Brain Areas Predisposing to the Stroke-Related Epilepsy
Development

J 2023

Brain Areas Predisposing to the Stroke-Related Epilepsy Development

WEISS, Viktor, Pavel ŘÍHA, Irena DOLEŽALOVÁ, Martin KOJAN, Vladimír ČERVEŇÁK et. al.

Základní údaje

Originální název

Brain Areas Predisposing to the Stroke-Related Epilepsy Development

Autoři

WEISS, Viktor (203 Česká republika, domácí), Pavel ŘÍHA (203 Česká republika, domácí), Irena DOLEŽALOVÁ (203 Česká republika, domácí), Martin KOJAN (703 Slovensko, domácí), Vladimír ČERVEŇÁK (203 Česká republika, domácí), Julius SIMKO (203 Česká republika), Roman HERZIG (203 Česká republika) a Ivan REKTOR (203 Česká republika, garant, domácí)

Vydání

Acta Neurologica Scandinavica, MALDEN, WILEY-BLACKWELL, 2023, 0001-6314

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30210 Clinical neurology

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 3.500 v roce 2022

Kód RIV

RIV/00216224:14110/23:00134674

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1155/2023/1439121

UT WoS

001057498800001

Klíčová slova anglicky

stroke-related epilepsy; brain; ischemia;

Štítky

14110119, 14110127, podil, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 15. 2. 2024 21:37, Mgr. Eva Dubská

Anotace

V originále

Background. Stroke-related epilepsy (STRE) represents a significant health problem. We focused on identifying brain areas, which involvement in ischemia predisposes a patient to STRE development. Methods. We retrospectively identified a group of patients with STRE consisting of 33 subjects. Subsequently, age-, sex-, and territory-matched controls who underwent stroke but did not develop STRE (control group (CG)) were identified. The CG was composed of 37 patients. The total ischemia volume and distribution of ischemic changes were compared between STRE and CG. We also analyzed multivariate statistics to identify independent variables predisposing to STRE development. Results. The patients with STRE exhibited a bigger volume of ischemia than CG (average volume of ischemia in STRE 60.8 cm3, in CG 42.4 cm3, p=0.029). When comparing STRE and CG, there were differences in the distribution of ischemic changes in the temporal lobe (transverse (Heschl's) temporal gyri, superior temporal gyrus, and middle temporal gyrus) and parietooccipital region (postcentral gyrus, supramarginal gyrus, angular gyrus, parietal operculum, lingual gyrus, and superior occipital gyrus). The involvement of transverse temporal (Heschl's) gyri (p=0.0222, odds ratio 30.0767), age (p=0.0110, odds ratio 1.0745), and SeLECT score (p=0.0480, odds ratio 1.8682) were identified as independent predictors for STRE development. Conclusion. The higher volume of ischemia correlates with a higher risk of STRE development. Some areas, particularly in the temporal and parietal neocortex, predispose the brain to generate epilepsy after the stroke.

Návaznosti

NU21-04-00254, projekt VaV

Název: Detekce zóny počátku záchvatu u multi-lezionální epilepsie s užitím multimodálního neurozobrazování (Akronym: MultiEPI)

Investor: Ministerstvo zdravotnictví ČR, Detekce zóny počátku záchvatu u multi-lezionální epilepsie s užitím multimodálního neurozobrazování, Podprogram 1 - standardní

Citovat

WEISS, Viktor, Pavel ŘÍHA, Irena DOLEŽALOVÁ, Martin KOJAN, Vladimír ČERVEŇÁK, Julius SIMKO, Roman HERZIG a Ivan REKTOR. Brain Areas Predisposing to the Stroke-Related Epilepsy Development. Acta Neurologica Scandinavica. MALDEN: WILEY-BLACKWELL, 2023, roč. 2023, August 2023, s. 1-6. ISSN 0001-6314. Dostupné z: https://dx.doi.org/10.1155/2023/1439121.

@article{2339921,
   author = {Weiss, Viktor and Říha, Pavel and Doležalová, Irena and Kojan, Martin and Červeňák, Vladimír and Simko, Julius and Herzig, Roman and Rektor, Ivan},
   article_location = {MALDEN},
   article_number = {August 2023},
   doi = {http://dx.doi.org/10.1155/2023/1439121},
   keywords = {stroke-related epilepsy; brain; ischemia;},
   language = {eng},
   issn = {0001-6314},
   journal = {Acta Neurologica Scandinavica},
   title = {Brain Areas Predisposing to the Stroke-Related Epilepsy Development},
   url = {https://www.hindawi.com/journals/ans/2023/1439121/},
   volume = {2023},
   year = {2023}
}

TY  - JOUR
ID  - 2339921
AU  - Weiss, Viktor - Říha, Pavel - Doležalová, Irena - Kojan, Martin - Červeňák, Vladimír - Simko, Julius - Herzig, Roman - Rektor, Ivan
PY  - 2023
TI  - Brain Areas Predisposing to the Stroke-Related Epilepsy Development
JF  - Acta Neurologica Scandinavica
VL  - 2023
IS  - August 2023
SP  - 1-6
EP  - 1-6
PB  - WILEY-BLACKWELL
SN  - 00016314
KW  - stroke-related epilepsy
KW  - brain
KW  - ischemia;
UR  - https://www.hindawi.com/journals/ans/2023/1439121/
N2  - Background. Stroke-related epilepsy (STRE) represents a significant health problem. We focused on identifying brain areas, which involvement in ischemia predisposes a patient to STRE development. Methods. We retrospectively identified a group of patients with STRE consisting of 33 subjects. Subsequently, age-, sex-, and territory-matched controls who underwent stroke but did not develop STRE (control group (CG)) were identified. The CG was composed of 37 patients. The total ischemia volume and distribution of ischemic changes were compared between STRE and CG. We also analyzed multivariate statistics to identify independent variables predisposing to STRE development. Results. The patients with STRE exhibited a bigger volume of ischemia than CG (average volume of ischemia in STRE 60.8 cm3, in CG 42.4 cm3, p=0.029). When comparing STRE and CG, there were differences in the distribution of ischemic changes in the temporal lobe (transverse (Heschl's) temporal gyri, superior temporal gyrus, and middle temporal gyrus) and parietooccipital region (postcentral gyrus, supramarginal gyrus, angular gyrus, parietal operculum, lingual gyrus, and superior occipital gyrus). The involvement of transverse temporal (Heschl's) gyri (p=0.0222, odds ratio 30.0767), age (p=0.0110, odds ratio 1.0745), and SeLECT score (p=0.0480, odds ratio 1.8682) were identified as independent predictors for STRE development. Conclusion. The higher volume of ischemia correlates with a higher risk of STRE development. Some areas, particularly in the temporal and parietal neocortex, predispose the brain to generate epilepsy after the stroke.
ER  -

WEISS, Viktor, Pavel ŘÍHA, Irena DOLEŽALOVÁ, Martin KOJAN, Vladimír ČERVEŇÁK, Julius SIMKO, Roman HERZIG a Ivan REKTOR. Brain Areas Predisposing to the Stroke-Related Epilepsy Development. \textit{Acta Neurologica Scandinavica}. MALDEN: WILEY-BLACKWELL, 2023, roč.~2023, August 2023, s.~1-6. ISSN~0001-6314. Dostupné z: https://dx.doi.org/10.1155/2023/1439121.

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