KELLER, Filip, Helena ANTONI, Petra MINARČÍKOVÁ, Ondřej HRDÝ a Roman GÁL. Mucormycosis in a Severe Trauma Patient Treated with a Combination of Systemic Posaconazole and Topical Amphotericin B—Case Report. Antibiotics. BASEL: MDPI, 2023, roč. 12, č. 10, s. 1-7. ISSN 2079-6382. Dostupné z: https://dx.doi.org/10.3390/antibiotics12101489. |
Další formáty:
BibTeX
LaTeX
RIS
@article{2333257, author = {Keller, Filip and Antoni, Helena and Minarčíková, Petra and Hrdý, Ondřej and Gál, Roman}, article_location = {BASEL}, article_number = {10}, doi = {http://dx.doi.org/10.3390/antibiotics12101489}, keywords = {mucormycosis; posaconazole; amphotericin B; severe trauma; case report}, language = {eng}, issn = {2079-6382}, journal = {Antibiotics}, title = {Mucormycosis in a Severe Trauma Patient Treated with a Combination of Systemic Posaconazole and Topical Amphotericin B—Case Report}, url = {https://www.mdpi.com/2079-6382/12/10/1489}, volume = {12}, year = {2023} }
TY - JOUR ID - 2333257 AU - Keller, Filip - Antoni, Helena - Minarčíková, Petra - Hrdý, Ondřej - Gál, Roman PY - 2023 TI - Mucormycosis in a Severe Trauma Patient Treated with a Combination of Systemic Posaconazole and Topical Amphotericin B—Case Report JF - Antibiotics VL - 12 IS - 10 SP - 1-7 EP - 1-7 PB - MDPI SN - 20796382 KW - mucormycosis KW - posaconazole KW - amphotericin B KW - severe trauma KW - case report UR - https://www.mdpi.com/2079-6382/12/10/1489 N2 - Mucormycosis is an opportunistic infection affecting mainly immunocompromised hosts. Infection in immunocompetent patients is rare, but may occur typically in trauma or burn victims. We report on a previously healthy young man suffering devastating trauma from an agricultural accident with the subsequent development of a multifocal mucormycosis. Diagnosis was achieved by cultures obtained from non-healing wounds, some of them even covered by a macroscopic mold formation. Specific treatment was initiated soon after the preliminary results indicated mucormycosis. Aggressive surgical therapy, with concomitant use of systemic posaconazole and topical amphotericin B in a combination treatment, led to the elimination of the fungal infection. The remaining deep tissue defects were consequently reconstructed by a muscle flap and skin graft autotransplantation with a good overall outcome, which would not have been possible without the complete remission of mucormycosis. This case study presents the successful use of a combination treatment with systemic posaconazole and topical amphotericin B and underlines the importance of timely and aggressive surgical therapy. ER -
KELLER, Filip, Helena ANTONI, Petra MINARČÍKOVÁ, Ondřej HRDÝ a Roman GÁL. Mucormycosis in a Severe Trauma Patient Treated with a Combination of Systemic Posaconazole and Topical Amphotericin B—Case Report. \textit{Antibiotics}. BASEL: MDPI, 2023, roč.~12, č.~10, s.~1-7. ISSN~2079-6382. Dostupné z: https://dx.doi.org/10.3390/antibiotics12101489.
|