J 2023

Influence of bacteriobilia on postoperative complications in patients with periampullary tumors

SVATOŇ, Roman, Vladimír PROCHÁZKA, Markéta HANSLIANOVÁ a Zdeněk KALA

Základní údaje

Originální název

Influence of bacteriobilia on postoperative complications in patients with periampullary tumors

Autoři

SVATOŇ, Roman (703 Slovensko, garant, domácí), Vladimír PROCHÁZKA (203 Česká republika, domácí), Markéta HANSLIANOVÁ (203 Česká republika, domácí) a Zdeněk KALA (203 Česká republika, domácí)

Vydání

Asian Journal of Surgery, SINGAPORE, ELSEVIER SINGAPORE PTE LTD, 2023, 1015-9584

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30212 Surgery

Stát vydavatele

Singapur

Utajení

není předmětem státního či obchodního tajemství

Odkazy

Impakt faktor

Impact factor: 3.500 v roce 2022

Kód RIV

RIV/00216224:14110/23:00130476

Organizační jednotka

Lékařská fakulta

DOI

UT WoS

000953399000001

Klíčová slova anglicky

Bacteriobilia; Complications; Periampullary tumor

Štítky

Příznaky

Mezinárodní význam, Recenzováno
Změněno: 15. 3. 2024 10:11, Mgr. Tereza Miškechová

Anotace

V originále

Background Periampullary tumours (PAT) may cause obstruction of distal choledochus. The bile stasis is a risk factor for microbial colonisation of bile (bacteriobilia), cholangitis, hepatic insufficiency and coagulopathy. PAT obstruction can be managed surgically or non-operatively - by inserting a biliary drain or stent (BDS). Although BDS allows for adequate bile drainage, liver function restitution and coagulopathy, increased bacteriobilia has been reported and this is associated with an increased incidence of postoperative complications. Methods A monocentric, prospective, comparative study including 100 patients operated with PAT. The effects of bacteriobilia and the presence of a drain in the biliary tract on the development of postoperative complications were evaluated. Results Positive microbial findings in bile were found in 67% of patients. It was 98% in the biliary drain group vs. 36% in non-drained patients (p = 0.0001). In 68% 2 or more different bacterial strains were simultaneously present (p = 0.0001). Patients with a positive microbial finding in bile had more frequent incidence of infectious complications 40.2% (27) vs. 9.1% (3); p = 0.0011. The most frequent infectious complication was wound infection 29.8% (20) vs. 3.03% (1); p = 0.0014. Similarly, a higher incidence of postoperative infectious complications occurred in patients with BDS - 36% (18) vs. 24% (12); p = 0.2752. Conclusion The presence of a drain or stent in the biliary tract significantly increases the microbial colonisation of bile. It is associated with a significant increase in infectious complications, especially infections in the wound.