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@proceedings{2357187,
author = {Škovranová, Gabriela and Molčanová, Lenka and Klančnik, Anja and Jug, Blaž and SmoleandMožina, Sonja and Sychrová, Alice},
booktitle = {PSE Young Scientists’ Meeting 28th – 30th June 2023, Paris, France},
keywords = {antibacterial activity; Paulownia tomentosa; quorum-sensing inhibition; Staphylococcus aureus; wound healing},
language = {eng},
title = {Paulownia tomentosa fruit extracts activity in eradication of Staphylococcus aureus},
year = {2023}
}
TY - CONF
ID - 2357187
AU - Škovranová, Gabriela - Molčanová, Lenka - Klančnik, Anja - Jug, Blaž - Smole-Možina, Sonja - Sychrová, Alice
PY - 2023
TI - Paulownia tomentosa fruit extracts activity in eradication of Staphylococcus aureus
KW - antibacterial activity
KW - Paulownia tomentosa
KW - quorum-sensing inhibition
KW - Staphylococcus aureus
KW - wound healing
N2 - Staphylococcus aureus has a broad virulence capacity and biofilm formation limits the control of wound infections. Paulownia tomentosa Steud. (Paulowniaceae) is a rich source of geranylated phenolics responsible for various bioactivities. Ethanolic extract, chloroform fraction, and three flavonoids showed significant antimicrobial activity. In combination with fusidic acid and mupirocin, synergistic potential was observed. Membrane disruption is partly responsible for the antimicrobial activity of geranylated flavonoids. Selected plant formulations reduced the adhesion of bacteria to the abiotic surface, and also the inhibition of intercellular communication and quorum-sensing was described.
ER -
ŠKOVRANOVÁ, Gabriela, Lenka MOLČANOVÁ, Anja KLANČNIK, Blaž JUG, Sonja SMOLE-MOŽINA a Alice SYCHROVÁ. Paulownia tomentosa fruit extracts activity in eradication of Staphylococcus aureus. In \textit{PSE Young Scientists’ Meeting 28th – 30th June 2023, Paris, France}. 2023.
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