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@proceedings{2277437, author = {Doležalová, Irena and Koriťáková, Eva and Chladek, J. and Jurková, Tereza and Chrastina, Jan and Jurak, P. and Brázdil, Milan}, booktitle = {8th Congress of the European-Academy-of-Neurology (EAN)}, keywords = {EEG; epileptic patients; vagal nerve stimulation}, language = {eng}, title = {Are there differences in EEG between epileptic patients with vagal nerve stimulation (VNS) and healthy controls?}, url = {https://onlinelibrary.wiley.com/doi/epdf/10.1111/ene.15466}, year = {2022} }
TY - CONF ID - 2277437 AU - Doležalová, Irena - Koriťáková, Eva - Chladek, J. - Jurková, Tereza - Chrastina, Jan - Jurak, P. - Brázdil, Milan PY - 2022 TI - Are there differences in EEG between epileptic patients with vagal nerve stimulation (VNS) and healthy controls? KW - EEG KW - epileptic patients KW - vagal nerve stimulation UR - https://onlinelibrary.wiley.com/doi/epdf/10.1111/ene.15466 N2 - Background and aims: The presented work is based on the results of our published work, in which we focused on the VNS efficacy prediction in patients with drug-resistant epilepsy. We found that there are differences in power spectra between VNS responders and non-responders. We asked two more questions. Are there differences between the epileptic patients with VNS and healthy controls? Do the EEG power spectra in healthy controls resemble more responders or non-responders to VNS therapy? Methods: We identified retrospectively EEG recording in epileptic patients with VNS and in healthy controls. The epileptic patients were classified based on the VNS efficacy as responder and non-responders EEG was segmented into several time-intervals (resting-state, eyes-opening 1, resting state, photic stimulation, hyperventilation, eyes opening 2, resting state 3 and resting state) and frequency bands. Subsequently, we established relative EEG power spectra in pre-defined frequency bands and time-intervals. Results: We identified EEG in 56 healthy controls and in 60 epileptic patients with VNS (35 responders, 25 non-responders). When compared healthy controls and epileptic patients, we identified EEG power spectra differences in theta (eyes-opening 1, 2), alpha (eyes-opening 1,2) and beta frequency range (eyes-opening 1). When compared responders to VNS therapy and healthy controls, we found more significant differences than in non-responders. ER -
DOLEŽALOVÁ, Irena, Eva KORIŤÁKOVÁ, J. CHLADEK, Tereza JURKOVÁ, Jan CHRASTINA, P. JURAK a Milan BRÁZDIL. Are there differences in EEG between epileptic patients with vagal nerve stimulation (VNS) and healthy controls? In \textit{8th Congress of the European-Academy-of-Neurology (EAN)}. 2022. ISSN~1351-5101.
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