High diversity and sharing of strongylid nematodes in humans
and great apes co-habiting an unprotected area in Cameroon

J 2023

High diversity and sharing of strongylid nematodes in humans and great apes co-habiting an unprotected area in Cameroon

ILÍK, Vladislav, Jakub KREISINGER, David MODRÝ, Erich Marquard SCHWARZ, Nikki TAGG et. al.

Základní údaje

Originální název

High diversity and sharing of strongylid nematodes in humans and great apes co-habiting an unprotected area in Cameroon

Autoři

ILÍK, Vladislav (203 Česká republika, garant, domácí), Jakub KREISINGER, David MODRÝ (203 Česká republika, domácí), Erich Marquard SCHWARZ, Nikki TAGG, Donald MBOHLI, Irene Charmance NKOMBOU, Klara Judita PETRZELKOVA a Barbora PAFCO

Vydání

PLoS neglected tropical diseases, San Francisco, Public Library of Science, 2023, 1935-2735

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30310 Parasitology

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 3.800 v roce 2022

Kód RIV

RIV/00216224:14310/23:00132946

Organizační jednotka

Přírodovědecká fakulta

DOI

http://dx.doi.org/10.1371/journal.pntd.0011499

UT WoS

001093879700002

Klíčová slova anglicky

GASTROINTESTINAL NEMATODES; LOWLAND GORILLAS; RIBOSOMAL DNA; OESOPHAGOSTOMUM; INFECTIONS; SPP.; IDENTIFICATION; TRANSMISSION; BIODIVERSITY; CHIMPANZEES

Štítky

rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 9. 4. 2024 11:30, Mgr. Marie Šípková, DiS.

Anotace

V originále

Rapid increases in human populations and environmental changes of past decades have led to changes in rates of contact and spatial overlap with wildlife. Together with other historical, social and environmental processes, this has significantly contributed to pathogen transmission in both directions, especially between humans and non-human primates, whose close phylogenetic relationship facilitates cross-infections. Using high-throughput amplicon sequencing, we studied strongylid communities in sympatric western lowland gorillas, central chimpanzees and humans co-occurring in an unprotected area in the northern periphery of the Dja Faunal Reserve, Cameroon. At the genus level, we classified 65 strongylid ITS-2 amplicon sequencing variants (ASVs) in humans and great apes. Great apes exhibited higher strongylid diversity than humans. Necator and Oesophagostomum were the most prevalent genera, and we commonly observed mixed infections of more than one strongylid species. Human strongylid communities were dominated by the human hookworm N. americanus, while great apes were mainly infected with N. gorillae, O. stephanostomum and trichostrongylids. We were also able to detect rare strongylid taxa (such as Ancylostoma and Ternidens). We detected eight ASVs shared between humans and great apes (four N. americanus variants, two N. gorillae variants, one O. stephanostomum type I and one Trichostrongylus sp. type II variant). Our results show that knowledge of strongylid communities in primates, including humans, is still limited. Sharing the same habitat, especially outside protected areas (where access to the forest is not restricted), can enable mutual parasite exchange and can even override host phylogeny or conserved patterns. Such studies are critical for assessing the threats posed to all hosts by increasing human-wildlife spatial overlap. In this study, the term "contact" refers to physical contact, while "spatial overlap" refers to environmental contact.

Návaznosti

LM2018132, projekt VaV

Název: Národní centrum lékařské genomiky (Akronym: NCLG)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Národní centrum lékařské genomiky

MUNI/A/1422/2022, interní kód MU

Název: Ekologické faktory a evoluční mechanismy determinující strukturu a funkci biotických společenstev a symbiotických systémů

Investor: Masarykova univerzita, Ekologické faktory a evoluční mechanismy determinující strukturu a funkci biotických společenstev a symbiotických systémů

MUNI/A/1488/2021, interní kód MU

Název: Evoluční a ekologické vztahy a procesy v systémech parazit-hostitel a v biotických systémech vodních organizmů (Akronym: ParaHydro)

Investor: Masarykova univerzita, Evoluční a ekologické vztahy a procesy v systémech parazit-hostitel a v biotických systémech vodních organizmů

90140, velká výzkumná infrastruktura

Název: e-INFRA CZ

90267, velká výzkumná infrastruktura

Název: NCMG III

Citovat

ILÍK, Vladislav, Jakub KREISINGER, David MODRÝ, Erich Marquard SCHWARZ, Nikki TAGG, Donald MBOHLI, Irene Charmance NKOMBOU, Klara Judita PETRZELKOVA a Barbora PAFCO. High diversity and sharing of strongylid nematodes in humans and great apes co-habiting an unprotected area in Cameroon. PLoS neglected tropical diseases. San Francisco: Public Library of Science, 2023, roč. 17, č. 8, s. 1-19. ISSN 1935-2735. Dostupné z: https://dx.doi.org/10.1371/journal.pntd.0011499.

@article{2359537,
   author = {Ilík, Vladislav and Kreisinger, Jakub and Modrý, David and Schwarz, Erich Marquard and Tagg, Nikki and Mbohli, Donald and Nkombou, Irene Charmance and Petrzelkova, Klara Judita and Pafco, Barbora},
   article_location = {San Francisco},
   article_number = {8},
   doi = {http://dx.doi.org/10.1371/journal.pntd.0011499},
   keywords = {GASTROINTESTINAL NEMATODES; LOWLAND GORILLAS; RIBOSOMAL DNA; OESOPHAGOSTOMUM; INFECTIONS; SPP.; IDENTIFICATION; TRANSMISSION; BIODIVERSITY; CHIMPANZEES},
   language = {eng},
   issn = {1935-2735},
   journal = {PLoS neglected tropical diseases},
   title = {High diversity and sharing of strongylid nematodes in humans and great apes co-habiting an unprotected area in Cameroon},
   url = {https://doi.org/10.1371/journal.pntd.0011499},
   volume = {17},
   year = {2023}
}

TY  - JOUR
ID  - 2359537
AU  - Ilík, Vladislav - Kreisinger, Jakub - Modrý, David - Schwarz, Erich Marquard - Tagg, Nikki - Mbohli, Donald - Nkombou, Irene Charmance - Petrzelkova, Klara Judita - Pafco, Barbora
PY  - 2023
TI  - High diversity and sharing of strongylid nematodes in humans and great apes co-habiting an unprotected area in Cameroon
JF  - PLoS neglected tropical diseases
VL  - 17
IS  - 8
SP  - 1-19
EP  - 1-19
PB  - Public Library of Science
SN  - 19352735
KW  - GASTROINTESTINAL NEMATODES
KW  - LOWLAND GORILLAS
KW  - RIBOSOMAL DNA
KW  - OESOPHAGOSTOMUM
KW  - INFECTIONS
KW  - SPP.
KW  - IDENTIFICATION
KW  - TRANSMISSION
KW  - BIODIVERSITY
KW  - CHIMPANZEES
UR  - https://doi.org/10.1371/journal.pntd.0011499
N2  - Rapid increases in human populations and environmental changes of past decades have led to changes in rates of contact and spatial overlap with wildlife. Together with other historical, social and environmental processes, this has significantly contributed to pathogen transmission in both directions, especially between humans and non-human primates, whose close phylogenetic relationship facilitates cross-infections. Using high-throughput amplicon sequencing, we studied strongylid communities in sympatric western lowland gorillas, central chimpanzees and humans co-occurring in an unprotected area in the northern periphery of the Dja Faunal Reserve, Cameroon. At the genus level, we classified 65 strongylid ITS-2 amplicon sequencing variants (ASVs) in humans and great apes. Great apes exhibited higher strongylid diversity than humans. Necator and Oesophagostomum were the most prevalent genera, and we commonly observed mixed infections of more than one strongylid species. Human strongylid communities were dominated by the human hookworm N. americanus, while great apes were mainly infected with N. gorillae, O. stephanostomum and trichostrongylids. We were also able to detect rare strongylid taxa (such as Ancylostoma and Ternidens). We detected eight ASVs shared between humans and great apes (four N. americanus variants, two N. gorillae variants, one O. stephanostomum type I and one Trichostrongylus sp. type II variant). Our results show that knowledge of strongylid communities in primates, including humans, is still limited. Sharing the same habitat, especially outside protected areas (where access to the forest is not restricted), can enable mutual parasite exchange and can even override host phylogeny or conserved patterns. Such studies are critical for assessing the threats posed to all hosts by increasing human-wildlife spatial overlap. In this study, the term "contact" refers to physical contact, while "spatial overlap" refers to environmental contact.
ER  -

ILÍK, Vladislav, Jakub KREISINGER, David MODRÝ, Erich Marquard SCHWARZ, Nikki TAGG, Donald MBOHLI, Irene Charmance NKOMBOU, Klara Judita PETRZELKOVA a Barbora PAFCO. High diversity and sharing of strongylid nematodes in humans and great apes co-habiting an unprotected area in Cameroon. \textit{PLoS neglected tropical diseases}. San Francisco: Public Library of Science, 2023, roč.~17, č.~8, s.~1-19. ISSN~1935-2735. Dostupné z: https://dx.doi.org/10.1371/journal.pntd.0011499.

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