A Brief Physiology of Ion Balance in Mammal Cardiomyocytes

D 2022

A Brief Physiology of Ion Balance in Mammal Cardiomyocytes

NACHTNEBL, Luboš, Petr FILIPENSKÝ, Magda KRECHLEROVÁ, Helena BEDÁŇOVÁ, Alena SEDLÁKOVÁ et. al.

Základní údaje

Originální název

A Brief Physiology of Ion Balance in Mammal Cardiomyocytes

Autoři

NACHTNEBL, Luboš (203 Česká republika, garant, domácí), Petr FILIPENSKÝ (203 Česká republika, domácí), Magda KRECHLEROVÁ (203 Česká republika, domácí), Helena BEDÁŇOVÁ (203 Česká republika, domácí), Alena SEDLÁKOVÁ (203 Česká republika, domácí), Adam VAJČNER (203 Česká republika, domácí), Michal POHANKA (203 Česká republika, domácí) a Petr DOBŠÁK (203 Česká republika, domácí)

Vydání

Brno, Noninvasive methods in cardiology 2022, od s. 99-108, 10 s. 2022

Nakladatel

Masaryk University Press

Další údaje

Jazyk

angličtina

Typ výsledku

Stať ve sborníku

Obor

30201 Cardiac and Cardiovascular systems

Stát vydavatele

Česká republika

Utajení

není předmětem státního či obchodního tajemství

Forma vydání

tištěná verze "print"

Odkazy

URL

Kód RIV

RIV/00216224:14110/22:00128529

Organizační jednotka

Lékařská fakulta

ISBN

978-80-280-0170-4

Klíčová slova anglicky

Ion Balance; Mammal Cardiomyocytes

Štítky

rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 3. 2. 2023 10:18, Mgr. Tereza Miškechová

Anotace

V originále

The muscle cells (cardiomyocytes) that make up all of the heart muscle contract in a repetitive, organized and adapted way in order to ensure the final function of circulatory support. The coordination of the contractile function is ensured thanks to the syncitium structure of the cardiac tissue which allows the propagation of the electrical activity from one cardiac cell to another. This electrical activity translates into an action potential (AP) which represents the result of a cascade of ion transfers (entry of Na+ and Ca++ ions, exit of K+ ions), largely depending on the variations in permeability of the sarcolemma and succeeding from the diastolic potential. The latter, located between -80 and -90 mV, depends on the characteristics of the sarcolemma which, at rest, is almost exclusively permeable to K+ , and on the variations in ionic concentrations (Na+ and K+ ) on either side of this membrane. However, in diastole, the sarcolemma is slightly permeable to Na+ and the concentration gradients are maintained thanks to active transport ensured by an electrogenic ATP-dependent Na+ /K+ membrane pump.

Citovat

NACHTNEBL, Luboš, Petr FILIPENSKÝ, Magda KRECHLEROVÁ, Helena BEDÁŇOVÁ, Alena SEDLÁKOVÁ, Adam VAJČNER, Michal POHANKA a Petr DOBŠÁK. A Brief Physiology of Ion Balance in Mammal Cardiomyocytes. In Cornélissen G., Siegelová J., Dobšák P. Noninvasive methods in cardiology 2022. Brno: Masaryk University Press, 2022, s. 99-108. ISBN 978-80-280-0170-4.

@inproceedings{2252414,
   author = {Nachtnebl, Luboš and Filipenský, Petr and Krechlerová, Magda and Bedáňová, Helena and Sedláková, Alena and Vajčner, Adam and Pohanka, Michal and Dobšák, Petr},
   address = {Brno},
   booktitle = {Noninvasive methods in cardiology 2022},
   editor = {Cornélissen G., Siegelová J., Dobšák P.},
   keywords = {Ion Balance; Mammal Cardiomyocytes},
   howpublished = {tištěná verze "print"},
   language = {eng},
   location = {Brno},
   isbn = {978-80-280-0170-4},
   pages = {99-108},
   publisher = {Masaryk University Press},
   title = {A Brief Physiology of Ion Balance in Mammal Cardiomyocytes},
   url = {https://is.muni.cz/do/med/noninvasive_methods_in_cardiology/Noninvasive_methods_in_cardiology_2022.pdf},
   year = {2022}
}

TY  - JOUR
ID  - 2252414
AU  - Nachtnebl, Luboš - Filipenský, Petr - Krechlerová, Magda - Bedáňová, Helena - Sedláková, Alena - Vajčner, Adam - Pohanka, Michal - Dobšák, Petr
PY  - 2022
TI  - A Brief Physiology of Ion Balance in Mammal Cardiomyocytes
PB  - Masaryk University Press
CY  - Brno
SN  - 9788028001704
KW  - Ion Balance
KW  - Mammal Cardiomyocytes
UR  - https://is.muni.cz/do/med/noninvasive_methods_in_cardiology/Noninvasive_methods_in_cardiology_2022.pdf
N2  - The muscle cells (cardiomyocytes) that make up all of the heart muscle contract in a repetitive, organized and adapted way in order to ensure the final function of circulatory support. The coordination of the contractile function is ensured thanks to the syncitium structure of the cardiac tissue which allows the propagation of the electrical activity from one cardiac cell to another. This electrical activity translates into an action potential (AP) which represents the result of a cascade of ion transfers (entry of Na+ and Ca++ ions, exit of K+ ions), largely depending on the variations in permeability of the sarcolemma and succeeding from the diastolic potential. The latter, located between -80 and -90 mV, depends on the characteristics of the sarcolemma which, at rest, is almost exclusively permeable to K+ , and on the variations in ionic concentrations (Na+ and K+ ) on either side of this membrane. However, in diastole, the sarcolemma is slightly permeable to Na+ and the concentration gradients are maintained thanks to active transport ensured by an electrogenic ATP-dependent Na+ /K+ membrane pump.
ER  -

NACHTNEBL, Luboš, Petr FILIPENSKÝ, Magda KRECHLEROVÁ, Helena BEDÁŇOVÁ, Alena SEDLÁKOVÁ, Adam VAJČNER, Michal POHANKA a Petr DOBŠÁK. A Brief Physiology of Ion Balance in Mammal Cardiomyocytes. In Cornélissen G., Siegelová J., Dobšák P. \textit{Noninvasive methods in cardiology 2022}. Brno: Masaryk University Press, 2022, s.~99-108. ISBN~978-80-280-0170-4.

Podrobný výpis o publikaci