| MRÁZ, Marek, Laura ONDRIŠOVÁ, Václav ŠEDA, Eva HOFERKOVÁ, G. CHIODIN, Kryštof HLAVÁČ, Lenka KOŠŤÁLOVÁ, Gabriela MLADONICKÁ PAVLASOVÁ, Daniel FILIP, Pedro ZENI, Jan OPPELT, Anna PANOVSKÁ, Karla PLEVOVÁ, Šárka POSPÍŠILOVÁ, M. ŠIMKOVIČ, F. VRBACKÝ, Daniel LYSÁK, SM. FERNANDES, A. DAVIDS, A. MAIQUES-DIAZ, S. CHARALAMPOPOULOU, J. MARTIN-SUBERO, J. BROWN, Michael DOUBEK, F. FORCONI a Jiří MAYER. Transcription factor FoxO1 Mediates Adaptive Increase in Akt Activity and Cell Survival During BCR Inhibitor Therapy in CLL. In XX. International Workshop on CLL (iwCLL 2023), Boston, USA. 2023. |
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@proceedings{2356397,
author = {Mráz, Marek and Ondrišová, Laura and Šeda, Václav and Hoferková, Eva and Chiodin, G. and Hlaváč, Kryštof and Košťálová, Lenka and Mladonická Pavlasová, Gabriela and Filip, Daniel and Zeni, Pedro and Oppelt, Jan and Panovská, Anna and Plevová, Karla and Pospíšilová, Šárka and Šimkovič, M. and Vrbacký, F. and Lysák, Daniel and Fernandes, SM. and Davids, A. and MaiquesandDiaz, A. and Charalampopoulou, S. and MartinandSubero, J. and Brown, J. and Doubek, Michael and Forconi, F. and Mayer, Jiří},
booktitle = {XX. International Workshop on CLL (iwCLL 2023), Boston, USA},
keywords = {chronic lymphocytic leukemia; BCR inhibitor therapy; FoxO1},
language = {eng},
title = {Transcription factor FoxO1 Mediates Adaptive Increase in Akt Activity and Cell Survival During BCR Inhibitor Therapy in CLL.},
url = {https://www.vjhemonc.com/video/onkdhuqybo8-transcription-factor-foxo1-mediates-cell-survival-during-bcr-inhibitor-therapy-in-cll/},
year = {2023}
}
TY - CONF
ID - 2356397
AU - Mráz, Marek - Ondrišová, Laura - Šeda, Václav - Hoferková, Eva - Chiodin, G. - Hlaváč, Kryštof - Košťálová, Lenka - Mladonická Pavlasová, Gabriela - Filip, Daniel - Zeni, Pedro - Oppelt, Jan - Panovská, Anna - Plevová, Karla - Pospíšilová, Šárka - Šimkovič, M. - Vrbacký, F. - Lysák, Daniel - Fernandes, SM. - Davids, A. - Maiques-Diaz, A. - Charalampopoulou, S. - Martin-Subero, J. - Brown, J. - Doubek, Michael - Forconi, F. - Mayer, Jiří
PY - 2023
TI - Transcription factor FoxO1 Mediates Adaptive Increase in Akt Activity and Cell Survival During BCR Inhibitor Therapy in CLL.
KW - chronic lymphocytic leukemia
KW - BCR inhibitor therapy
KW - FoxO1
UR - https://www.vjhemonc.com/video/onkdhuqybo8-transcription-factor-foxo1-mediates-cell-survival-during-bcr-inhibitor-therapy-in-cll/
N2 - In this interview, Marek Mráz, PhD, Central European Institute of Technology, Brno, Czech Republic, outlines a study on resistance of chronic lymphocytic leukemia (CLL) to BCR inhibitor therapy through increased activity of the FoxO1-Rictor-pAkt axis. This highlights the potential of FoxO1 as a novel therapeutic target, with testing of a FoxO1 inhibitor in vitro showing its ability to kill CLL cells.This interview was recorded at the biennial International Workshop on Chronic Lymphocytic Leukemia (iwCLL) 2023 meeting, held in Boston, MA.
ER -
MRÁZ, Marek, Laura ONDRIŠOVÁ, Václav ŠEDA, Eva HOFERKOVÁ, G. CHIODIN, Kryštof HLAVÁČ, Lenka KOŠŤÁLOVÁ, Gabriela MLADONICKÁ PAVLASOVÁ, Daniel FILIP, Pedro ZENI, Jan OPPELT, Anna PANOVSKÁ, Karla PLEVOVÁ, Šárka POSPÍŠILOVÁ, M. ŠIMKOVIČ, F. VRBACKÝ, Daniel LYSÁK, SM. FERNANDES, A. DAVIDS, A. MAIQUES-DIAZ, S. CHARALAMPOPOULOU, J. MARTIN-SUBERO, J. BROWN, Michael DOUBEK, F. FORCONI a Jiří MAYER. Transcription factor FoxO1 Mediates Adaptive Increase in Akt Activity and Cell Survival During BCR Inhibitor Therapy in CLL. In \textit{XX. International Workshop on CLL (iwCLL 2023), Boston, USA}. 2023.
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