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@article{2270557,
author = {Balazova, Ludmila and Wolaschka, Tomáš and Rohaľová, Simona and Daneu, Nina and Stahorsky, Martin and Salayova, Aneta and Tkacikova, Ludmila and Eftimova, Jarmila},
article_location = {BASEL},
article_number = {2},
doi = {http://dx.doi.org/10.3390/life13020573},
keywords = {nanoparticles; silver; Agrimonia eupatoria; in situ gel},
language = {eng},
issn = {2075-1729},
journal = {LIFE-BASEL},
title = {In Situ Gel with Silver Nanoparticles Prepared Using Agrimonia eupatoria L. Shows Antibacterial Activity},
url = {https://mdpi-res.com/d_attachment/life/life-13-00573/article_deploy/life-13-00573-v2.pdf?version=1676886955},
volume = {13},
year = {2023}
}
TY - JOUR
ID - 2270557
AU - Balazova, Ludmila - Wolaschka, Tomáš - Rohaľová, Simona - Daneu, Nina - Stahorsky, Martin - Salayova, Aneta - Tkacikova, Ludmila - Eftimova, Jarmila
PY - 2023
TI - In Situ Gel with Silver Nanoparticles Prepared Using Agrimonia eupatoria L. Shows Antibacterial Activity
JF - LIFE-BASEL
VL - 13
IS - 2
SP - 1-20
EP - 1-20
PB - MDPI
SN - 20751729
KW - nanoparticles
KW - silver
KW - Agrimonia eupatoria
KW - in situ gel
UR - https://mdpi-res.com/d_attachment/life/life-13-00573/article_deploy/life-13-00573-v2.pdf?version=1676886955
N2 - Silver nanoparticles (Ag NPs) with antibacterial activity can be prepared in different ways. In our case, we used ecological green synthesis with Agrimonia eupatoria L. The plant extract was used with Ag NPs for the first time to prepare termosensitive in situ gels (ISGs). Such gels are used to heal human or animal skin and mucous membranes, as they can change from a liquid to solid state after application. Ag NPs were characterized with various techniques (FTIR, TEM, size distribution, zeta potential) and their antibacterial activity was tested against Staphylococcus aureus and Escherichia coli. In accordance with the TEM data, we prepared monodispersed spherical Ag NPs with an average size of about 20 nm. Organic active compounds from Agrimonia eupatoria L. were found on their surfaces using FTIR spectroscopy. Surprisingly, only the in situ gel with Ag NPs showed antibacterial activity against Escherichia coli, while Ag NPs alone did not. Ag NPs prepared via green synthesis using plants with medicinal properties and incorporated into ISGs have great potential for wound healing due to the antibacterial activity of Ag NPs and the dermatological activity of organic substances from plants.
ER -
BALAZOVA, Ludmila, Tomáš WOLASCHKA, Simona ROHAĽOVÁ, Nina DANEU, Martin STAHORSKY, Aneta SALAYOVA, Ludmila TKACIKOVA a Jarmila EFTIMOVA. In Situ Gel with Silver Nanoparticles Prepared Using Agrimonia eupatoria L. Shows Antibacterial Activity. \textit{LIFE-BASEL}. BASEL: MDPI, 2023, roč.~13, č.~2, s.~1-20. ISSN~2075-1729. Dostupné z: https://dx.doi.org/10.3390/life13020573.
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