NIKOLI, Marek, Vojtech VIKTORIN, Peter ZACH, Filip TYLS, Daniela DUDYSOVA, Karolina JANKU, Jana KOPIVOVA, Martin KUCHAR, Martin BRUNOVSKY, Jiri HORACEK a Tomas PALENICEK. Psilocybin intoxication did not affect daytime or sleep-related declarative memory consolidation in a small sample exploratory analysis. European Neuropsychopharmacology. Amsterdam (The Netherlands): Elsevier, 2023, roč. 74, na, s. 78-88. ISSN 0924-977X. Dostupné z: https://dx.doi.org/10.1016/j.euroneuro.2023.04.019.
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Základní údaje
Originální název Psilocybin intoxication did not affect daytime or sleep-related declarative memory consolidation in a small sample exploratory analysis
Autoři NIKOLI, Marek, Vojtech VIKTORIN, Peter ZACH, Filip TYLS, Daniela DUDYSOVA, Karolina JANKU, Jana KOPIVOVA, Martin KUCHAR, Martin BRUNOVSKY, Jiri HORACEK a Tomas PALENICEK.
Vydání European Neuropsychopharmacology, Amsterdam (The Netherlands), Elsevier, 2023, 0924-977X.
Další údaje
Originální jazyk angličtina
Typ výsledku Článek v odborném periodiku
Obor 30230 Other clinical medicine subjects
Stát vydavatele Nizozemské království
Utajení není předmětem státního či obchodního tajemství
WWW URL
Impakt faktor Impact factor: 5.600 v roce 2022
Kód RIV RIV/00216224:90249/23:00132960
Organizační jednotka CZECRIN IV
Doi http://dx.doi.org/10.1016/j.euroneuro.2023.04.019
UT WoS 001034059600001
Klíčová slova česky Psilocybin; Psychedelics; Healthy volunteers; Memory consolidation; Cognition
Klíčová slova anglicky Psilocybin; Psychedelics; Healthy volunteers; Memory consolidation; Cognition
Štítky Excelence Science, neMU, NÚDZ, RIV, user, článek v časopise
Příznaky Mezinárodní význam, Recenzováno
Změnil Změnil: Mgr. Michal Petr, učo 65024. Změněno: 12. 4. 2024 12:57.
Anotace
Psilocybin is investigated as a fast-acting antidepressant used in conjunction with psychother-apy. Intact cognitive functions, including memory, are one of the basic conditions of effective psychedelic-assisted therapy. While cognitive and memory processing is attenuated on various domains during psilocybin intoxication, the effect of psilocybin on the consolidation of memo-ries learned outside of acute intoxication is not known. Thus the main aim of the current study was to test the effects of psilocybin on (A) memory consolidation of previously learned material just after the psilocybin session and (B) on overnight memory consolidation the night just after the psilocybin session. 20 healthy volunteers (10 M/10F) were enrolled in a placebo-controlled, double-blind, cross-over design. Effects on declarative memory consolidation in condition (A) The Groton Maze Learning Task and Rey Auditory Verbal Learning Test were used, and for (B) the Pair Associative Learning Test was used. We did not find psilocybin to improve memory consoli-dation. At the same time, we did not find psilocybin to negatively affect memory consolidation in any of the tests used. This evidence adds to the safety profile for the use of psilocybin.& COPY; 2023 Elsevier B.V. and ECNP. All rights reserved.
Návaznosti
90249, velká výzkumná infrastrukturaNázev: CZECRIN IV
VytisknoutZobrazeno: 12. 5. 2024 14:01