| JHENG, Pei-Ru, Chia-Che CHIANG, Jiunn-Horng KANG, Yu-Jui FAN, Kevin C. -W. WU, Yan-Ting CHEN, Jia-Wei LIANG, Nima BOLOUKI, Jyh-Wei LEE, Jang-Hsing HSIEH a Er-Yuan CHUANG. Cold atmospheric plasma-enabled platelet vesicle incorporated iron oxide nano-propellers for thrombolysis. Materials Today Bio. Elsevier, 2023, roč. 23, December, s. 1-14. ISSN 2590-0064. Dostupné z: https://dx.doi.org/10.1016/j.mtbio.2023.100876. |
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@article{2361677,
author = {Jheng, PeiandRu and Chiang, ChiaandChe and Kang, JiunnandHorng and Fan, YuandJui and Wu, Kevin C. andW. and Chen, YanandTing and Liang, JiaandWei and Bolouki, Nima and Lee, JyhandWei and Hsieh, JangandHsing and Chuang, ErandYuan},
article_number = {December},
doi = {http://dx.doi.org/10.1016/j.mtbio.2023.100876},
keywords = {Cold atmospheric plasma; Iron oxide; Platelet vesicle; Phototherapy; Magnetotherapy; Thrombolysis},
language = {eng},
issn = {2590-0064},
journal = {Materials Today Bio},
title = {Cold atmospheric plasma-enabled platelet vesicle incorporated iron oxide nano-propellers for thrombolysis},
url = {https://doi.org/10.1016/j.mtbio.2023.100876},
volume = {23},
year = {2023}
}
TY - JOUR
ID - 2361677
AU - Jheng, Pei-Ru - Chiang, Chia-Che - Kang, Jiunn-Horng - Fan, Yu-Jui - Wu, Kevin C. -W. - Chen, Yan-Ting - Liang, Jia-Wei - Bolouki, Nima - Lee, Jyh-Wei - Hsieh, Jang-Hsing - Chuang, Er-Yuan
PY - 2023
TI - Cold atmospheric plasma-enabled platelet vesicle incorporated iron oxide nano-propellers for thrombolysis
JF - Materials Today Bio
VL - 23
IS - December
SP - 1-14
EP - 1-14
PB - Elsevier
SN - 25900064
KW - Cold atmospheric plasma
KW - Iron oxide
KW - Platelet vesicle
KW - Phototherapy
KW - Magnetotherapy
KW - Thrombolysis
UR - https://doi.org/10.1016/j.mtbio.2023.100876
N2 - A new approach to treating vascular blockages has been developed to overcome the limitations of current thrombolytic therapies. This approach involves biosafety and multimodal plasma-derived theranostic platelet vesicle incorporating iron oxide constructed nano-propellers platformed technology that possesses fluorescent and magnetic features and manifold thrombus targeting modes. The platform is capable of being guided and visualized remotely to specifically target thrombi, and it can be activated using near-infrared phototherapy along with an actuated magnet for magnetotherapy. In a murine model of thrombus lesion, this proposed multimodal approach showed an approximately 80% reduction in thrombus residues. Moreover, the new strategy not only improves thrombolysis but also boosts the rate of lysis, making it a promising candidate for time-sensitive thrombolytic therapy.
ER -
JHENG, Pei-Ru, Chia-Che CHIANG, Jiunn-Horng KANG, Yu-Jui FAN, Kevin C. -W. WU, Yan-Ting CHEN, Jia-Wei LIANG, Nima BOLOUKI, Jyh-Wei LEE, Jang-Hsing HSIEH a Er-Yuan CHUANG. Cold atmospheric plasma-enabled platelet vesicle incorporated iron oxide nano-propellers for thrombolysis. \textit{Materials Today Bio}. Elsevier, 2023, roč.~23, December, s.~1-14. ISSN~2590-0064. Dostupné z: https://dx.doi.org/10.1016/j.mtbio.2023.100876.
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