, Marco A and Eerme, Katrin and Klett, Artur and Hordofa, Diriba F and Mengesha, Aemero A and Sherief, Sadik T and Kivela, Tero T and Nummi, Kalle and Cassoux, Nathalie and Desjardins, Laurence and ObonoandObiang, Ghislaine and Kardava, Tamar and Khotenashvili, Zaza and Bechrakis, Nikolaos E and Biewald, Eva M and Schlueter, Sabrina and Ketteler, Petra and AmankwaaandFrempong, Doreen and Essuman, Vera A and Paintsil, Vivian and Renner, Lorna A and Alejos, Amanda and Giron, Ana V and Carreras, Yvania Alfonso and Fu, Ligia D and Maldonado, Carlos and Wong, Emily S and Yam, Jason C and Csoka, Monika and Maka, Erika and Aggarwal, Priyanka and Gupta, Vineeta and Bhaduri, Anirban and Bhattacharyya, Arpita and Das, Anirban and Chawla, Bhavna and Das, Pranab and Das, Sima and Gupta, Himika and Gupta, Sanjiv and Verma, Nishant and Kaliki, Swathi and Khetan, Vikas and Maitra, Puja and Mahajan, Amita and Menon, Vikas and Mishra, Divyansh K C and Palanivelu, Mahesh Shanmugam and Ramanjulu, Rajesh and Mudaliar, Sangeeta S and Nair, Akshay Gopinathan and Natarajan, Sundaram and Seth, Rachna and Singh, Usha and Bhat, Sunil and Dudeja, Gagan and Tripathy, Devjyoti and Akib, Indonesia Marliyanti N R and Pagarra, Halimah and Amiruddin, Primawita O and Kuntorini, Mayasari W and Armytasari, Inggar and Supriyadi, Eddy and Sutyawan, I Wayan Eka and Yuliawati, Putu and Lutfi, Delfitri and Soebagjo, Hendrian D and Rahman, Ardizal and Sitorus, Rita S and Victor, Andi A and Tehuteru, Edi S and Widiarti, Widiarti and Nency, Yetty M and Faranoush, Mohammad and Mehrvar, Azim et al.}, article_location = {ENGLAND}, article_number = {8}, doi = {http://dx.doi.org/10.1016/S2214-109X(22)00250-9}, keywords = {Retinoblastoma}, language = {eng}, issn = {2214-109X}, journal = {LANCET GLOBAL HEALTH}, title = {The Global Retinoblastoma Outcome Study: a prospective, cluster-based analysis of 4064 patients from 149 countries}, url = {https://www.sciencedirect.com/science/article/pii/S2214109X22002509?via%3Dihub}, volume = {10}, year = {2022} }
TY - JOUR ID - 2249860 AU - Alia, Donjeta B - Tandili, Alketa - Paiva, Luisa - Wime, Amelia Dc - Chantada, Guillermo L - Fandino, Adriana C - Sgroi, Mariana - Papyan, Ruzanna - Tamamyan, Gevorg - Camuglia, Jayne E - Gole, Glen A - Clark, Antony - Lam, Geoffrey C - Elder, James E - McKenzie, John D - Staffieri, Sandra E - Jones, Michael M - Manudhane, Rebecca - Sia, David - Ritter-Sovinz, Petra - Schwab, Christoph - Balayeva, Ruhengiz - Khan, Zohora - Nuruddin, Murtuza - Roy, Soma R - Rashid, Riffat - Sultana, Sadia - Shakoor, Shawkat A - Naumenko, Larisa - Zhilyaeva, Katsiaryna - Bartoszek, Paulina - Brichard, Benedicte G - Patrick, De Potter - Bio, Amadou I Alfa - Salas, Beatriz - Estela, Coleoni Suarez Maria - Mbumba, Freddy B - Bonanomi, Maria Teresa B C - Donato Macedo, Carla R. - Grigorovski, Nathalia D A K - Mattosinho, Clarissa C D S - Teixeira, Luiz F - Oscar, Alexander H - Veleva-Krasteva, Nevyana V - Bouda, Gabrielle C - Kabore, Rolande L - Philbert, Remezo - Evina, Ted Grimbert A - Nkumbe, Henry E - Kamsang, Pius - Muyen, Okwen M - Dimaras, Helen - Mallipatna, Ashwin - Hamel, Patrick - Superstein, Rosanne - Paton, Katherine E - Strahlendorf, Caron - Palet, Jess Elio Kosh Komba - Tyau-Tyau, Harba - Cavieres, Isabel - Lopez, Juan P - Oporto, Joaquin - Ossandon, Diego - Chen, Wensi - Xiang, Daoman - Du, Yi - Li, Kaijun - Ji, Xunda - Tang, Jing - Li, Cairui - Xu, Bing - Qian, Jiang - Xue, Kang - Sun, Xiantao - Wang, Yi-Zhuo - Zhang, Yi - Wu, Si-qi - Xiao, Yishuang - Yang, Huasheng - Ye, Huijing - Polania, Rodrigo A - Berete, Rokia C - Couitchere, Line - Peric, Sanja - Alemany-Rubio, Ernesto - Gonzalez-Rodriguez, Liudmira - Autrata, Rudolf - Kepák, Tomáš - Pochop, Pavel - Svojgr, Karel - Gregersen, Pernille A - Urbak, Steen F - Montero, Margarita M - Budiongo, Aleine - Yanga, Jenny M - Amani, Theophile B Kabesha - Lukamba, Robert M - Numbi, Marcel N - Calle Jara, Doris A - Villacis Chafla, Edwin G - Sanchez, Gissela L - Abouelnaga, Sherif - Afifi, Mahmoud A - Elhaddad, Alaa M - Ali, Amany M - Elzembely, M. - Said, Azza M A - Ziko, Othman A O - Fuentes-Alabi, Soad L - Goenz, Marco A - Eerme, Katrin - Klett, Artur - Hordofa, Diriba F - Mengesha, Aemero A - Sherief, Sadik T - Kivela, Tero T - Nummi, Kalle - Cassoux, Nathalie - Desjardins, Laurence - Obono-Obiang, Ghislaine - Kardava, Tamar - Khotenashvili, Zaza - Bechrakis, Nikolaos E - Biewald, Eva M - Schlueter, Sabrina - Ketteler, Petra - Amankwaa-Frempong, Doreen - Essuman, Vera A - Paintsil, Vivian - Renner, Lorna A - Alejos, Amanda - Giron, Ana V - Carreras, Yvania Alfonso - Fu, Ligia D - Maldonado, Carlos - Wong, Emily S - Yam, Jason C - Csoka, Monika - Maka, Erika - Aggarwal, Priyanka - Gupta, Vineeta - Bhaduri, Anirban - Bhattacharyya, Arpita - Das, Anirban - Chawla, Bhavna - Das, Pranab - Das, Sima - Gupta, Himika - Gupta, Sanjiv - Verma, Nishant - Kaliki, Swathi - Khetan, Vikas - Maitra, Puja - Mahajan, Amita - Menon, Vikas - Mishra, Divyansh K C - Palanivelu, Mahesh Shanmugam - Ramanjulu, Rajesh - Mudaliar, Sangeeta S - Nair, Akshay Gopinathan - Natarajan, Sundaram - Seth, Rachna - Singh, Usha - Bhat, Sunil - Dudeja, Gagan - Tripathy, Devjyoti - Akib, Indonesia Marliyanti N R - Pagarra, Halimah - Amiruddin, Primawita O - Kuntorini, Mayasari W - Armytasari, Inggar - Supriyadi, Eddy - Sutyawan, I Wayan Eka - Yuliawati, Putu - Lutfi, Delfitri - Soebagjo, Hendrian D - Rahman, Ardizal - Sitorus, Rita S - Victor, Andi A - Tehuteru, Edi S - Widiarti, Widiarti - Nency, Yetty M - Faranoush, Mohammad - Mehrvar, Azim et al. PY - 2022 TI - The Global Retinoblastoma Outcome Study: a prospective, cluster-based analysis of 4064 patients from 149 countries JF - LANCET GLOBAL HEALTH VL - 10 IS - 8 SP - "E1128"-"E1140" EP - "E1128"-"E1140" PB - ELSEVIER SCI LTD SN - 2214109X KW - Retinoblastoma UR - https://www.sciencedirect.com/science/article/pii/S2214109X22002509?via%3Dihub N2 - Background Retinoblastoma is the most common intraocular cancer worldwide. There is some evidence to suggest that major differences exist in treatment outcomes for children with retinoblastoma from different regions, but these differences have not been assessed on a global scale. We aimed to report 3-year outcomes for children with retinoblastoma globally and to investigate factors associated with survival. Methods We did a prospective cluster-based analysis of treatment-naive patients with retinoblastoma who were diagnosed between Jan 1,2017, and Dec 31,2017, then treated and followed up for 3 years. Patients were recruited from 260 specialised treatment centres worldwide. Data were obtained from participating centres on primary and additional treatments, duration of follow-up, metastasis, eye globe salvage, and survival outcome. We analysed time to death and time to enucleation with Cox regression models. Findings The cohort included 4064 children from 149 countries. The median age at diagnosis was 23.2 months (IQR 11.0-36.5). Extraocular tumour spread (cT4 of the cTNMH classification) at diagnosis was reported in five (0.8%) of 636 children from high-income countries, 55 (5.4%) of 1027 children from upper-middle-income countries, 342 (19. 7%) of 1738 children from lower-middle-income countries, and 196 (42.9%) of 457 children from low-income countries. Enudeation surgery was available for all children and intravenous chemotherapy was available for 4014 (98.8%) of 4064 children. The 3-year survival rate was 99.5% (95% CI 98.8-100.0) for children from high-income countries, 91.2% (89.5-93.0) for children from upper-middle-income countries, 80.3% (78.3-82.3) for children from lower-middle-income countries, and 57.3% (524-63-0) for children from low-income countries. On analysis, independent factors for worse survival were residence in low-income countries compared to high-income countries (hazard ratio 16.67; 95% CI 4.76-50.00), cT4 advanced tumour compared to cT1 (8.98; 4.44-18.18), and older age at diagnosis in children up to 3 years (1.38 per year; 1.23-1.56). For children aged 3-7 years, the mortality risk decreased slightly (p=0.0104 for the change in slope). Interpretation This study, estimated to include approximately half of all new retinoblastoma cases worldwide in 2017, shows profound inequity in survival of children depending on the national income level of their country of residence. In high-income countries, death from retinoblastoma is rare, whereas in low-income countries estimated 3-year survival is just over 50%. Although essential treatments are available in nearly all countries, early diagnosis and treatment in low-income countries are key to improving survival outcomes. ER -
ALIA, Donjeta B, Alketa TANDILI, Luisa PAIVA, Amelia Dc WIME, Guillermo L CHANTADA, Adriana C FANDINO, Mariana SGROI, Ruzanna PAPYAN, Gevorg TAMAMYAN, Jayne E CAMUGLIA, Glen A GOLE, Antony CLARK, Geoffrey C LAM, James E ELDER, John D MCKENZIE, Sandra E STAFFIERI, Michael M JONES, Rebecca MANUDHANE, David SIA, Petra RITTER-SOVINZ, Christoph SCHWAB, Ruhengiz BALAYEVA, Zohora KHAN, Murtuza NURUDDIN, Soma R ROY, Riffat RASHID, Sadia SULTANA, Shawkat A SHAKOOR, Larisa NAUMENKO, Katsiaryna ZHILYAEVA, Paulina BARTOSZEK, Benedicte G BRICHARD, De Potter PATRICK, Amadou I Alfa BIO, Beatriz SALAS, Coleoni Suarez Maria ESTELA, Freddy B MBUMBA, Maria Teresa B C BONANOMI, Carla R. DONATO MACEDO, Nathalia D A K GRIGOROVSKI, Clarissa C D S MATTOSINHO, Luiz F TEIXEIRA, Alexander H OSCAR, Nevyana V VELEVA-KRASTEVA, Gabrielle C BOUDA, Rolande L KABORE, Remezo PHILBERT, Ted Grimbert A EVINA, Henry E NKUMBE, Pius KAMSANG, Okwen M MUYEN, Helen DIMARAS, Ashwin MALLIPATNA, Patrick HAMEL, Rosanne SUPERSTEIN, Katherine E PATON, Caron STRAHLENDORF, Jess Elio Kosh Komba PALET, Harba TYAU-TYAU, Isabel CAVIERES, Juan P LOPEZ, Joaquin OPORTO, Diego OSSANDON, Wensi CHEN, Daoman XIANG, Yi DU, Kaijun LI, Xunda JI, Jing TANG, Cairui LI, Bing XU, Jiang QIAN, Kang XUE, Xiantao SUN, Yi-Zhuo WANG, Yi ZHANG, Si-qi WU, Yishuang XIAO, Huasheng YANG, Huijing YE, Rodrigo A POLANIA, Rokia C BERETE, Line COUITCHERE, Sanja PERIC, Ernesto ALEMANY-RUBIO, Liudmira GONZALEZ-RODRIGUEZ, Rudolf AUTRATA, Tomáš KEPÁK, Pavel POCHOP, Karel SVOJGR, Pernille A GREGERSEN, Steen F URBAK, Margarita M MONTERO, Aleine BUDIONGO, Jenny M YANGA, Theophile B Kabesha AMANI, Robert M LUKAMBA, Marcel N NUMBI, Doris A CALLE JARA, Edwin G VILLACIS CHAFLA, Gissela L SANCHEZ, Sherif ABOUELNAGA, Mahmoud A AFIFI, Alaa M ELHADDAD, Amany M ALI, M. ELZEMBELY, Azza M A SAID, Othman A O ZIKO, Soad L FUENTES-ALABI, Marco A GOENZ, Katrin EERME, Artur KLETT, Diriba F HORDOFA, Aemero A MENGESHA, Sadik T SHERIEF, Tero T KIVELA, Kalle NUMMI, Nathalie CASSOUX, Laurence DESJARDINS, Ghislaine OBONO-OBIANG, Tamar KARDAVA, Zaza KHOTENASHVILI, Nikolaos E BECHRAKIS, Eva M BIEWALD, Sabrina SCHLUETER, Petra KETTELER, Doreen AMANKWAA-FREMPONG, Vera A ESSUMAN, Vivian PAINTSIL, Lorna A RENNER, Amanda ALEJOS, Ana V GIRON, Yvania Alfonso CARRERAS, Ligia D FU, Carlos MALDONADO, Emily S WONG, Jason C YAM, Monika CSOKA, Erika MAKA, Priyanka AGGARWAL, Vineeta GUPTA, Anirban BHADURI, Arpita BHATTACHARYYA, Anirban DAS, Bhavna CHAWLA, Pranab DAS, Sima DAS, Himika GUPTA, Sanjiv GUPTA, Nishant VERMA, Swathi KALIKI, Vikas KHETAN, Puja MAITRA, Amita MAHAJAN, Vikas MENON, Divyansh K C MISHRA, Mahesh Shanmugam PALANIVELU, Rajesh RAMANJULU, Sangeeta S MUDALIAR, Akshay Gopinathan NAIR, Sundaram NATARAJAN, Rachna SETH, Usha SINGH, Sunil BHAT, Gagan DUDEJA, Devjyoti TRIPATHY, Indonesia Marliyanti N R AKIB, Halimah PAGARRA, Primawita O AMIRUDDIN, Mayasari W KUNTORINI, Inggar ARMYTASARI, Eddy SUPRIYADI, I Wayan Eka SUTYAWAN, Putu YULIAWATI, Delfitri LUTFI, Hendrian D SOEBAGJO, Ardizal RAHMAN, Rita S SITORUS, Andi A VICTOR, Edi S TEHUTERU, Widiarti WIDIARTI, Yetty M NENCY, Mohammad FARANOUSH, Azim MEHRVAR, Maryam TASHVIGHI, Ahad SEDAGHAT, Fariba GHASSEMI, Alireza KHODABANDE, Rula A ABDULQADER, Athar A S M AL-SHAHEEN, H. AL ANI MOUROGE, Huda HAYDAR, Safaa A F AL-BADRI, Mazin F AL-JADIRY, Ahmed H SABHAN, Usama AL-JUMAILY, Ali A R M AL-MAFRACHI, Entissar H AL-SHAMMARY, Allawi N Hussein AL-JANABI, Ali O QADIR, Michael CAPRA, Sharon BLUM, Nir GOMEL, Ido Didi FABIAN, Hila GOLDBERG, Noa KAPELUSHNIK, Shiran MADGAR, Victoria VISHNEVSKIA-DAI, Shahar FRENKEL, Jacob PEER, Malka GORFINE, David REFAELI, David M STEINBERG, Yotam LAVY, Helen TOLEDANO, Shani CASPI, De Francesco SONIA, Theodora HADJISTILIANOU, Russo IDA, Paola VALENTE, Edoardo MIDENA, Raffaele PARROZZANI, Kristin E COWAN-LYN, Leon O VAUGHAN, Shigenobu SUZUKI, Mona T MOHAMMAD, Yacoub A YOUSEF, Lyazat MANZHUOVA, Rose ATSIAYA, Ibrahim O MATENDE, Ainura S BEGIMKULOVA, Emil K MAKIMBETOV, Jonny KEOMISY, Phayvanh SAYALITH, Sandra VALEINA, Maris VIKSNINS, Christiane E AL-HADDAD, Raya H SAAB, Khalifa M ALSAWIDI, Amal M ELBAHI, Dalia KRIVAITIENE, Bekim TATESHI, Hoby Lalaina RANDRIANARISOA, Lea RAOBELA, Gerald MSUKWA, Chinsisi NYIRENDA, Norhafizah HAMZAH, Kok Hoi TEH, Fatoumata SYLLA, Fousseyni TRAORE, Sidi Sidi CHEIKH, Ekhtelbenina ZEIN, Graciela Gonzalez PEREZ, Sanchez Orozco Alma JANETH, Miriam ORTEGA-HERNANDEZ, Marco A RAMIREZ-ORTIZ, Tsengelmaa CHULUUNBAT, Elhassan ABDALLAH, Sarra BENMILOUD, El Kettani ASMAA, Laila HESSISSEN, Argentino A ALMEIDA, Ben LIMBU, Purnima RAJKARNIKAR, Rohit SAIJU, Annette C MOLL, Milo van Hoefen WIJSARD, Ruellyn L COCKCROFT, Yvonne NG, Andrew J DODGSHUN, Patricia CALDERON-SOTELO, Shehu U ABDULLAHI, Sadiq HASSAN, Ali B UMAR, Aminatu A ABDULRAHAMAN, Amina H WALI, Dupe S ADEMOLA-POPOOLA, Adedayo ADIO, Ada E AGHAJI, Ifeoma R EZEGWUI, Adeseye AKINSETE, Kareem O MUSA, Oluyemi FASINA, Affiong IBANGA, Elizabeth D NKANGA, Tajudeen MUSTAPHA, Dahiru RIBADU, Marlies HUMMELEN, Alia AHMAD, Asma MUSHTAQ, Seema QAYYUM, Shabana CHAUDHRY, Zehra FADOO, Irfan JEEVA, Sidra MASUD, Syed A HAMID, Nida ZIA, Shadab HASSAN, Sorath Noorani SIDDIQUI, Teyyeb JANJUA, Muhammad A YAQUB, Hussain A KHAQAN, Quintero D KARINA, Roberto I YEE, Vivekaraj JAIRAJ, Miriam R CANO, Delia D P G FERNANDEZ, Rosdali Y DIAZ CORONADO, Arturo M ZAPATA LOPEZ, Juan L GARCIA, Jimena PONCE, Henry N GARCIA PACHECO, Claudia R PASCUAL MORALES, Vasquez Anchaya Jacqueline KARINA, Fanny F TARRILLO LEIVA, Ana Patricia A ALCASABAS, Gary John V MERCADO, Krzysztof CIESLIK, Wojciech HAUTZ, Anna ROGOWSKA, Guilherme CASTELA, Sonia SILVA, Dong Hyun JO, Jeong Hun KIM, Codruta COMSA, Monica D DRAGOMIR, Vladimir NEROEV, Svetlana SAAKYAN, Vladimir POLYAKOV, Tatiana L USHAKOVA, Vera A YAROVAYA, Andrey A YAROVOY, Tuyisabe THEOPHILE, Al Mesfer SALEH, Azza MAKTABI, Saad A AL-DAHMASH, Hind M ALKATAN, Claude MOREIRA, Paule Aida Ndoye ROTH, Vesna R ILIC, Marina NIKITOVIC, Slobodanka LATINOVIC, BoonLong QUAH, Deborah TAN, Stanislava HEDEROVA, Kristina HUSAKOVA, Alenka Lavric GROZNIK, Manca Tekavcic POMPE, Alan DAVIDSON, Du Bruyn MAGRITHA, Du Plessis JOHANNES, David K STONES, Jennifer A GEEL, Khumo H MYEZO, Mariana KRUGER, Ismail MAYET, Gita NAIDU, Natasha NAIDU, Hamzah MUSTAK, David REYNDERS, Julie WETTER, Alarcon Portabella SILVIA, Nieves MARTIN-BEGUE, Wolley Dod CHARLOTTE, Julia BALAGUER, Honorio BARRANCO, Jaume CATALA-MORA, Maria G CORREA LLANO, Ana FERNANDEZ-TEIJEIRO, Garcia Aldana DAVID, Peralta Calvo JESUS, San Roman Pacheco SONSOLES, D Sanjeeva GUNASEKERA, Moawia M A ELHASSAN, Ahmed A MOHAMEDANI, Charlotta ALL-ERIKSSON, Katarina BARTUMA, Maja Beck POPOVIC, Francis L MUNIER, Chun-Hsiu LIU, Faraja S CHIWANGA, Alice KYARA, Furahini G MNDEME, Mchikirwa S MSINA, Trish A SCANLAN, La-ongsri ATCHANEEYASAKUL, Jassada BUABOONNAM, Wantanee DANGBOON, Penny SINGHA, Suradej HONGENG, Kittisak KULVICHIT, Duangnate ROJANAPORN, Supawan SURUKRATTANASKUL, Nutsuchar WANGTIRAUMNUAY, Atchareeya WIWATWONGWANA, Damrong WIWATWONGWANA, Phanthipha WONGWAI, Manoj K SHARMA, Koffi M GUEDENON, Hedi BOUGUILA, Hatice T ATALAY, Murat HASANREISOGLU, Eda ATASEVEN, Mehmet KANTAR, Ahmet K GUNDUZ, Rejin KEBUDI, Hayyam KIRATLI, Irem KOC, Samuray TUNCER, Emel UNAL, Abubakar KALINAKI, Marchelo MATUA, Keith WADDELL, Anne A MUSIKA, Grace SSALI, Al Harby LAMIS, M Ashwin REDDY, Nicholas J ASTBURY, Covadonga BASCARAN, Richard BOWMAN, Matthew J BURTON, Allen FOSTER, Marcia ZONDERVAN, Mandeep S SAGOO, Nadia BOBROVA, Tetyana SOROCHYNSKA, Lesia LYSYTSIA, Luis CASTILLO, Armin R AFSHAR, Jesse L BERRY, Jonathan W KIM, Jasmeen K RANDHAWA, Elaine BINKLEY, H C BOLDT, Scott A LARSON, Rachel C BRENNAN, Arthika CHANDRAMOHAN, Andrew W STACEY, Timothy W CORSON, David A PLAGER, Jacquelyn M DAVANZO, Arun D SINGH, Hakan DEMIRCI, Connor ERICKSEN, George N MAGRATH, Aaron S GOLD, Timothy G MURRAY, Efren GONZALEZ, Ankoor S SHAH, Eric D HANSEN, M Elizabeth HARTNETT, J William HARBOUR, G Baker HUBBARD, Ogul E UNER, Kelly D LAURENTI, Marilyn B METS, Amy A LEVERANT, Aparna RAMASUBRAMANIAN, Sandra LUNA-FINEMAN, Audra MILLER, Alison H SKALET, Prithvi MRUTHYUNJAYA, Muhammad HASSAN, Scott Cn OLIVER, Carol L SHIELDS, Antonio YAGHY, Erin D STAHL, Matthew W WILSON, Victor M VILLEGAS, Ziyavuddin ISLAMOV, Rustam H USMANOV, Jaime GRAELLS, Livia ROMERO, Chau T M PHAM, Doan L TRANG, Hamoud Hy AL-HUSSAINI, Abdullah Dahan M THAWABA, Kangwa I M MUMA a Mutale NYAYWA. The Global Retinoblastoma Outcome Study: a prospective, cluster-based analysis of 4064 patients from 149 countries. \textit{LANCET GLOBAL HEALTH}. ENGLAND: ELSEVIER SCI LTD, 2022, roč.~10, č.~8, s.~''E1128''-''E1140'', 13 s. ISSN~2214-109X. Dostupné z: https://dx.doi.org/10.1016/S2214-109X(22)00250-9.