Laser Ablation Inductively Coupled Plasma Mass Spectrometry as
a Powerful Tool for Spatially Resolved Analysis: An Experiment
for Undergraduate Analytical Chemistry Laboratory

J 2023

Laser Ablation Inductively Coupled Plasma Mass Spectrometry as a Powerful Tool for Spatially Resolved Analysis: An Experiment for Undergraduate Analytical Chemistry Laboratory

KUCHYNKA, Michaela, Hana HOLCOVÁ POLANSKÁ, Jaromír GUMULEC, Viktor KANICKÝ, Tomáš VACULOVIČ et. al.

Základní údaje

Originální název

Laser Ablation Inductively Coupled Plasma Mass Spectrometry as a Powerful Tool for Spatially Resolved Analysis: An Experiment for Undergraduate Analytical Chemistry Laboratory

Autoři

KUCHYNKA, Michaela (203 Česká republika, garant, domácí), Hana HOLCOVÁ POLANSKÁ (203 Česká republika, domácí), Jaromír GUMULEC (203 Česká republika, domácí), Viktor KANICKÝ (203 Česká republika, domácí) a Tomáš VACULOVIČ (203 Česká republika, domácí)

Vydání

Journal of Chemical Education, WASHINGTON, American Chemical Society, 2023, 0021-9584

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30104 Pharmacology and pharmacy

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 3.000 v roce 2022

Kód RIV

RIV/00216224:14310/23:00132316

Organizační jednotka

Přírodovědecká fakulta

DOI

http://dx.doi.org/10.1021/acs.jchemed.2c01111

UT WoS

000979469700001

Klíčová slova anglicky

Upper-Division Undergraduate; Analytical Chemistry; Lasers; Mass Spectrometry; Quantitative Analysis

Štítky

14110515, 14110518, podil, rivok, ÚChL

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 18. 3. 2024 16:06, Mgr. Marie Šípková, DiS.

Anotace

V originále

A new experiment using laser ablation with inductively coupled plasma mass spectrometry (LA-ICP-MS) was designed for chemistry undergraduate students. While most analytical methods only provide information on the amount of the analyte, LA-ICP-MS allows extra information on the distribution of the element in the sample. Because it achieves excellent limits of detection (sub mu g center dot g-1) and high spatial resolution (micrometer scale), it is a powerful technique for imaging any sample. A thin section of mouse tissue was used as a model sample to demonstrate these abilities. The student's task was to determine the distribution of the essential elements Zn, Cu, and Pt (Pt introduced into the tumor tissue from the cytostatic drug (cis Pt)) and quantify their amount.

Návaznosti

MUNI/R/1568/2020, interní kód MU

Název: Study the effectiveness of anticancer drugs (Akronym: STEAD)

Investor: Masarykova univerzita, Study the effectiveness of anticancer drugs, CAREER RESTART

Citovat

KUCHYNKA, Michaela, Hana HOLCOVÁ POLANSKÁ, Jaromír GUMULEC, Viktor KANICKÝ a Tomáš VACULOVIČ. Laser Ablation Inductively Coupled Plasma Mass Spectrometry as a Powerful Tool for Spatially Resolved Analysis: An Experiment for Undergraduate Analytical Chemistry Laboratory. Journal of Chemical Education. WASHINGTON: American Chemical Society, 2023, roč. 100, č. 5, s. 1973-1979. ISSN 0021-9584. Dostupné z: https://dx.doi.org/10.1021/acs.jchemed.2c01111.

@article{2341300,
   author = {Kuchynka, Michaela and Holcová Polanská, Hana and Gumulec, Jaromír and Kanický, Viktor and Vaculovič, Tomáš},
   article_location = {WASHINGTON},
   article_number = {5},
   doi = {http://dx.doi.org/10.1021/acs.jchemed.2c01111},
   keywords = {Upper-Division Undergraduate; Analytical Chemistry; Lasers; Mass Spectrometry; Quantitative Analysis},
   language = {eng},
   issn = {0021-9584},
   journal = {Journal of Chemical Education},
   title = {Laser Ablation Inductively Coupled Plasma Mass Spectrometry as a Powerful Tool for Spatially Resolved Analysis: An Experiment for Undergraduate Analytical Chemistry Laboratory},
   url = {https://pubs.acs.org/doi/10.1021/acs.jchemed.2c01111},
   volume = {100},
   year = {2023}
}

TY  - JOUR
ID  - 2341300
AU  - Kuchynka, Michaela - Holcová Polanská, Hana - Gumulec, Jaromír - Kanický, Viktor - Vaculovič, Tomáš
PY  - 2023
TI  - Laser Ablation Inductively Coupled Plasma Mass Spectrometry as a Powerful Tool for Spatially Resolved Analysis: An Experiment for Undergraduate Analytical Chemistry Laboratory
JF  - Journal of Chemical Education
VL  - 100
IS  - 5
SP  - 1973-1979
EP  - 1973-1979
PB  - American Chemical Society
SN  - 00219584
KW  - Upper-Division Undergraduate
KW  - Analytical Chemistry
KW  - Lasers
KW  - Mass Spectrometry
KW  - Quantitative Analysis
UR  - https://pubs.acs.org/doi/10.1021/acs.jchemed.2c01111
N2  - A new experiment using laser ablation with inductively coupled plasma mass spectrometry (LA-ICP-MS) was designed for chemistry undergraduate students. While most analytical methods only provide information on the amount of the analyte, LA-ICP-MS allows extra information on the distribution of the element in the sample. Because it achieves excellent limits of detection (sub mu g center dot g-1) and high spatial resolution (micrometer scale), it is a powerful technique for imaging any sample. A thin section of mouse tissue was used as a model sample to demonstrate these abilities. The student's task was to determine the distribution of the essential elements Zn, Cu, and Pt (Pt introduced into the tumor tissue from the cytostatic drug (cis Pt)) and quantify their amount.
ER  -

KUCHYNKA, Michaela, Hana HOLCOVÁ POLANSKÁ, Jaromír GUMULEC, Viktor KANICKÝ a Tomáš VACULOVIČ. Laser Ablation Inductively Coupled Plasma Mass Spectrometry as a Powerful Tool for Spatially Resolved Analysis: An Experiment for Undergraduate Analytical Chemistry Laboratory. \textit{Journal of Chemical Education}. WASHINGTON: American Chemical Society, 2023, roč.~100, č.~5, s.~1973-1979. ISSN~0021-9584. Dostupné z: https://dx.doi.org/10.1021/acs.jchemed.2c01111.

Podrobný výpis o publikaci