2022
Reperfusion therapy for ST-elevation myocardial infarction complicated by cardiogenic shock: the European Society of Cardiology EurObservational programme acute cardiovascular care-European association of PCI ST-elevation myocardial infarction registry
ZEYMER, Uwe, Peter LUDMAN, Nicolas DANCHIN, Petr KALA, Cecile LAROCHE et. al.Základní údaje
Originální název
Reperfusion therapy for ST-elevation myocardial infarction complicated by cardiogenic shock: the European Society of Cardiology EurObservational programme acute cardiovascular care-European association of PCI ST-elevation myocardial infarction registry
Autoři
ZEYMER, Uwe (garant), Peter LUDMAN, Nicolas DANCHIN, Petr KALA (203 Česká republika, domácí), Cecile LAROCHE, Chris P. GALE, Aldo P. MAGGIONI, Soraya SIABANI, Masoumeh SADEGHI, Ahmed WAFA, Stanislaw BARTUS a Franz WEIDINGER
Vydání
EUROPEAN HEART JOURNAL-ACUTE CARDIOVASCULAR CARE, OXFORD, OXFORD UNIV PRESS, 2022, 2048-8726
Další údaje
Jazyk
angličtina
Typ výsledku
Článek v odborném periodiku
Obor
30201 Cardiac and Cardiovascular systems
Stát vydavatele
Velká Británie a Severní Irsko
Utajení
není předmětem státního či obchodního tajemství
Odkazy
Impakt faktor
Impact factor: 4.100
Kód RIV
RIV/00216224:14110/22:00128330
Organizační jednotka
Lékařská fakulta
UT WoS
000799468700001
Klíčová slova anglicky
Cardiogenic shock; ST-elevation myocardial infarction; Primary percutaneous coronary intervention; Registry; Reperfusion therapy
Příznaky
Mezinárodní význam, Recenzováno
Změněno: 27. 1. 2023 13:54, Mgr. Tereza Miškechová
Anotace
V originále
Aims To determine the current state of the use of reperfusion and adjunctive therapies and in-hospital outcomes in European Society of Cardiology (ESC) member and affiliated countries for patients with ST-segment elevation myocardial infarction (STEMI) complicated by cardiogenic shock (CS). Methods and results ESC EurObservational Research Programme prospective international cohort study of admissions with STEMI within 24 h of symptom onset (196 centres; 26 ESC member and 3 affiliated countries). Of 11 462 patients enrolled, 448 (3.9%) had CS. Patients with compared to patients without CS, less frequently received primary percutaneous coronary intervention (PCI) (65.5% vs. 72.2%) and fibrinolysis (15.9% vs. 19.0), and more often had no reperfusion therapy (19.0% vs. 8.5%). Mechanical support devices (intraaortic ballon pump 11.2%, extracoporeal membrane oxygenation 0.7%, other 1.1%) were used infrequently in CS. Bleeding definition academic research consortium 2-5 bleeding complications (10.1% vs. 3.0%, P < 0.01) and stroke (4.2% vs. 0.9%, P < 0.01) occurred more frequently in patients with CS. In-hospital mortality was 10-fold higher (35.5% vs. 3.1%) in patients with CS. Mortality in patients with CS in the groups with PCI, fibrinolysis, and no reperfusion therapy were 27.4%, 36.6%, and 62.4%, respectively. Conclusion In this multi-national registry, patients with STEMI complicated by CS less frequently receive reperfusion therapy than patients with STEMI without CS. Early mortality in patients with CS not treated with primary PCI is very high. Therefore, strategies to improve clinical outcome in STEMI with CS are needed.