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@proceedings{2313178,
author = {Strhársky, Tomáš and Pindjaková, Dominika and Jamrichová, Jaroslava and Lavičková, Juliana and Kadlecová, Veronika and Kleinerová, Kateřina and Kos, Jiří and Goněc, Tomáš and Jampílek, Josef},
booktitle = {51st Conference Synthesis and Analysis of Drugs},
keywords = {cinnamamide; synthesis; antibacterial activity},
language = {eng},
title = {SYNTHESIS OF ANTIBACTERIAL CINNAMAMIDES},
url = {https://sal2023.fpharm.uniba.sk/wp-content/uploads/2023/09/booklet_web.pdf},
year = {2023}
}
TY - CONF
ID - 2313178
AU - Strhársky, Tomáš - Pindjaková, Dominika - Jamrichová, Jaroslava - Lavičková, Juliana - Kadlecová, Veronika - Kleinerová, Kateřina - Kos, Jiří - Goněc, Tomáš - Jampílek, Josef
PY - 2023
TI - SYNTHESIS OF ANTIBACTERIAL CINNAMAMIDES
KW - cinnamamide
KW - synthesis
KW - antibacterial activity
UR - https://sal2023.fpharm.uniba.sk/wp-content/uploads/2023/09/booklet_web.pdf
N2 - Substituted N-phenyl amides of 3,4-dichlorocinnamic acid have been the subject of earlier studies. Some derivatives have shown excellent antimicrobial and antimalarial activity. The newly synthesized compounds that are the subject of this study are direct structural analogues differing in phenyl substitution. 40 derivatives with multiple substitution of both electron-donating and electron-accepting groups were synthesized and characterized, and the antimicrobial activity against Gram-positive bacteria of the genus Staphylococcus was determined. Some derivatives shown excellent activity comparable to the clinically used antibiotics ampicillin and ciprofloxacin.
ER -
STRHÁRSKY, Tomáš, Dominika PINDJAKOVÁ, Jaroslava JAMRICHOVÁ, Juliana LAVIČKOVÁ, Veronika KADLECOVÁ, Kateřina KLEINEROVÁ, Jiří KOS, Tomáš GONĚC a Josef JAMPÍLEK. SYNTHESIS OF ANTIBACTERIAL CINNAMAMIDES. In \textit{51st Conference Synthesis and Analysis of Drugs}. 2023.
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