| POULIMENEAS, Dimitrios, Markela KONIORDOU, Dimitra KOUSI, Christina MERAKOU, Ioannis KOPSIDAS, Grammatiki Christina TSOPELA, Christos D ARGYROPOULOS, Sophia C THEMISTOCLEOUS, George SHIAMAKKIDES, Marinos CONSTANTINOU, Alexandra ALEXANDROU, Evgenia NOULA, Andria NEARCHOU, Jon SALMANTON-GARCÍA, Fiona A STEWART, Sarah HERINGER, Kerstin ALBUS, Elena ÁLVAREZ-BARCO, Alan MACKEN, Romina Di MARZO, Catarina LUIS, Paula VALLE-SIMÓN, Helena H ASKLING, Margot HELLEMANS, Orly SPIVAK, Ruth Joanna DAVIS, Anna Maria AZZINI, Imre BARTA, Lenka SOUČKOVÁ, Ligita JANCORIENE, Murat AKOVA, Patrick W G MALLON, Ole F OLESEN, Jesus FRIAS-INIESTA, Pierre van DAMME, Krisztina TÓTH, Miriam COHEN-KANDLI, Rebecca Jane COX, Petr HUSA, Pontus NAUCLÉR, Laura MARQUES, Jordi OCHANDO, Evelina TACCONELLI, Markus ZEITLINGER, Oliver A CORNELY, Zoi Dorothea PANA a Theoklis E ZAOUTIS. The Challenges of Vaccine Trial Participation among Underserved and Hard-to-Reach Communities: An Internal Expert Consultation of the VACCELERATE Consortium. Vaccines. Basel: MDPI, 2023, roč. 11, č. 12, s. 1784-1795. ISSN 2076-393X. Dostupné z: https://dx.doi.org/10.3390/vaccines11121784. |
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@article{2348937,
author = {Poulimeneas, Dimitrios and Koniordou, Markela and Kousi, Dimitra and Merakou, Christina and Kopsidas, Ioannis and Tsopela, Grammatiki Christina and Argyropoulos, Christos D and Themistocleous, Sophia C and Shiamakkides, George and Constantinou, Marinos and Alexandrou, Alexandra and Noula, Evgenia and Nearchou, Andria and SalmantonandGarcía, Jon and Stewart, Fiona A and Heringer, Sarah and Albus, Kerstin and ÁlvarezandBarco, Elena and Macken, Alan and Marzo, Romina Di and Luis, Catarina and ValleandSimón, Paula and Askling, Helena H and Hellemans, Margot and Spivak, Orly and Davis, Ruth Joanna and Azzini, Anna Maria and Barta, Imre and Součková, Lenka and Jancoriene, Ligita and Akova, Murat and Mallon, Patrick W G and Olesen, Ole F and FriasandIniesta, Jesus and Damme, Pierre van and Tóth, Krisztina and CohenandKandli, Miriam and Cox, Rebecca Jane and Husa, Petr and Nauclér, Pontus and Marques, Laura and Ochando, Jordi and Tacconelli, Evelina and Zeitlinger, Markus and Cornely, Oliver A and Pana, Zoi Dorothea and Zaoutis, Theoklis E},
article_location = {Basel},
article_number = {12},
doi = {http://dx.doi.org/10.3390/vaccines11121784},
keywords = {barriers; COVID-19; Europe; pandemic preparedness; SARS-CoV-2; vaccinations; vaccine education; vaccine trials},
language = {eng},
issn = {2076-393X},
journal = {Vaccines},
title = {The Challenges of Vaccine Trial Participation among Underserved and Hard-to-Reach Communities: An Internal Expert Consultation of the VACCELERATE Consortium},
url = {https://www.mdpi.com/2076-393X/11/12/1784},
volume = {11},
year = {2023}
}
TY - JOUR
ID - 2348937
AU - Poulimeneas, Dimitrios - Koniordou, Markela - Kousi, Dimitra - Merakou, Christina - Kopsidas, Ioannis - Tsopela, Grammatiki Christina - Argyropoulos, Christos D - Themistocleous, Sophia C - Shiamakkides, George - Constantinou, Marinos - Alexandrou, Alexandra - Noula, Evgenia - Nearchou, Andria - Salmanton-García, Jon - Stewart, Fiona A - Heringer, Sarah - Albus, Kerstin - Álvarez-Barco, Elena - Macken, Alan - Marzo, Romina Di - Luis, Catarina - Valle-Simón, Paula - Askling, Helena H - Hellemans, Margot - Spivak, Orly - Davis, Ruth Joanna - Azzini, Anna Maria - Barta, Imre - Součková, Lenka - Jancoriene, Ligita - Akova, Murat - Mallon, Patrick W G - Olesen, Ole F - Frias-Iniesta, Jesus - Damme, Pierre van - Tóth, Krisztina - Cohen-Kandli, Miriam - Cox, Rebecca Jane - Husa, Petr - Nauclér, Pontus - Marques, Laura - Ochando, Jordi - Tacconelli, Evelina - Zeitlinger, Markus - Cornely, Oliver A - Pana, Zoi Dorothea - Zaoutis, Theoklis E
PY - 2023
TI - The Challenges of Vaccine Trial Participation among Underserved and Hard-to-Reach Communities: An Internal Expert Consultation of the VACCELERATE Consortium
JF - Vaccines
VL - 11
IS - 12
SP - 1784
EP - 1784
PB - MDPI
SN - 2076393X
KW - barriers
KW - COVID-19
KW - Europe
KW - pandemic preparedness
KW - SARS-CoV-2
KW - vaccinations
KW - vaccine education
KW - vaccine trials
UR - https://www.mdpi.com/2076-393X/11/12/1784
N2 - Underserved and hard-to-reach population groups are under-represented in vaccine trials. Thus, we aimed to identify the challenges of vaccine trial participation of these groups in member countries of the VACCELERATE network. Seventeen National Coordinators (NC), each representing their respective country (15 European countries, Israel, and Turkey), completed an online survey. From 15 eligible groups, those that were more frequently declared underserved/hard-to-reach in vaccine research were ethnic minorities (76.5%), persons experiencing homelessness (70.6%), illegal workers and refugees (64.7%, each). When prioritization for education on vaccine trials was considered, ethnic groups, migrants, and immigrants (5/17, 29.4%) were the groups most frequently identified by the NC as top targets. The most prominent barriers in vaccine trial participation affecting all groups were low levels of health literacy, reluctance to participate in trials due to engagement level, and low levels of trust in vaccines/vaccinations. This study highlighted population groups considered underserved/hard-to-reach in countries contained within the European region, and the respective barriers these groups face when participating in clinical studies. Our findings aid with the design of tailored interventions (within—and across—countries of the European region) and with the development of strategies to overcome major barriers in phase 2 and phase 3 vaccine trial participation.
ER -
POULIMENEAS, Dimitrios, Markela KONIORDOU, Dimitra KOUSI, Christina MERAKOU, Ioannis KOPSIDAS, Grammatiki Christina TSOPELA, Christos D ARGYROPOULOS, Sophia C THEMISTOCLEOUS, George SHIAMAKKIDES, Marinos CONSTANTINOU, Alexandra ALEXANDROU, Evgenia NOULA, Andria NEARCHOU, Jon SALMANTON-GARCÍA, Fiona A STEWART, Sarah HERINGER, Kerstin ALBUS, Elena ÁLVAREZ-BARCO, Alan MACKEN, Romina Di MARZO, Catarina LUIS, Paula VALLE-SIMÓN, Helena H ASKLING, Margot HELLEMANS, Orly SPIVAK, Ruth Joanna DAVIS, Anna Maria AZZINI, Imre BARTA, Lenka SOUČKOVÁ, Ligita JANCORIENE, Murat AKOVA, Patrick W G MALLON, Ole F OLESEN, Jesus FRIAS-INIESTA, Pierre van DAMME, Krisztina TÓTH, Miriam COHEN-KANDLI, Rebecca Jane COX, Petr HUSA, Pontus NAUCLÉR, Laura MARQUES, Jordi OCHANDO, Evelina TACCONELLI, Markus ZEITLINGER, Oliver A CORNELY, Zoi Dorothea PANA a Theoklis E ZAOUTIS. The Challenges of Vaccine Trial Participation among Underserved and Hard-to-Reach Communities: An Internal Expert Consultation of the VACCELERATE Consortium. \textit{Vaccines}. Basel: MDPI, 2023, roč.~11, č.~12, s.~1784-1795. ISSN~2076-393X. Dostupné z: https://dx.doi.org/10.3390/vaccines11121784.
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