The effect of space travel on human reproductive health: a
systematic review

J 2024

The effect of space travel on human reproductive health: a systematic review

GIMUNOVÁ, Marta, Ana Carolina PALUDO, Martina BERNACIKOVÁ a Julie DOBROVOLNÁ

Základní údaje

Originální název

The effect of space travel on human reproductive health: a systematic review

Autoři

GIMUNOVÁ, Marta (203 Česká republika, garant, domácí), Ana Carolina PALUDO (76 Brazílie, domácí), Martina BERNACIKOVÁ (203 Česká republika, domácí) a Julie DOBROVOLNÁ (203 Česká republika, domácí)

Vydání

NPJ MICROGRAVITY, UNITED STATES, NATURE PORTFOLIO, 2024, 2373-8065

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30300 3.3 Health sciences

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

odkaz na full text

Impakt faktor

Impact factor: 5.100 v roce 2022

Organizační jednotka

Fakulta sportovních studií

DOI

http://dx.doi.org/10.1038/s41526-024-00351-1

UT WoS

001144704200001

Klíčová slova anglicky

space travel; reproductive health; astronauts

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 5. 2. 2024 15:57, Mgr. Marta Gimunová, Ph.D.

Anotace

V originále

With increasing possibilities of multi-year missions in deep space, colonizing other planets, and space tourism, it is important to investigate the effects of space travel on human reproduction. This study aimed to systematically review and summarize the results of available literature on space travel, microgravity, and space radiation, or Earth-based spaceflight analogues impact on female and male reproductive functions in humans. This systematic review was performed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines and Space Biomedicine Systematic Review methods. The search was performed using three databases: PubMed, Web of Science, and Medline Complete. During the database search, 364 studies were identified. After the study selection process, 16 studies were included in the review. Five studies included female participants, and the findings show an increased risk of thromboembolism in combined oral contraceptive users, decreased decidualization, functional insufficiency of corpus luteum, and decreased progesterone and LH levels related to space travel or its simulation. Male participants were included in 13 studies. In males, reproductive health considerations focused on the decrease in testosterone and sex hormone-binding globulin levels, the ratio of male offspring, sperm motility, sperm vitality, and the increase in sperm DNA fragmentation related to space travel or its simulation. Results of this systematic review highlight the need to focus more on the astronaut’s reproductive health in future research, as only 16 studies were found during the literature search, and many more research questions related to reproductive health in astronauts still need to be answered.

Citovat

GIMUNOVÁ, Marta, Ana Carolina PALUDO, Martina BERNACIKOVÁ a Julie DOBROVOLNÁ. The effect of space travel on human reproductive health: a systematic review. NPJ MICROGRAVITY. UNITED STATES: NATURE PORTFOLIO, 2024, roč. 10, č. 10, s. 1-9. ISSN 2373-8065. Dostupné z: https://dx.doi.org/10.1038/s41526-024-00351-1.

@article{2364448,
   author = {Gimunová, Marta and Paludo, Ana Carolina and Bernaciková, Martina and Dobrovolná, Julie},
   article_location = {UNITED STATES},
   article_number = {10},
   doi = {http://dx.doi.org/10.1038/s41526-024-00351-1},
   keywords = {space travel; reproductive health; astronauts},
   language = {eng},
   issn = {2373-8065},
   journal = {NPJ MICROGRAVITY},
   title = {The effect of space travel on human reproductive health: a systematic review},
   url = {http://www.nature.com/articles/s41526-024-00351-1},
   volume = {10},
   year = {2024}
}

TY  - JOUR
ID  - 2364448
AU  - Gimunová, Marta - Paludo, Ana Carolina - Bernaciková, Martina - Dobrovolná, Julie
PY  - 2024
TI  - The effect of space travel on human reproductive health: a systematic review
JF  - NPJ MICROGRAVITY
VL  - 10
IS  - 10
SP  - 1-9
EP  - 1-9
PB  - NATURE PORTFOLIO
SN  - 23738065
KW  - space travel
KW  - reproductive health
KW  - astronauts
UR  - http://www.nature.com/articles/s41526-024-00351-1
N2  - With increasing possibilities of multi-year missions in deep space, colonizing other planets, and space tourism, it is important to investigate the effects of space travel on human reproduction. This study aimed to systematically review and summarize the results of available literature on space travel, microgravity, and space radiation, or Earth-based spaceflight analogues impact on female and male reproductive functions in humans. This systematic review was performed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines and Space Biomedicine Systematic Review methods. The search was performed using three databases: PubMed, Web of Science, and Medline Complete. During the database search, 364 studies were identified. After the study selection process, 16 studies were included in the review. Five studies included female participants, and the findings show an increased risk of thromboembolism in combined oral contraceptive users, decreased decidualization, functional insufficiency of corpus luteum, and decreased progesterone and LH levels related to space travel or its simulation. Male participants were included in 13 studies. In males, reproductive health considerations focused on the decrease in testosterone and sex hormone-binding globulin levels, the ratio of male offspring, sperm motility, sperm vitality, and the increase in sperm DNA fragmentation related to space travel or its simulation. Results of this systematic review highlight the need to focus more on the astronaut’s reproductive health in future research, as only 16 studies were found during the literature search, and many more research questions related to reproductive health in astronauts still need to be answered.
ER  -

GIMUNOVÁ, Marta, Ana Carolina PALUDO, Martina BERNACIKOVÁ a Julie DOBROVOLNÁ. The effect of space travel on human reproductive health: a systematic review. \textit{NPJ MICROGRAVITY}. UNITED STATES: NATURE PORTFOLIO, 2024, roč.~10, č.~10, s.~1-9. ISSN~2373-8065. Dostupné z: https://dx.doi.org/10.1038/s41526-024-00351-1.

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