Predictive factors of multiple sclerosis relapse after the
first demyelinating event: A 5-year follow-up

J 2023

Predictive factors of multiple sclerosis relapse after the first demyelinating event: A 5-year follow-up

KOLČAVA, Jan, Ondřej PELÍŠEK a Eva VLČKOVÁ

Základní údaje

Originální název

Predictive factors of multiple sclerosis relapse after the first demyelinating event: A 5-year follow-up

Autoři

KOLČAVA, Jan (203 Česká republika, domácí), Ondřej PELÍŠEK (203 Česká republika, domácí) a Eva VLČKOVÁ (203 Česká republika, garant, domácí)

Vydání

MULTIPLE SCLEROSIS AND RELATED DISORDERS, OXFORD, ELSEVIER SCI LTD, 2023, 2211-0348

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30210 Clinical neurology

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 4.000 v roce 2022

Kód RIV

RIV/00216224:14110/23:00130653

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1016/j.msard.2023.104566

UT WoS

000940954500001

Klíčová slova anglicky

Clinically isolated syndrome; Magnetic resonance imaging; Multiple sclerosis; Oligoclonal bands; Demyelinating diseases

Štítky

14110221, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 27. 4. 2023 09:44, Mgr. Tereza Miškechová

Anotace

V originále

There is a growing need to discover the characteristics that predict prognostic factors after the first demyelin-ating event. In this study of 141 patients that met the 2017 McDonald criteria, a higher number of oligoclonal bands, cervical spinal cord demyelinating lesions, and sensory involvement were identified as independent predictors of the second demyelinating event during the 5-year follow-up period in patients who experienced the first demyelinating event. The identification of the aforementioned risk variables will make it possible to identify patients who are more likely to exhibit early second demyelinating event, implying more frequent monitoring and consideration of early application of highly effective disease-modifying treatment.

Návaznosti

MUNI/A/1186/2022, interní kód MU

Název: Diagnostika a patofyziologie neuropatické bolesti a dalších symptomů a komorbidit neurologických onemocnění

Investor: Masarykova univerzita, Diagnostika a patofyziologie neuropatické bolesti a dalších symptomů a komorbidit neurologických onemocnění

Citovat

KOLČAVA, Jan, Ondřej PELÍŠEK a Eva VLČKOVÁ. Predictive factors of multiple sclerosis relapse after the first demyelinating event: A 5-year follow-up. MULTIPLE SCLEROSIS AND RELATED DISORDERS. OXFORD: ELSEVIER SCI LTD, 2023, roč. 71, March 2023, s. 1-3. ISSN 2211-0348. Dostupné z: https://dx.doi.org/10.1016/j.msard.2023.104566.

@article{2278168,
   author = {Kolčava, Jan and Pelíšek, Ondřej and Vlčková, Eva},
   article_location = {OXFORD},
   article_number = {March 2023},
   doi = {http://dx.doi.org/10.1016/j.msard.2023.104566},
   keywords = {Clinically isolated syndrome; Magnetic resonance imaging; Multiple sclerosis; Oligoclonal bands; Demyelinating diseases},
   language = {eng},
   issn = {2211-0348},
   journal = {MULTIPLE SCLEROSIS AND RELATED DISORDERS},
   title = {Predictive factors of multiple sclerosis relapse after the first demyelinating event: A 5-year follow-up},
   url = {https://www.sciencedirect.com/science/article/pii/S2211034823000706?via%3Dihub},
   volume = {71},
   year = {2023}
}

TY  - JOUR
ID  - 2278168
AU  - Kolčava, Jan - Pelíšek, Ondřej - Vlčková, Eva
PY  - 2023
TI  - Predictive factors of multiple sclerosis relapse after the first demyelinating event: A 5-year follow-up
JF  - MULTIPLE SCLEROSIS AND RELATED DISORDERS
VL  - 71
IS  - March 2023
SP  - 1-3
EP  - 1-3
PB  - ELSEVIER SCI LTD
SN  - 22110348
KW  - Clinically isolated syndrome
KW  - Magnetic resonance imaging
KW  - Multiple sclerosis
KW  - Oligoclonal bands
KW  - Demyelinating diseases
UR  - https://www.sciencedirect.com/science/article/pii/S2211034823000706?via%3Dihub
N2  - There is a growing need to discover the characteristics that predict prognostic factors after the first demyelin-ating event. In this study of 141 patients that met the 2017 McDonald criteria, a higher number of oligoclonal bands, cervical spinal cord demyelinating lesions, and sensory involvement were identified as independent predictors of the second demyelinating event during the 5-year follow-up period in patients who experienced the first demyelinating event. The identification of the aforementioned risk variables will make it possible to identify patients who are more likely to exhibit early second demyelinating event, implying more frequent monitoring and consideration of early application of highly effective disease-modifying treatment.
ER  -

KOLČAVA, Jan, Ondřej PELÍŠEK a Eva VLČKOVÁ. Predictive factors of multiple sclerosis relapse after the first demyelinating event: A 5-year follow-up. \textit{MULTIPLE SCLEROSIS AND RELATED DISORDERS}. OXFORD: ELSEVIER SCI LTD, 2023, roč.~71, March 2023, s.~1-3. ISSN~2211-0348. Dostupné z: https://dx.doi.org/10.1016/j.msard.2023.104566.

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