| VINKLER, Michal, Steven R FIDDAMAN, Martin TESICKY, Emily A CONNOR, Anna E SAVAGE, Tobias L LENZ, Adrian L SMITH, Jim KAUFMAN, Daniel I BOLNICK, Charli S DAVIES, Neira DEDIĆ, Andrew S FLIES, M Mercedes Gomez SAMBLAS, Amberleigh E HENSCHEN, Karel NOVAK, Gemma PALOMAR, Nynke RAVEN, Kalifa SAMAKE, Joel SLADE, Nithya Kuttiyarthu VEETIL, Eleni VOUKALI, Jacob HOGLUND, David S RICHARDSON a Helena WESTERDAHL. Understanding the evolution of immune genes in jawed vertebrates. Journal of Evolutionary Biology. HOBOKEN: Birkhäuser Verlag, 2023, roč. 36, č. 6, s. 847-873. ISSN 1010-061X. Dostupné z: https://dx.doi.org/10.1111/jeb.14181. |
Další formáty:
BibTeX
LaTeX
RIS
@article{2304029,
author = {Vinkler, Michal and Fiddaman, Steven R and Tesicky, Martin and Connor, Emily A and Savage, Anna E and Lenz, Tobias L and Smith, Adrian L and Kaufman, Jim and Bolnick, Daniel I and Davies, Charli S and Dedić, Neira and Flies, Andrew S and Samblas, M Mercedes Gomez and Henschen, Amberleigh E and Novak, Karel and Palomar, Gemma and Raven, Nynke and Samake, Kalifa and Slade, Joel and Veetil, Nithya Kuttiyarthu and Voukali, Eleni and Hoglund, Jacob and Richardson, David S and Westerdahl, Helena},
article_location = {HOBOKEN},
article_number = {6},
doi = {http://dx.doi.org/10.1111/jeb.14181},
keywords = {adaptation; adaptive immunity; evolutionary immunology; genomics; host-parasite interactions; immunogenetics; innate immunity; MHC; molecular evolution; vertebrates},
language = {eng},
issn = {1010-061X},
journal = {Journal of Evolutionary Biology},
title = {Understanding the evolution of immune genes in jawed vertebrates},
url = {https://doi.org/10.1111/jeb.14181},
volume = {36},
year = {2023}
}
TY - JOUR
ID - 2304029
AU - Vinkler, Michal - Fiddaman, Steven R - Tesicky, Martin - Connor, Emily A - Savage, Anna E - Lenz, Tobias L - Smith, Adrian L - Kaufman, Jim - Bolnick, Daniel I - Davies, Charli S - Dedić, Neira - Flies, Andrew S - Samblas, M Mercedes Gomez - Henschen, Amberleigh E - Novak, Karel - Palomar, Gemma - Raven, Nynke - Samake, Kalifa - Slade, Joel - Veetil, Nithya Kuttiyarthu - Voukali, Eleni - Hoglund, Jacob - Richardson, David S - Westerdahl, Helena
PY - 2023
TI - Understanding the evolution of immune genes in jawed vertebrates
JF - Journal of Evolutionary Biology
VL - 36
IS - 6
SP - 847-873
EP - 847-873
PB - Birkhäuser Verlag
SN - 1010061X
KW - adaptation
KW - adaptive immunity
KW - evolutionary immunology
KW - genomics
KW - host-parasite interactions
KW - immunogenetics
KW - innate immunity
KW - MHC
KW - molecular evolution
KW - vertebrates
UR - https://doi.org/10.1111/jeb.14181
N2 - Driven by co-evolution with pathogens, host immunity continuously adapts to optimize defence against pathogens within a given environment. Recent advances in genetics, genomics and transcriptomics have enabled a more detailed investigation into how immunogenetic variation shapes the diversity of immune responses seen across domestic and wild animal species. However, a deeper understanding of the diverse molecular mechanisms that shape immunity within and among species is still needed to gain insight into-and generate evolutionary hypotheses on-the ultimate drivers of immunological differences. Here, we discuss current advances in our understanding of molecular evolution underpinning jawed vertebrate immunity. First, we introduce the immunome concept, a framework for characterizing genes involved in immune defence from a comparative perspective, then we outline how immune genes of interest can be identified. Second, we focus on how different selection modes are observed acting across groups of immune genes and propose hypotheses to explain these differences. We then provide an overview of the approaches used so far to study the evolutionary heterogeneity of immune genes on macro and microevolutionary scales. Finally, we discuss some of the current evidence as to how specific pathogens affect the evolution of different groups of immune genes. This review results from the collective discussion on the current key challenges in evolutionary immunology conducted at the ESEB 2021 Online Satellite Symposium: Molecular evolution of the vertebrate immune system, from the lab to natural populations.
ER -
VINKLER, Michal, Steven R FIDDAMAN, Martin TESICKY, Emily A CONNOR, Anna E SAVAGE, Tobias L LENZ, Adrian L SMITH, Jim KAUFMAN, Daniel I BOLNICK, Charli S DAVIES, Neira DEDI$\backslash$'C, Andrew S FLIES, M Mercedes Gomez SAMBLAS, Amberleigh E HENSCHEN, Karel NOVAK, Gemma PALOMAR, Nynke RAVEN, Kalifa SAMAKE, Joel SLADE, Nithya Kuttiyarthu VEETIL, Eleni VOUKALI, Jacob HOGLUND, David S RICHARDSON a Helena WESTERDAHL. Understanding the evolution of immune genes in jawed vertebrates. \textit{Journal of Evolutionary Biology}. HOBOKEN: Birkhäuser Verlag, 2023, roč.~36, č.~6, s.~847-873. ISSN~1010-061X. Dostupné z: https://dx.doi.org/10.1111/jeb.14181.
|
