HLINOMAZ, Ota, Z. MOTOVSKA, Petr KALA, M. HROMADKA, J. PRECEK, J. MROZEK, P. CERVINKA, J. KETTNER, J. MATEJKA, A. ZOHOR, J. BIS a Jiří JARKOVSKÝ. All-cause mortality of patients with STEMI, cardiogenic shock and multivessel coronary disease treated with culprit vessel only versus multivessel primary PCI. In ESC Congress 2022 - Barcelona, Spain, 26-29 August 2022. 2022. ISSN 0195-668X.
Další formáty:   BibTeX LaTeX RIS
Základní údaje
Originální název All-cause mortality of patients with STEMI, cardiogenic shock and multivessel coronary disease treated with culprit vessel only versus multivessel primary PCI
Autoři HLINOMAZ, Ota (203 Česká republika, garant, domácí), Z. MOTOVSKA (203 Česká republika), Petr KALA (203 Česká republika, domácí), M. HROMADKA (203 Česká republika), J. PRECEK (203 Česká republika), J. MROZEK (203 Česká republika), P. CERVINKA (203 Česká republika), J. KETTNER (203 Česká republika), J. MATEJKA (203 Česká republika), A. ZOHOR (203 Česká republika), J. BIS (203 Česká republika) a Jiří JARKOVSKÝ (203 Česká republika, domácí).
Vydání ESC Congress 2022 - Barcelona, Spain, 26-29 August 2022, 2022.
Další údaje
Originální jazyk angličtina
Typ výsledku Konferenční abstrakt
Obor 30201 Cardiac and Cardiovascular systems
Stát vydavatele Velká Británie a Severní Irsko
Utajení není předmětem státního či obchodního tajemství
WWW URL
Impakt faktor Impact factor: 39.300
Kód RIV RIV/00216224:14110/22:00129746
Organizační jednotka Lékařská fakulta
ISSN 0195-668X
UT WoS 000894947901282
Klíčová slova anglicky STEMI; cardiogenic shock; multivessel coronary disease; mortality; culprit vessel; multivessel primary PCI
Štítky rivok
Příznaky Mezinárodní význam
Změnil Změnila: Mgr. Tereza Miškechová, učo 341652. Změněno: 24. 4. 2023 15:25.
Anotace
Background Patients with ST elevation myocardial infarction (STEMI) and cardiogenic shock (CS) treated with primary percutaneous coronary intervention (pPCI) have high mortality. A recent trial demonstrated that a culprit vessel-only strategy (CV-pPCI) was superior to immediate multivessel PCI (MV-pPCI) for patients with CS and multivessel coronary artery disease (MVD). Irrespective of it and current guidelines, multivessel PCI is still often used in these patients. Purpose/Methods The study aimed to compare the characteristics and prognosis of patients with CS-STEMI and MVD treated with culprit vessel only pPCI or multivessel PCI during initial procedure. From 2016 to 2020, 23703 primary PCI patients with STEMI were included in the national all-comers registry of cardiovascular interventions. From them, a total of 1213 (5.1%) patients had cardiogenic shock and MVD at admission to the hospital. Initially 921 (75.9%) patients were treated with CV-pPCI and 292 (24.1%) with MV-pPCI. Results CV-pPCI was a preferred strategy to MV-pPCI in men (74.6% vs 25.4%; p<0,001) and women (79.8% vs 20.2%; p<0,001) with CS-STEMI and MVD. Patients with 3-vessel disease and left main disease had higher probability to be treated with MV-pPCI than patients with 2-vessel disease and without left main disease (28.5% vs 18.6%; p<0,001 and 37.7% vs 20.6%; p<0,001).The CV-pPCI and MV-pPCI group patients did not differ in age (68.1±11.2 vs 66.2±11.4 years; p=0.780), previous PCI (16.1% vs 12.0%; p=0.890) and CABG (6.2% vs 4.8%; p=0.376), chronic kidney disease (6.8% vs 8.2%; p=0.426), cardiopulmonary resuscitation (60.4% vs 58.9%; p=0.657) and pulmonary ventilation (66.8% vs 70.5%; p=0.227) at admission, localization of myocardial infarction (anterior 50.8.% vs 58.9%; p=0.671), time to reperfusion (<2 hours 5.2% vs 4.8%; p=0.722) and TIMI flow 0 before PCI (63.1% vs 64.0%; p=0.675). Based on the results of logistic regression analysis, 30-days (odds ratio, 0.99; 95% CI 0.76 to 1.29; p=0.937) and 1-year (odds ratio, 0.91; 95% CI 0.69 to 1.19; p=0.477) all-cause mortality rates were similar in CV-pPCI and MV-pPCI groups. The presence of 3-vessel disease was the strongest adjusted predictor of 30-days (odds ratio, 1.61; 95% CI 1.27 to 2.04; p<0.001) and 1-year (odds ratio, 1.64; 95% CI 1.30 to 2.08; p<0.001) all-cause mortality in patients with STEMI and CS treated with pPCI. Conclusion Immediate multivessel primary PCI is still used in patients with CS-STEMI and MVD in routine clinical practice. We did not find difference in 30-days and 1-year mortality among patients with CS-STEMI and MVD treated either with culprit vessel-only or multivessel primary PCI.
Návaznosti
NV19-02-00086, projekt VaVNázev: Duální protidestičková léčba pacientů s akutním infarktem myokardu v kardiogenním šoku - studie DAPT-SHOCK AMI
Investor: Ministerstvo zdravotnictví ČR, Duální protidestičková léčba pacientů s akutním infarktem myokardu v kardiogenním šoku - studie DAPT-SHOCK AMI
VytisknoutZobrazeno: 25. 7. 2024 00:26