A complex role of Arabidopsis CDKD;3 in meiotic progression and
cytokinesis

J 2023

A complex role of Arabidopsis CDKD;3 in meiotic progression and cytokinesis

TANASA, Sorin, Neha SHUKLA, Albert CAIRO CALZADA, Sri Ranjani GANJI, Pavlína MIKULKOVÁ et. al.

Základní údaje

Originální název

A complex role of Arabidopsis CDKD;3 in meiotic progression and cytokinesis

Autoři

TANASA, Sorin (642 Rumunsko, domácí), Neha SHUKLA (356 Indie, domácí), Albert CAIRO CALZADA (724 Španělsko, domácí), Sri Ranjani GANJI (356 Indie, domácí), Pavlína MIKULKOVÁ (203 Česká republika, domácí), Soňa VALUCHOVÁ (703 Slovensko, domácí), Vivek Kumar RAXWAL (356 Indie, domácí), Claudio CAPITAO, Arp SCHNITTGER, Zbyněk ZDRÁHAL (203 Česká republika, domácí) a Karel ŘÍHA (203 Česká republika, garant, domácí)

Vydání

Plant Direct, Wiley, 2023, 2475-4455

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10611 Plant sciences, botany

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 3.000 v roce 2022

Kód RIV

RIV/00216224:14740/23:00132765

Organizační jednotka

Středoevropský technologický institut

DOI

http://dx.doi.org/10.1002/pld3.477

UT WoS

000943734000001

Klíčová slova anglicky

Arabidopsis thaliana; cell cycle; cyclin dependent kinase; cytokinesis; meiosis

Štítky

CF CELLIM, CF PLANT, CF PROT, REMAP, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 10. 10. 2024 15:20, Ing. Martina Blahová

Anotace

V originále

Meiosis is a specialized cell division that halves the number of chromosomes in two consecutive rounds of chromosome segregation. In angiosperm plants is meiosis followed by mitotic divisions to form rudimentary haploid gametophytes. In Arabidopsis, termination of meiosis and transition to gametophytic development are governed by TDM1 and SMG7 that mediate inhibition of translation. Mutants deficient in this mechanism do not form tetrads but instead undergo multiple cycles of aberrant nuclear divisions that are likely caused by the failure to downregulate cyclin dependent kinases during meiotic exit. A suppressor screen to identify genes that contribute to meiotic exit uncovered a mutation in cyclin-dependent kinase D;3 (CDKD;3) that alleviates meiotic defects in smg7 deficient plants. The CDKD;3 deficiency prevents aberrant meiotic divisions observed in smg7 mutants or delays their onset after initiation of cytokinesis, which permits formation of functional microspores. Although CDKD;3 acts as an activator of cyclin-dependent kinase A;1 (CDKA;1), the main cyclin dependent kinase that regulates meiosis, cdkd;3 mutation appears to promote meiotic exit independently of CDKA;1. Furthermore, analysis of CDKD;3 interactome revealed enrichment for proteins implicated in cytokinesis, suggesting a more complex function of CDKD;3 in cell cycle regulation.

Návaznosti

EF15_003/0000479, projekt VaV

Název: Regulace rostlinné meiózy

GC21-25163J, projekt VaV

Název: Funkce a dynamika telomér v rostlinné meióze

Investor: Grantová agentura ČR, Funkce a dynamika telomér v rostlinné meióze

LM2018127, projekt VaV

Název: Česká infrastruktura pro integrativní strukturní biologii (Akronym: CIISB)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Czech Infrastructure for Integrative Structural Biology

90127, velká výzkumná infrastruktura

Název: CIISB II

90129, velká výzkumná infrastruktura

Název: Czech-BioImaging II

Citovat

TANASA, Sorin, Neha SHUKLA, Albert CAIRO CALZADA, Sri Ranjani GANJI, Pavlína MIKULKOVÁ, Soňa VALUCHOVÁ, Vivek Kumar RAXWAL, Claudio CAPITAO, Arp SCHNITTGER, Zbyněk ZDRÁHAL a Karel ŘÍHA. A complex role of Arabidopsis CDKD;3 in meiotic progression and cytokinesis. Plant Direct. Wiley, 2023, roč. 7, č. 3, s. 1-16. ISSN 2475-4455. Dostupné z: https://dx.doi.org/10.1002/pld3.477.

@article{2355903,
   author = {Tanasa, Sorin and Shukla, Neha and Cairo Calzada, Albert and Ganji, Sri Ranjani and Mikulková, Pavlína and Valuchová, Soňa and Raxwal, Vivek Kumar and Capitao, Claudio and Schnittger, Arp and Zdráhal, Zbyněk and Říha, Karel},
   article_number = {3},
   doi = {http://dx.doi.org/10.1002/pld3.477},
   keywords = {Arabidopsis thaliana; cell cycle; cyclin dependent kinase; cytokinesis; meiosis},
   language = {eng},
   issn = {2475-4455},
   journal = {Plant Direct},
   title = {A complex role of Arabidopsis CDKD;3 in meiotic progression and cytokinesis},
   url = {https://doi.org/10.1002/pld3.477},
   volume = {7},
   year = {2023}
}

TY  - JOUR
ID  - 2355903
AU  - Tanasa, Sorin - Shukla, Neha - Cairo Calzada, Albert - Ganji, Sri Ranjani - Mikulková, Pavlína - Valuchová, Soňa - Raxwal, Vivek Kumar - Capitao, Claudio - Schnittger, Arp - Zdráhal, Zbyněk - Říha, Karel
PY  - 2023
TI  - A complex role of Arabidopsis CDKD;3 in meiotic progression and cytokinesis
JF  - Plant Direct
VL  - 7
IS  - 3
SP  - 1-16
EP  - 1-16
PB  - Wiley
SN  - 24754455
KW  - Arabidopsis thaliana
KW  - cell cycle
KW  - cyclin dependent kinase
KW  - cytokinesis
KW  - meiosis
UR  - https://doi.org/10.1002/pld3.477
N2  - Meiosis is a specialized cell division that halves the number of chromosomes in two consecutive rounds of chromosome segregation. In angiosperm plants is meiosis followed by mitotic divisions to form rudimentary haploid gametophytes. In Arabidopsis, termination of meiosis and transition to gametophytic development are governed by TDM1 and SMG7 that mediate inhibition of translation. Mutants deficient in this mechanism do not form tetrads but instead undergo multiple cycles of aberrant nuclear divisions that are likely caused by the failure to downregulate cyclin dependent kinases during meiotic exit. A suppressor screen to identify genes that contribute to meiotic exit uncovered a mutation in cyclin-dependent kinase D;3 (CDKD;3) that alleviates meiotic defects in smg7 deficient plants. The CDKD;3 deficiency prevents aberrant meiotic divisions observed in smg7 mutants or delays their onset after initiation of cytokinesis, which permits formation of functional microspores. Although CDKD;3 acts as an activator of cyclin-dependent kinase A;1 (CDKA;1), the main cyclin dependent kinase that regulates meiosis, cdkd;3 mutation appears to promote meiotic exit independently of CDKA;1. Furthermore, analysis of CDKD;3 interactome revealed enrichment for proteins implicated in cytokinesis, suggesting a more complex function of CDKD;3 in cell cycle regulation.
ER  -

TANASA, Sorin, Neha SHUKLA, Albert CAIRO CALZADA, Sri Ranjani GANJI, Pavlína MIKULKOVÁ, Soňa VALUCHOVÁ, Vivek Kumar RAXWAL, Claudio CAPITAO, Arp SCHNITTGER, Zbyněk ZDRÁHAL a Karel ŘÍHA. A complex role of Arabidopsis CDKD;3 in meiotic progression and cytokinesis. \textit{Plant Direct}. Wiley, 2023, roč.~7, č.~3, s.~1-16. ISSN~2475-4455. Dostupné z: https://dx.doi.org/10.1002/pld3.477.

Podrobný výpis o publikaci