| GEORGIOPOULOS, Georgios, Mattia ZAMPIERI, Silvia MOLARO, Anna CHALOUPKA, Alberto AIMO, Barbara BARRA, Leema ROBERTS, Laura MONJE-GARCIA, Colin EVANS, Nabeel SHEIKH, Rachel BASTIAENEN, Michael COOKLIN, Pier-Giorgio MASCI, Gerald CARR-WHITE, Gherardo FINOCCHIARO a Amedeo CHIRIBIRI. Cardiac magnetic resonance in patients with ARVC and family members: the potential role of native T1 mapping. International Journal of Cardiovascular Imaging. Dordrecht: Springer, 2021, roč. 37, č. 6, s. 2037-2047. ISSN 1569-5794. Dostupné z: https://dx.doi.org/10.1007/s10554-021-02166-7. |
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@article{2335877,
author = {Georgiopoulos, Georgios and Zampieri, Mattia and Molaro, Silvia and Chaloupka, Anna and Aimo, Alberto and Barra, Barbara and Roberts, Leema and MonjeandGarcia, Laura and Evans, Colin and Sheikh, Nabeel and Bastiaenen, Rachel and Cooklin, Michael and Masci, PierandGiorgio and CarrandWhite, Gerald and Finocchiaro, Gherardo and Chiribiri, Amedeo},
article_location = {Dordrecht},
article_number = {6},
doi = {http://dx.doi.org/10.1007/s10554-021-02166-7},
keywords = {ARVC; T1 mapping; Late gadolinium enhancement; Diagnosis},
issn = {1569-5794},
journal = {International Journal of Cardiovascular Imaging},
title = {Cardiac magnetic resonance in patients with ARVC and family members: the potential role of native T1 mapping},
volume = {37},
year = {2021}
}
TY - JOUR
ID - 2335877
AU - Georgiopoulos, Georgios - Zampieri, Mattia - Molaro, Silvia - Chaloupka, Anna - Aimo, Alberto - Barra, Barbara - Roberts, Leema - Monje-Garcia, Laura - Evans, Colin - Sheikh, Nabeel - Bastiaenen, Rachel - Cooklin, Michael - Masci, Pier-Giorgio - Carr-White, Gerald - Finocchiaro, Gherardo - Chiribiri, Amedeo
PY - 2021
TI - Cardiac magnetic resonance in patients with ARVC and family members: the potential role of native T1 mapping
JF - International Journal of Cardiovascular Imaging
VL - 37
IS - 6
SP - 2037-2047
EP - 2037-2047
PB - Springer
SN - 15695794
KW - ARVC
KW - T1 mapping
KW - Late gadolinium enhancement
KW - Diagnosis
N2 - Left ventricular (LV) involvement in patients with arrhythmogenic right ventricular cardiomyopathy (ARVC) is not evaluated in the revised Task Force Criteria, possibly leading to underdiagnosis. This study explored the diagnostic role of myocardial native T1 mapping in patients with ARVC and their first-degree relatives. Thirty ARVC patients (47% males, mean age 45 +/- 27 years) and 59 first-degree relatives not meeting diagnostic criteria underwent CMR with native T1 mapping. C MR was abnormal in 26 (87%) patients with ARVC. The right ventricle was affected in isolation in 13 (43%) patients. Prior to T1 mapping assessment, 2 (7%) patients exhibited isolated LV involvement and 11 (36%) patients showed features of biventricular disease. Left ventricular involvement was manifest as detectable LV late gadolinium enhancement (LGE) in 12 out of 13 cases. According to pre-specified inter-ventricular septal (IVS) T1 mapping thresholds, 11 (37%) patients revealed raised native T1 values including 5 out of the 17 patients who would otherwise have been classified as exhibiting a normal LV by conventional imaging parameters. Native septal T1 values were elevated in 22 (37%) of the 59 first-degree relatives included. Biventricular involvement is commonly observed in ARVC; native myocardial T1 values are raised in more than one third of patients, including a significant proportion of cases that would have been otherwise classified as exhibiting a normal LV using conventional CMR techniques. The significance of abnormal T1 values in first-degree relatives at risk will need validation through longitudinal studies.
ER -
GEORGIOPOULOS, Georgios, Mattia ZAMPIERI, Silvia MOLARO, Anna CHALOUPKA, Alberto AIMO, Barbara BARRA, Leema ROBERTS, Laura MONJE-GARCIA, Colin EVANS, Nabeel SHEIKH, Rachel BASTIAENEN, Michael COOKLIN, Pier-Giorgio MASCI, Gerald CARR-WHITE, Gherardo FINOCCHIARO a Amedeo CHIRIBIRI. Cardiac magnetic resonance in patients with ARVC and family members: the potential role of native T1 mapping. \textit{International Journal of Cardiovascular Imaging}. Dordrecht: Springer, 2021, roč.~37, č.~6, s.~2037-2047. ISSN~1569-5794. Dostupné z: https://dx.doi.org/10.1007/s10554-021-02166-7.
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