Efficacy of the intranasal application of azaperone for
sedation in weaned piglets

J 2023

Efficacy of the intranasal application of azaperone for sedation in weaned piglets

SVOBODA, Martin, Jana BLAHOVA, Jiří JARKOVSKÝ, Adam ZACHARDA, Suzana HAJKOVA et. al.

Základní údaje

Originální název

Efficacy of the intranasal application of azaperone for sedation in weaned piglets

Autoři

SVOBODA, Martin (203 Česká republika, garant), Jana BLAHOVA (203 Česká republika), Jiří JARKOVSKÝ (203 Česká republika, domácí), Adam ZACHARDA (203 Česká republika), Suzana HAJKOVA (203 Česká republika), Jonas VANHARA (203 Česká republika) a Jan VASEK (203 Česká republika)

Vydání

Veterinarni Medicina, Praha, Czech Academy of Agricultural Sciences, 2023, 0375-8427

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

40301 Veterinary science

Stát vydavatele

Česká republika

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 0.700 v roce 2022

Kód RIV

RIV/00216224:14110/23:00131023

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.17221/21/2023-VETMED

UT WoS

000981543900001

Klíčová slova anglicky

behaviour; neuroleptic; pharmacodynamics; swine

Štítky

14119612, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 21. 6. 2023 09:12, Mgr. Tereza Miškechová

Anotace

V originále

The aim of the study was to compare the efficacy of the intranasal and parenteral administration of azaperone in order to achieve pig sedation. A total of 32 weaned piglets divided into 4 groups (8 piglets in each group) were used. Group A was injected intramuscularly (i.m.) with azaperone (Stresnil (R), 40 mg/ml inj.; Elanco Animal Health) at a dose of 2 mg/kg of body weight (b.w.). Group B received a dose of 2 mg/kg b.w. of azaperone intranasally. Group C was given azaperone intranasally at a dose of 4 mg/kg b.w. Group D was given 1 ml of saline intranasally and served as the control group. The response to the defined stimulus (a blunt blow of a metal rod into a metal edge of a pen), the degree of salivation, movement level, body temperature and serum azaperone concentration were included in the trial. We found that in order to induce an adequate level of sedation comparable to the standard method of application, i.e., 2 mg/kg b.w. i.m., the intranasal administration of azaperone at a dose of 4 mg/kg body weight is required.

Citovat

SVOBODA, Martin, Jana BLAHOVA, Jiří JARKOVSKÝ, Adam ZACHARDA, Suzana HAJKOVA, Jonas VANHARA a Jan VASEK. Efficacy of the intranasal application of azaperone for sedation in weaned piglets. Veterinarni Medicina. Praha: Czech Academy of Agricultural Sciences, 2023, roč. 68, č. 4, s. 145-151. ISSN 0375-8427. Dostupné z: https://dx.doi.org/10.17221/21/2023-VETMED.

@article{2292981,
   author = {Svoboda, Martin and Blahova, Jana and Jarkovský, Jiří and Zacharda, Adam and Hajkova, Suzana and Vanhara, Jonas and Vasek, Jan},
   article_location = {Praha},
   article_number = {4},
   doi = {http://dx.doi.org/10.17221/21/2023-VETMED},
   keywords = {behaviour; neuroleptic; pharmacodynamics; swine},
   language = {eng},
   issn = {0375-8427},
   journal = {Veterinarni Medicina},
   title = {Efficacy of the intranasal application of azaperone for sedation in weaned piglets},
   url = {https://vetmed.agriculturejournals.cz/artkey/vet-202304-0002_efficacy-of-the-intranasal-application-of-azaperone-for-sedation-in-weaned-piglets.php},
   volume = {68},
   year = {2023}
}

TY  - JOUR
ID  - 2292981
AU  - Svoboda, Martin - Blahova, Jana - Jarkovský, Jiří - Zacharda, Adam - Hajkova, Suzana - Vanhara, Jonas - Vasek, Jan
PY  - 2023
TI  - Efficacy of the intranasal application of azaperone for sedation in weaned piglets
JF  - Veterinarni Medicina
VL  - 68
IS  - 4
SP  - 145-151
EP  - 145-151
PB  - Czech Academy of Agricultural Sciences
SN  - 03758427
KW  - behaviour
KW  - neuroleptic
KW  - pharmacodynamics
KW  - swine
UR  - https://vetmed.agriculturejournals.cz/artkey/vet-202304-0002_efficacy-of-the-intranasal-application-of-azaperone-for-sedation-in-weaned-piglets.php
N2  - The aim of the study was to compare the efficacy of the intranasal and parenteral administration of azaperone in order to achieve pig sedation. A total of 32 weaned piglets divided into 4 groups (8 piglets in each group) were used. Group A was injected intramuscularly (i.m.) with azaperone (Stresnil (R), 40 mg/ml inj.; Elanco Animal Health) at a dose of 2 mg/kg of body weight (b.w.). Group B received a dose of 2 mg/kg b.w. of azaperone intranasally. Group C was given azaperone intranasally at a dose of 4 mg/kg b.w. Group D was given 1 ml of saline intranasally and served as the control group. The response to the defined stimulus (a blunt blow of a metal rod into a metal edge of a pen), the degree of salivation, movement level, body temperature and serum azaperone concentration were included in the trial. We found that in order to induce an adequate level of sedation comparable to the standard method of application, i.e., 2 mg/kg b.w. i.m., the intranasal administration of azaperone at a dose of 4 mg/kg body weight is required.
ER  -

SVOBODA, Martin, Jana BLAHOVA, Jiří JARKOVSKÝ, Adam ZACHARDA, Suzana HAJKOVA, Jonas VANHARA a Jan VASEK. Efficacy of the intranasal application of azaperone for sedation in weaned piglets. \textit{Veterinarni Medicina}. Praha: Czech Academy of Agricultural Sciences, 2023, roč.~68, č.~4, s.~145-151. ISSN~0375-8427. Dostupné z: https://dx.doi.org/10.17221/21/2023-VETMED.

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