J 2022

Reperfusion therapy for ST-elevation myocardial infarction complicated by cardiogenic shock: the European Society of Cardiology EurObservational programme acute cardiovascular care-European association of PCI ST-elevation myocardial infarction registry

ZEYMER, Uwe, Peter LUDMAN, Nicolas DANCHIN, Petr KALA, Cecile LAROCHE et. al.

Základní údaje

Originální název

Reperfusion therapy for ST-elevation myocardial infarction complicated by cardiogenic shock: the European Society of Cardiology EurObservational programme acute cardiovascular care-European association of PCI ST-elevation myocardial infarction registry

Autoři

ZEYMER, Uwe (garant), Peter LUDMAN, Nicolas DANCHIN, Petr KALA (203 Česká republika, domácí), Cecile LAROCHE, Chris P. GALE, Aldo P. MAGGIONI, Soraya SIABANI, Masoumeh SADEGHI, Ahmed WAFA, Stanislaw BARTUS a Franz WEIDINGER

Vydání

EUROPEAN HEART JOURNAL-ACUTE CARDIOVASCULAR CARE, OXFORD, OXFORD UNIV PRESS, 2022, 2048-8726

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30201 Cardiac and Cardiovascular systems

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

Impakt faktor

Impact factor: 4.100

Kód RIV

RIV/00216224:14110/22:00128330

Organizační jednotka

Lékařská fakulta

UT WoS

000799468700001

Klíčová slova anglicky

Cardiogenic shock; ST-elevation myocardial infarction; Primary percutaneous coronary intervention; Registry; Reperfusion therapy

Štítky

Příznaky

Mezinárodní význam, Recenzováno
Změněno: 27. 1. 2023 13:54, Mgr. Tereza Miškechová

Anotace

V originále

Aims To determine the current state of the use of reperfusion and adjunctive therapies and in-hospital outcomes in European Society of Cardiology (ESC) member and affiliated countries for patients with ST-segment elevation myocardial infarction (STEMI) complicated by cardiogenic shock (CS). Methods and results ESC EurObservational Research Programme prospective international cohort study of admissions with STEMI within 24 h of symptom onset (196 centres; 26 ESC member and 3 affiliated countries). Of 11 462 patients enrolled, 448 (3.9%) had CS. Patients with compared to patients without CS, less frequently received primary percutaneous coronary intervention (PCI) (65.5% vs. 72.2%) and fibrinolysis (15.9% vs. 19.0), and more often had no reperfusion therapy (19.0% vs. 8.5%). Mechanical support devices (intraaortic ballon pump 11.2%, extracoporeal membrane oxygenation 0.7%, other 1.1%) were used infrequently in CS. Bleeding definition academic research consortium 2-5 bleeding complications (10.1% vs. 3.0%, P < 0.01) and stroke (4.2% vs. 0.9%, P < 0.01) occurred more frequently in patients with CS. In-hospital mortality was 10-fold higher (35.5% vs. 3.1%) in patients with CS. Mortality in patients with CS in the groups with PCI, fibrinolysis, and no reperfusion therapy were 27.4%, 36.6%, and 62.4%, respectively. Conclusion In this multi-national registry, patients with STEMI complicated by CS less frequently receive reperfusion therapy than patients with STEMI without CS. Early mortality in patients with CS not treated with primary PCI is very high. Therefore, strategies to improve clinical outcome in STEMI with CS are needed.