Plasticity of Dental Cell Types in Development, Regeneration,
and Evolution

J 2023

Plasticity of Dental Cell Types in Development, Regeneration, and Evolution

KŘIVÁNEK, Jan, Marcela BUCHTOVÁ, K. FRIED a I. ADAMEYKO

Základní údaje

Originální název

Plasticity of Dental Cell Types in Development, Regeneration, and Evolution

Autoři

KŘIVÁNEK, Jan (203 Česká republika, domácí), Marcela BUCHTOVÁ (203 Česká republika), K. FRIED a I. ADAMEYKO

Vydání

Journal of Dental Research, THOUSAND OAKS, SAGE PUBLICATIONS INC, 2023, 0022-0345

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10605 Developmental biology

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 7.600 v roce 2022

Kód RIV

RIV/00216224:14110/23:00134154

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1177/00220345231154800

UT WoS

000949948000001

Klíčová slova anglicky

tooth development; stem cell(s); developmental biology; dental informatics; bioinformatics; single-cell RNA-seq; cell differentiation

Štítky

14110517, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 3. 1. 2024 13:01, Mgr. Tereza Miškechová

Anotace

V originále

Recent years have improved our understanding of the plasticity of cell types behind inducing, building, and maintaining different types of teeth. The latest efforts were aided by progress in single-cell transcriptomics, which helped to define not only cell states with mathematical precision but also transitions between them. This includes new aspects of dental epithelial and mesenchymal stem cell niches and beyond. These recent efforts revealed continuous and fluid trajectories connecting cell states during dental development and exposed the natural plasticity of tooth-building progenitors. Such "developmental" plasticity seems to be employed for organizing stem cell niches in adult continuously growing teeth. Furthermore, transitions between mature cell types elicited by trauma might represent a replay of embryonic continuous cell states. Alternatively, they could constitute transitions that evolved de novo, not known from the developmental paradigm. In this review, we discuss and exemplify how dental cell types exhibit plasticity during dynamic processes such as development, self-renewal, repair, and dental replacement. Hypothetically, minor plasticity of cell phenotypes and greater plasticity of transitions between cell subtypes might provide a better response to lifetime challenges, such as damage or dental loss. This plasticity might be additionally harnessed by the evolutionary process during the elaboration of dental cell subtypes in different animal lineages. In turn, the diversification of cell subtypes building teeth brings a diversity of their shape, structural properties, and functions.

Návaznosti

GA23-06160S, projekt VaV

Název: Fluktuace mikroprostředí kmenových buněk jako zdroj tkáňové adaptability ve zdraví a nemoci

Investor: Grantová agentura ČR, Fluktuace mikroprostředí kmenových buněk jako zdroj tkáňové adaptability ve zdraví a nemoci

Citovat

KŘIVÁNEK, Jan, Marcela BUCHTOVÁ, K. FRIED a I. ADAMEYKO. Plasticity of Dental Cell Types in Development, Regeneration, and Evolution. Journal of Dental Research. THOUSAND OAKS: SAGE PUBLICATIONS INC, 2023, roč. 102, č. 6, s. 589-598. ISSN 0022-0345. Dostupné z: https://dx.doi.org/10.1177/00220345231154800.

@article{2294559,
   author = {Křivánek, Jan and Buchtová, Marcela and Fried, K. and Adameyko, I.},
   article_location = {THOUSAND OAKS},
   article_number = {6},
   doi = {http://dx.doi.org/10.1177/00220345231154800},
   keywords = {tooth development; stem cell(s); developmental biology; dental informatics; bioinformatics; single-cell RNA-seq; cell differentiation},
   language = {eng},
   issn = {0022-0345},
   journal = {Journal of Dental Research},
   title = {Plasticity of Dental Cell Types in Development, Regeneration, and Evolution},
   url = {https://journals.sagepub.com/doi/10.1177/00220345231154800},
   volume = {102},
   year = {2023}
}

TY  - JOUR
ID  - 2294559
AU  - Křivánek, Jan - Buchtová, Marcela - Fried, K. - Adameyko, I.
PY  - 2023
TI  - Plasticity of Dental Cell Types in Development, Regeneration, and Evolution
JF  - Journal of Dental Research
VL  - 102
IS  - 6
SP  - 589-598
EP  - 589-598
PB  - SAGE PUBLICATIONS INC
SN  - 00220345
KW  - tooth development
KW  - stem cell(s)
KW  - developmental biology
KW  - dental informatics
KW  - bioinformatics
KW  - single-cell RNA-seq
KW  - cell differentiation
UR  - https://journals.sagepub.com/doi/10.1177/00220345231154800
N2  - Recent years have improved our understanding of the plasticity of cell types behind inducing, building, and maintaining different types of teeth. The latest efforts were aided by progress in single-cell transcriptomics, which helped to define not only cell states with mathematical precision but also transitions between them. This includes new aspects of dental epithelial and mesenchymal stem cell niches and beyond. These recent efforts revealed continuous and fluid trajectories connecting cell states during dental development and exposed the natural plasticity of tooth-building progenitors. Such "developmental" plasticity seems to be employed for organizing stem cell niches in adult continuously growing teeth. Furthermore, transitions between mature cell types elicited by trauma might represent a replay of embryonic continuous cell states. Alternatively, they could constitute transitions that evolved de novo, not known from the developmental paradigm. In this review, we discuss and exemplify how dental cell types exhibit plasticity during dynamic processes such as development, self-renewal, repair, and dental replacement. Hypothetically, minor plasticity of cell phenotypes and greater plasticity of transitions between cell subtypes might provide a better response to lifetime challenges, such as damage or dental loss. This plasticity might be additionally harnessed by the evolutionary process during the elaboration of dental cell subtypes in different animal lineages. In turn, the diversification of cell subtypes building teeth brings a diversity of their shape, structural properties, and functions.
ER  -

KŘIVÁNEK, Jan, Marcela BUCHTOVÁ, K. FRIED a I. ADAMEYKO. Plasticity of Dental Cell Types in Development, Regeneration, and Evolution. \textit{Journal of Dental Research}. THOUSAND OAKS: SAGE PUBLICATIONS INC, 2023, roč.~102, č.~6, s.~589-598. ISSN~0022-0345. Dostupné z: https://dx.doi.org/10.1177/00220345231154800.

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