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@proceedings{2293215,
author = {Škovranová, Gabriela and Molčanová, Lenka and Klančnik, Anja and Jug, Blaž and SmoleandMožina, Sonja and Sychrová, Alice},
booktitle = {18th Warsaw International Medical Congress, 21st - 23rd April 2023},
keywords = {antimicrobial activity; eradication; Paulownia tomentosa; quorum-sensing; Staphylococcus aureus},
language = {eng},
title = {Paulownia tomentosa extracts fighting against staphylococcal biofilm formation},
url = {https://wimc.wum.edu.pl/18th-wimc-abstract-book/},
year = {2023}
}
TY - CONF
ID - 2293215
AU - Škovranová, Gabriela - Molčanová, Lenka - Klančnik, Anja - Jug, Blaž - Smole-Možina, Sonja - Sychrová, Alice
PY - 2023
TI - Paulownia tomentosa extracts fighting against staphylococcal biofilm formation
KW - antimicrobial activity
KW - eradication
KW - Paulownia tomentosa
KW - quorum-sensing
KW - Staphylococcus aureus
UR - https://wimc.wum.edu.pl/18th-wimc-abstract-book/
N2 - Staphylococcus aureus is challenging to treat especially if biofilm occurs. Prenylated phenolics provide a significant source of potent antimicrobial agents. Ethanolic extract of Paulownia tomentosa was rich in active compounds, but prenylated flavonoids were dominant in the chloroform fraction. MIC of ethanolic extract, chloroform fraction, and three flavonoids showed significant antimicrobial activity, while lower concentrations prolonged the lag phase. Selected compounds reduced the adhesion of bacteria to the abiotic surface, and also the measurement of bioluminescence showed inhibition of intercellular signaling in bacterial suspension treated with plant formulations.
ER -
ŠKOVRANOVÁ, Gabriela, Lenka MOLČANOVÁ, Anja KLANČNIK, Blaž JUG, Sonja SMOLE-MOŽINA a Alice SYCHROVÁ. Paulownia tomentosa extracts fighting against staphylococcal biofilm formation. In \textit{18th Warsaw International Medical Congress, 21st - 23rd April 2023}. 2023.
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