A Pilot Study on the Functional Stability of Phonation in EEG
Bands After Repetitive Transcranial Magnetic Stimulation in
Parkinson's Disease

J 2023

A Pilot Study on the Functional Stability of Phonation in EEG Bands After Repetitive Transcranial Magnetic Stimulation in Parkinson's Disease

GOMEZ-RODELLAR, Andres, Jiri MEKYSKA, Pedro GOMEZ-VILDA, Luboš BRABENEC, Patrik ŠIMKO et. al.

Základní údaje

Originální název

A Pilot Study on the Functional Stability of Phonation in EEG Bands After Repetitive Transcranial Magnetic Stimulation in Parkinson's Disease

Autoři

GOMEZ-RODELLAR, Andres, Jiri MEKYSKA (203 Česká republika), Pedro GOMEZ-VILDA, Luboš BRABENEC (203 Česká republika, domácí), Patrik ŠIMKO (703 Slovensko, domácí) a Irena REKTOROVÁ (203 Česká republika, garant, domácí)

Vydání

INTERNATIONAL JOURNAL OF NEURAL SYSTEMS, SINGAPORE, WORLD SCIENTIFIC PUBL CO PTE LTD, 2023, 0129-0657

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30210 Clinical neurology

Stát vydavatele

Singapur

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 8.000 v roce 2022

Kód RIV

RIV/00216224:14740/23:00132026

Organizační jednotka

Středoevropský technologický institut

DOI

http://dx.doi.org/10.1142/S0129065723500284

UT WoS

000980189400001

Klíčová slova anglicky

Parkinson's disease; functional quality assessment of phonation; acoustical EEG activity monitoring; repetitive transcranial magnetic stimulation

Štítky

14110127, 14110132, CF MAFIL, podil, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 10. 10. 2024 13:22, Ing. Jana Kuchtová

Anotace

V originále

Parkinson's disease (PD) is a neurodegenerative condition with constantly increasing prevalence rates, affecting strongly life quality in terms of neuromotor and cognitive performance. PD symptoms include voice and speech alterations, known as hypokinetic dysarthria (HD). Unstable phonation is one of the manifestations of HD. Repetitive transcranial magnetic stimulation (rTMS) is a rehabilitative treatment thathas been shown to improve some motor and non-motor symptoms of persons with PD (PwP). This study analyzed the phonation functional behavior of 18 participants (13 males, 5 females) with PD diagnosis before (one pre-stimulus) and after (four post-stimulus) evaluation sessions of rTMS treatment, to assess the extent of changes in their phonation stability. Participants were randomized 1:1 to receive either rTMS or sham stimulation. Voice recordings of a sustained vowel [a:] taken immediately before and after the treatment, and at follow-up evaluation sessions (immediately after, at six, ten, and fourteen weeks after the baseline assessment) were processed by inverse filtering to estimate a biomechanical correlate of vocal fold tension. This estimate was further band-pass filtered into EEG-related frequency bands. Log-likelihood ratios (LLRs) between pre- and post-stimulus amplitude distributions of each frequency band showed significant differences in five cases actively stimulated. Seven cases submitted to the sham protocol did not show relevant improvements in phonation instability. Conversely, four active cases did not show phonation improvements, whereas two sham cases did. The study provides early preliminary insights into the capability of phonation quality assessment by monitoring neuromechanical activity from acoustic signals in frequency bands aligned with EEG ones.

Návaznosti

LX22NPO5107, projekt VaV

Název: Národní ústav pro neurologický výzkum

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Národní ústav pro neurologický výzkum, 5.1 EXCELES

NV16-30805A, projekt VaV

Název: Efekt neinvazivní stimulace mozku na hypokinetickou dysartrii, mikrografii a mozkovou plasticitu u pacientů s Parkinsonovou nemocí

734718, interní kód MU

Název: Novel Network-Based Approaches for Studying Cognitive Dysfunction in Behavioral Neurology (Akronym: CoBeN)

Investor: Evropská unie, Novel Network-Based Approaches for Studying Cognitive Dysfunction in Behavioral Neurology, MSCA Marie Skłodowska-Curie Actions (Excellent Science)

90250, velká výzkumná infrastruktura

Název: Czech-BioImaging III

Citovat

GOMEZ-RODELLAR, Andres, Jiri MEKYSKA, Pedro GOMEZ-VILDA, Luboš BRABENEC, Patrik ŠIMKO a Irena REKTOROVÁ. A Pilot Study on the Functional Stability of Phonation in EEG Bands After Repetitive Transcranial Magnetic Stimulation in Parkinson's Disease. INTERNATIONAL JOURNAL OF NEURAL SYSTEMS. SINGAPORE: WORLD SCIENTIFIC PUBL CO PTE LTD, 2023, roč. 33, č. 06, s. 1-21. ISSN 0129-0657. Dostupné z: https://dx.doi.org/10.1142/S0129065723500284.

@article{2329938,
   author = {GomezandRodellar, Andres and Mekyska, Jiri and GomezandVilda, Pedro and Brabenec, Luboš and Šimko, Patrik and Rektorová, Irena},
   article_location = {SINGAPORE},
   article_number = {06},
   doi = {http://dx.doi.org/10.1142/S0129065723500284},
   keywords = {Parkinson's disease; functional quality assessment of phonation; acoustical EEG activity monitoring; repetitive transcranial magnetic stimulation},
   language = {eng},
   issn = {0129-0657},
   journal = {INTERNATIONAL JOURNAL OF NEURAL SYSTEMS},
   title = {A Pilot Study on the Functional Stability of Phonation in EEG Bands After Repetitive Transcranial Magnetic Stimulation in Parkinson's Disease},
   url = {https://www.worldscientific.com/doi/pdf/10.1142/S0129065723500284?download=true},
   volume = {33},
   year = {2023}
}

TY  - JOUR
ID  - 2329938
AU  - Gomez-Rodellar, Andres - Mekyska, Jiri - Gomez-Vilda, Pedro - Brabenec, Luboš - Šimko, Patrik - Rektorová, Irena
PY  - 2023
TI  - A Pilot Study on the Functional Stability of Phonation in EEG Bands After Repetitive Transcranial Magnetic Stimulation in Parkinson's Disease
JF  - INTERNATIONAL JOURNAL OF NEURAL SYSTEMS
VL  - 33
IS  - 06
SP  - 1-21
EP  - 1-21
PB  - WORLD SCIENTIFIC PUBL CO PTE LTD
SN  - 01290657
KW  - Parkinson's disease
KW  - functional quality assessment of phonation
KW  - acoustical EEG activity monitoring
KW  - repetitive transcranial magnetic stimulation
UR  - https://www.worldscientific.com/doi/pdf/10.1142/S0129065723500284?download=true
N2  - Parkinson's disease (PD) is a neurodegenerative condition with constantly increasing prevalence rates, affecting strongly life quality in terms of neuromotor and cognitive performance. PD symptoms include voice and speech alterations, known as hypokinetic dysarthria (HD). Unstable phonation is one of the manifestations of HD. Repetitive transcranial magnetic stimulation (rTMS) is a rehabilitative treatment thathas been shown to improve some motor and non-motor symptoms of persons with PD (PwP). This study analyzed the phonation functional behavior of 18 participants (13 males, 5 females) with PD diagnosis before (one pre-stimulus) and after (four post-stimulus) evaluation sessions of rTMS treatment, to assess the extent of changes in their phonation stability. Participants were randomized 1:1 to receive either rTMS or sham stimulation. Voice recordings of a sustained vowel [a:] taken immediately before and after the treatment, and at follow-up evaluation sessions (immediately after, at six, ten, and fourteen weeks after the baseline assessment) were processed by inverse filtering to estimate a biomechanical correlate of vocal fold tension. This estimate was further band-pass filtered into EEG-related frequency bands. Log-likelihood ratios (LLRs) between pre- and post-stimulus amplitude distributions of each frequency band showed significant differences in five cases actively stimulated. Seven cases submitted to the sham protocol did not show relevant improvements in phonation instability. Conversely, four active cases did not show phonation improvements, whereas two sham cases did. The study provides early preliminary insights into the capability of phonation quality assessment by monitoring neuromechanical activity from acoustic signals in frequency bands aligned with EEG ones.
ER  -

GOMEZ-RODELLAR, Andres, Jiri MEKYSKA, Pedro GOMEZ-VILDA, Luboš BRABENEC, Patrik ŠIMKO a Irena REKTOROVÁ. A Pilot Study on the Functional Stability of Phonation in EEG Bands After Repetitive Transcranial Magnetic Stimulation in Parkinson's Disease. \textit{INTERNATIONAL JOURNAL OF NEURAL SYSTEMS}. SINGAPORE: WORLD SCIENTIFIC PUBL CO PTE LTD, 2023, roč.~33, č.~06, s.~1-21. ISSN~0129-0657. Dostupné z: https://dx.doi.org/10.1142/S0129065723500284.

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