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@article{2338641,
author = {Križanová, Oľga and Penesova, Adela and Hokynková, Alica and Pokorná, Andrea and Samadian, Amir and Babula, Petr},
article_location = {Hoboken},
article_number = {2},
doi = {http://dx.doi.org/10.1111/iwj.14405},
keywords = {chronic venous insufficiency; compression therapy; therapy; venous leg ulcers; wound coverage},
language = {eng},
issn = {1742-4801},
journal = {International Wound Journal},
title = {Chronic venous insufficiency and venous leg ulcers: Aetiology, on the pathophysiology-based treatment},
url = {https://onlinelibrary.wiley.com/doi/full/10.1111/iwj.14405},
volume = {21},
year = {2024}
}
TY - JOUR
ID - 2338641
AU - Križanová, Oľga - Penesova, Adela - Hokynková, Alica - Pokorná, Andrea - Samadian, Amir - Babula, Petr
PY - 2024
TI - Chronic venous insufficiency and venous leg ulcers: Aetiology, on the pathophysiology-based treatment
JF - International Wound Journal
VL - 21
IS - 2
SP - 1-9
EP - 1-9
PB - Wiley-Blackwell
SN - 17424801
KW - chronic venous insufficiency
KW - compression therapy
KW - therapy
KW - venous leg ulcers
KW - wound coverage
UR - https://onlinelibrary.wiley.com/doi/full/10.1111/iwj.14405
N2 - The chronic venous disease covers a wide spectrum of venous disorders that are characterized by severely impaired blood return that primarily affects veins in the lower extremities. Morphological and functional abnormalities of the venous system led to chronic venous insufficiency (CVI), and present as leg heaviness/achiness, edema, telangiectasia, and varices. The term 'chronic venous insufficiency' (CVI) refers to a disease of greater severity. Venous dysfunction is associated with venous hypertension and is associated with venous reflux due to poorly functioning or incompetent venous valves, which ultimately reduces venous return, leading to a cascade of morphological, physiological, and histologic abnormalities such as blood pooling, hypoxia, inflammation, swelling, skin changes (lipodermatosclerosis), and in severe cases, venous leg ulcers (VLU). This review summarizes recent knowledge about the aetiology, risk factors, and pathophysiology of VLU and compared the possibilities of their treatment.
ER -
KRIŽANOVÁ, Oľga, Adela PENESOVA, Alica HOKYNKOVÁ, Andrea POKORNÁ, Amir SAMADIAN a Petr BABULA. Chronic venous insufficiency and venous leg ulcers: Aetiology, on the pathophysiology-based treatment. \textit{International Wound Journal}. Hoboken: Wiley-Blackwell, 2024, roč.~21, č.~2, s.~1-9. ISSN~1742-4801. Dostupné z: https://dx.doi.org/10.1111/iwj.14405.
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